Protein Alignment Wee1 and wee-1.3

DIOPT Version :10

• Sequence 1: NP_477035.1
• Gene: Wee1 / 33965
• FlyBaseID: FBgn0011737
• Length: 609
• Species: Drosophila melanogaster
• Sequence 2: NP_496095.1
• Gene: wee-1.3 / 174531
• WormBaseID: WBGene00006940
• Length: 677
• Species: Caenorhabditis elegans
• Alignment Length: 317
• Identity: 106/317 - (33%)
• Similarity: 155/317 - (48%)
• Gaps: 52/317 - (16%)

  Fly   220 QAPKRL---ALHDTNISRFKREFMQVN-VIGVGEFGVVFQCVNRLDGCIYAIKKSKKPVAGSSFE 280
            |.||.|   ....||...|..:..|:: :||.|.||.||....|.|..:||:|.|..|:...|..
 Worm    85 QGPKPLESPKYDHTNAQSFFEQVFQIDEIIGRGSFGEVFAARCREDSQLYAVKVSLAPIRQHSIS 149

  Fly   281 KRALNEVWAHAVLGKHDNVVRYYSAWAEDDHMLIQNEFCDGGSLHARIQDHCLGEAELKIVLMHV 345
            |  ..|..:|.::..|.|:|::|.||.|...:.||.|.||...|....:.|.|.|.|:..:.:.:
 Worm   150 K--YREAESHMIIPPHKNLVKFYRAWEETGRLYIQTELCDQSLLKYCTEKHALPEDEIWNIFVDL 212

  Fly   346 IEGLRYIHSNDLVHMDLKPENIFSTMNPNAHKLVEVQPQQTKDDDGMDSVYEELRHSENLVTYKI 410
            ::.:.::||||::|.|:||||||                .|||                 :..|:
 Worm   213 LQAVHHLHSNDMIHDDIKPENIF----------------LTKD-----------------MICKL 244

  Fly   411 GDLGHVTSVKEP----YVEEGDCRYLPKEILHEDYSNLFKADIFSLGITLFEAAGGGPLPKNGPE 471
            ||.|.|.::|.|    ..||||.:||..|:|:...:.  .:||||||:|:.||.....:|.||..
 Worm   245 GDFGLVINLKNPNDVKSAEEGDSKYLAPEVLNGRPTK--SSDIFSLGMTILEATTDLDVPSNGDS 307

  Fly   472 WHNLRDGKVP--ILPSLSRDFNELIAQMMHPYPDKRPTSQSIFSHPILSAVDSKSKL 526
            ||.:|:|::|  ....:|.|...|||.|:...|..||||:.:..||::     |.||
 Worm   308 WHQIRNGQIPDRFFAGISTDLRSLIALMLDSDPRIRPTSRDLLDHPVI-----KKKL 359

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wee1	NP_477035.1	PTKc_Wee1	238..516	CDD:270953	95/284 (33%)
wee-1.3	NP_496095.1	PKc_Myt1	106..353	CDD:270952	94/283 (33%)