Protein Alignment Wee1 and PDIK1L

DIOPT Version :10

• Sequence 1: NP_477035.1
• Gene: Wee1 / 33965
• FlyBaseID: FBgn0011737
• Length: 609
• Species: Drosophila melanogaster
• Sequence 2: NP_690048.1
• Gene: PDIK1L / 149420
• HGNCID: 18981
• Length: 341
• Species: Homo sapiens
• Alignment Length: 339
• Identity: 76/339 - (22%)
• Similarity: 121/339 - (35%)
• Gaps: 103/339 - (30%)

  Fly   242 VNVIGVGEFGVVFQCVNRLDGCIYAIKKSKKPVAGSSFEKRALNEVWA-HAVLGKHDNVVRYYSA 305
            :..:|.|.:|||::.|.|......|:||.:.. |..:.| .||.|.|| .::..:|.||:.....
Human    11 IREVGRGSYGVVYEAVIRKTSARVAVKKIRCH-APENVE-LALREFWALSSIKSQHPNVIHLEEC 73

  Fly   306 WAEDDHM---------------LIQN--------------------EFCDGGSLHARIQDHCLGE 335
            ..:.|.|               |::.                    :|||||.::..:.......
Human    74 ILQKDGMVQKMSHGSNSSLYLQLVETSLKGEIAFDPRSAYYLWFVMDFCDGGDMNEYLLSRKPNR 138

  Fly   336 AELKIVLMHVIEGLRYIHSNDLVHMDLKPENIFSTMNPNAHKLVEVQPQQTKDDDGMDSVYEELR 400
            ......::.:...|.::|.|.::|.||||:||..:              ||:.|.
Human   139 KTNTSFMLQLSSALAFLHKNQIIHRDLKPDNILIS--------------QTRLDT---------- 179

  Fly   401 HSENLVTYKIGDLG--HVTSVKEPYVEE-------------GDCRYLPKEILHEDYSNLFKADIF 450
             |:...|.|:.|.|  .|.|......||             |...|:..|:....|:  .|||||
Human   180 -SDLEPTLKVADFGLSKVCSASGQNPEEPVSVNKCFLSTACGTDFYMAPEVWEGHYT--AKADIF 241

  Fly   451 SLGITLFEAAGG-------------GPLPKNGPE-----WHNLRDGKVPIL-----PSLSRDFNE 492
            :|||.::.....             |...|.|.|     ...|.:.|:.:|     .|::....:
Human   242 ALGIIIWAMLERITFIDTETKKELLGSYVKQGTEIVPVGEALLENPKMELLIPVKKKSMNGRMKQ 306

  Fly   493 LIAQMMHPYPDKRP 506
            ||.:|:...|..||
Human   307 LIKEMLAANPQDRP 320

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wee1	NP_477035.1	PTKc_Wee1	238..516	CDD:270953	76/339 (22%)
PDIK1L	NP_690048.1	STKc_PDIK1L	7..331	CDD:270879	76/339 (22%)