Protein Alignment Wee1 and PDIK1L

DIOPT Version :9

• Sequence 1: NP_001260167.1
• Gene: Wee1 / 33965
• FlyBaseID: FBgn0011737
• Length: 609
• Species: Drosophila melanogaster
• Sequence 2: NP_001230461.1
• Gene: PDIK1L / 149420
• HGNCID: 18981
• Length: 341
• Species: Homo sapiens
• Alignment Length: 339
• Identity: 76/339 - (22%)
• Similarity: 121/339 - (35%)
• Gaps: 103/339 - (30%)

  Fly   242 VNVIGVGEFGVVFQCVNRLDGCIYAIKKSKKPVAGSSFEKRALNEVWA-HAVLGKHDNVVRYYSA 305
            :..:|.|.:|||::.|.|......|:||.:.. |..:.| .||.|.|| .::..:|.||:.....
Human    11 IREVGRGSYGVVYEAVIRKTSARVAVKKIRCH-APENVE-LALREFWALSSIKSQHPNVIHLEEC 73

  Fly   306 WAEDDHM---------------LIQN--------------------EFCDGGSLHARIQDHCLGE 335
            ..:.|.|               |::.                    :|||||.::..:.......
Human    74 ILQKDGMVQKMSHGSNSSLYLQLVETSLKGEIAFDPRSAYYLWFVMDFCDGGDMNEYLLSRKPNR 138

  Fly   336 AELKIVLMHVIEGLRYIHSNDLVHMDLKPENIFSTMNPNAHKLVEVQPQQTKDDDGMDSVYEELR 400
            ......::.:...|.::|.|.::|.||||:||..:              ||:.|.
Human   139 KTNTSFMLQLSSALAFLHKNQIIHRDLKPDNILIS--------------QTRLDT---------- 179

  Fly   401 HSENLVTYKIGDLG--HVTSVKEPYVEE-------------GDCRYLPKEILHEDYSNLFKADIF 450
             |:...|.|:.|.|  .|.|......||             |...|:..|:....|:  .|||||
Human   180 -SDLEPTLKVADFGLSKVCSASGQNPEEPVSVNKCFLSTACGTDFYMAPEVWEGHYT--AKADIF 241

  Fly   451 SLGITLFEAAGG-------------GPLPKNGPE-----WHNLRDGKVPIL-----PSLSRDFNE 492
            :|||.::.....             |...|.|.|     ...|.:.|:.:|     .|::....:
Human   242 ALGIIIWAMLERITFIDTETKKELLGSYVKQGTEIVPVGEALLENPKMELLIPVKKKSMNGRMKQ 306

  Fly   493 LIAQMMHPYPDKRP 506
            ||.:|:...|..||
Human   307 LIKEMLAANPQDRP 320

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wee1	NP_001260167.1	PTKc_Wee1	238..516	CDD:270953	76/339 (22%)
		Pkinase	239..515	CDD:278497	76/339 (22%)
PDIK1L	NP_001230461.1	STKc_PDIK1L	7..331	CDD:270879	76/339 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165158336
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930