Protein Alignment Wee1 and wee1

DIOPT Version :10

• Sequence 1: NP_477035.1
• Gene: Wee1 / 33965
• FlyBaseID: FBgn0011737
• Length: 609
• Species: Drosophila melanogaster
• Sequence 2: NP_001120437.1
• Gene: wee1 / 100145524
• XenbaseID: XB-GENE-6455482
• Length: 601
• Species: Xenopus tropicalis
• Alignment Length: 637
• Identity: 250/637 - (39%)
• Similarity: 332/637 - (52%)
• Gaps: 128/637 - (20%)

  Fly    23 SRSPSPQVFNP--RKLRFADDDFDKD---------TPEGASPQHPL--------QQRPKLSSGEE 68
            |:.|......|  .||.|:|.:.::|         ..|..||...|        :.||...|.||
 Frog     8 SQPPRTMSLQPVRHKLFFSDTEEEEDGHSTGEDSAFQESDSPVSGLRGGPTAKPEGRPPGGSWEE 72

  Fly    69 QQLDSKIG----KEGGDGDVSMS--------------------------------PPCQKVRALR 97
            ::.:..||    |..||..:|.|                                ||.:..|.||
 Frog    73 EEEEEGIGSSPIKSPGDYFMSGSPTYRELAPESPAGYGSRSPQGPGSPIPECPGTPPHKTFRKLR 137

  Fly    98 LFSTPATPKTILQKSTTQCSNHLSAAAAAVNASR-RSDDLFRLSERPRSLPLHNRKLPTQD---- 157
            ||.||.|||::|.|          |.....:|.| |...|||.:|          |:|..:
 Frog   138 LFDTPHTPKSLLSK----------ARGIGSSALRFRGGSLFREAE----------KVPKPEFVYS 182

  Fly   158 --TANVNPFTPDSL-MAHNKKRCRTQFGRENLNLNVNAMQKYLLSDACDDDVTEEAGDSMREIHQ 219
              ..|:|||||||| :..:...||.:             ::.||:|:|.:|:  |..|...|...
 Frog   183 TPQVNINPFTPDSLEIQSSTGLCRRR-------------KRALLNDSCGEDM--EGSDCELEDDD 232

  Fly   220 QAP-KRLALHDTNI-SRFKREFMQVNVIGVGEFGVVFQCVNRLDGCIYAIKKSKKPVAGSSFEKR 282
            ..| ||:.:.::|: ||:..||.::..||.||||.||:||.||||||||||:||||:|||..|:.
 Frog   233 IRPAKRIPITESNMKSRYATEFHELEKIGSGEFGSVFKCVKRLDGCIYAIKRSKKPLAGSVDEQN 297

  Fly   283 ALNEVWAHAVLGKHDNVVRYYSAWAEDDHMLIQNEFCDGGSLHARIQDH-----CLGEAELKIVL 342
            ||.||:||||||:|.:|||||||||||||||||||.|:||||...|.::     ...|.|||.:|
 Frog   298 ALREVYAHAVLGQHPHVVRYYSAWAEDDHMLIQNEHCNGGSLADAISENYRTMQFFSEPELKDLL 362

  Fly   343 MHVIEGLRYIHSNDLVHMDLKPENIFSTMNPNAHKLVEVQPQQTKDDDGMDSVYEELRHSENLVT 407
            :.|..||:||||..|||||:||.|||.:.....:..||     ..||:...|         ..|.
 Frog   363 LQVARGLKYIHSMSLVHMDIKPSNIFISRTTVPNTAVE-----EGDDEDCGS---------RKVI 413

  Fly   408 YKIGDLGHVTSVKEPYVEEGDCRYLPKEILHEDYSNLFKADIFSLGITLFEAAGGGPLPKNGPEW 472
            ||||||||||.|..|.|||||.|:|..|:|.|||::|.|||||:|.:|::.|||..|||.||.:|
 Frog   414 YKIGDLGHVTRVSSPQVEEGDSRFLANEVLQEDYTHLPKADIFALALTVWCAAGAEPLPTNGEQW 478

  Fly   473 HNLRDGKVPILP-SLSRDFNELIAQMMHPYPDKRPTSQSIFSHPILSAVDSKSKLQLGLELTVEK 536
            |.:|.||:|.:| |||.:|.:||..|:.|.|:|||:|.::..|.:|.:...||..||.:||..||
 Frog   479 HEIRQGKLPRVPQSLSLEFMDLIKLMISPDPEKRPSSVALVKHSVLLSASRKSAEQLRIELNAEK 543

  Fly   537 RKNEILMNKLREAKKQIKLLEQR--------VNLLAVTNNPDSLDGQRCLRS 580
            .||.:|..:|::|:......|:|        ....|..|....|.|::..||
 Frog   544 FKNALLQKELKKAQIAKAAAEERALFPDRVVTRSTAQNNRTTRLIGKKMNRS 595

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wee1	NP_477035.1	PTKc_Wee1	238..516	CDD:270953	155/283 (55%)
wee1	NP_001120437.1	PTKc_Wee1a	248..523	CDD:271040	157/288 (55%)