Protein Alignment Polr1F and POLR1F

DIOPT Version :10

• Sequence 1: NP_609081.1
• Gene: Polr1F / 33963
• FlyBaseID: FBgn0042092
• Length: 253
• Species: Drosophila melanogaster
• Sequence 2: NP_001002926.1
• Gene: POLR1F / 221830
• HGNCID: 18027
• Length: 338
• Species: Homo sapiens
• Alignment Length: 269
• Identity: 72/269 - (26%)
• Similarity: 121/269 - (44%)
• Gaps: 51/269 - (18%)

  Fly    15 ELENYA------SSPESCVRCITTDMHLAMGPYGM----ANFKHALHELLIRTKVGFYDSGLDGI 69
            ||..||      :|..||:.......|:|:.|..:    ...:..|...|:|     |...|.|:
Human    30 ELPTYAAACALVNSRYSCLVAGPHQRHIALSPRYLNRKRTGIREQLDAELLR-----YSESLLGV 89

  Fly    70 VLGIKNIKVLGQTAGLRADDPTMHLVINADFYVFRPKAGAILSGVVRHISRHHVSAVIYRVFNTS 134
            .:...||||:|:...:..|...:||.|.|||.:|.|:.|..|.|:|..:|..|:..:::..||.|
Human    90 PIAYDNIKVVGELGDIYDDQGHIHLNIEADFVIFCPEPGQKLMGIVNKVSSSHIGCLVHGCFNAS 154

  Fly   135 IRFTNQSASRE----DIAMDQEIKIRIKNFDISNLMPY-IEGEL---------------LLENG- 178
            |....|.::.:    :|.|..|::..:...|......: |.|:|               :.|||
Human   155 IPKPEQLSAEQWQTMEINMGDELEFEVFRLDSDAAGVFCIRGKLNITSLQFKRSEVSEEVTENGT 219

  Fly   179 -EAPKNKSIKFGSPPPEEKEVKKEDPDEM-LDALITEIKKEPEFTPRKKTSTKRKNGENG---DT 238
             ||.|.         |::|: ||:||:.. :|:..|::..:.:.||.::::.:..|..||   :.
Human   220 EEAAKK---------PKKKK-KKKDPETYEVDSGTTKLADDADDTPMEESALQNTNNANGIWEEE 274

  Fly   239 TKTKKVKKE 247
            .|.||.||:
Human   275 PKKKKKKKK 283

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Polr1F	NP_609081.1	RNAP_I_Rpa43_N	19..107	CDD:239820	28/97 (29%)
		RPA43_OB	105..>135	CDD:465545	9/29 (31%)
POLR1F	NP_001002926.1	RNAP_I_Rpa43_N	40..126	CDD:239820	25/90 (28%)
		RPA43_OB	125..>157	CDD:465545	11/31 (35%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	209..338		24/85 (28%)