Protein Alignment Nlg2 and Ache

DIOPT Version :9

• Sequence 1: NP_001245916.1
• Gene: Nlg2 / 33962
• FlyBaseID: FBgn0031866
• Length: 1248
• Species: Drosophila melanogaster
• Sequence 2: XP_038945765.1
• Gene: Ache / 83817
• RGDID: 69313
• Length: 616
• Species: Rattus norvegicus
• Alignment Length: 652
• Identity: 192/652 - (29%)
• Similarity: 280/652 - (42%)
• Gaps: 135/652 - (20%)

  Fly   153 PGHPEACALLVLLLLTSLWPDCCECLHGGSNT---------VKTKYGLLRGIVVRS--SPLVEAF 206
            |.|..:.|..:|.||.||       |.||:..         |:.:.|.||||.:::  .| |.||
  Rat     7 PLHTPSLASPLLFLLLSL-------LGGGARAEGREDPQLLVRVRGGQLRGIRLKAPGGP-VSAF 63

  Fly   207 LGIPYASPPVGSLRFMPPITPSTWKTVRSADRFSPVCPQNI-PIPPNGPEALLEVPRARLAQLRR 270
            ||||:|.|||||.|||||.....|..:..|..|..||.|.: .:.|......:..|...|
  Rat    64 LGIPFAEPPVGSRRFMPPEPKRPWSGILDATTFQNVCYQYVDTLYPGFEGTEMWNPNREL----- 123

  Fly   271 LLPLLKNQSEDCLYLNIYVPYETRRQRRNTDDTTGEPKTKLSTVVFIHGESY--DWNSGNPYDGS 333
                    ||||||||::.||.             .|.:....:::|:|..:  ..:|.:.|||.
  Rat   124 --------SEDCLYLNVWTPYP-------------RPTSPTPVLIWIYGGGFYSGASSLDVYDGR 167

  Fly   334 ELAAHGNVIVVTINFRLGIFGFLKTGGKESAQGNFGLMDLVAGLHWLKENLPAFGGDPQSITLLG 398
            .||.....::|::|:|:|.||||...|...|.||.||:|....|.|::||:.||||||.|:||.|
  Rat   168 FLAQVEGTVLVSMNYRVGTFGFLALPGSRDAPGNVGLLDQRLALQWVQENIAAFGGDPMSVTLFG 232

  Fly   399 YGTGAVLANILVVSPVASDLIQRTVLVSGSALSPWA-IQKNPLFVKRR---VAEQTGC------H 453
            ...||....:.::|..:..|..|.||.||:...||| :....  .:||   :|...||      .
  Rat   233 ESAGAASVGMHILSLPSRSLFHRAVLQSGTPNGPWATVSAGE--ARRRATLLARLVGCPPGGAGG 295

  Fly   454 GDMLYDDLAPCLRTKSVAELLAVKVDH-----PR---FLVGFAPFVDGTVISPGANPLGSTTLPL 510
            .|   .:|..||||:...:|    |||     |:   |...|.|.|||..:|.  .|
  Rat   296 ND---TELISCLRTRPAQDL----VDHEWHVLPQESIFRFSFVPVVDGDFLSD--TP-------- 343

  Fly   511 GSAIVSTSGIEYANFPKRDLIFCLTSVESYLDLSAQDLEF---GFNETRRDRILR----TFVRNN 568
             .|:::|...:       ||...:..|:   |..:..|.:   ||::.....|.|    ..||..
  Rat   344 -EALINTGDFQ-------DLQVLVGVVK---DEGSYFLVYGVPGFSKDNESLISRAQFLAGVRIG 397

  Fly   569 FHYHLNEIFAVLKNEYTDWEKAIRNPLSSRDATLQFLSDGHTASPLIKLGYMHSLRGGRAYFLHF 633
            .....:.....:...||||... .:|...|||....:.|.:...|:.:|....:.:|.|.|...|
  Rat   398 VPQASDLAAEAVVLHYTDWLHP-EDPAHLRDAMSAVVGDHNVVCPVAQLAGRLAAQGARVYAYIF 461

  Fly   634 KHKTIEEEYPQRSGSVRGEDVPFWLGLPMSPLFPHNYTTQERQIGRLMLRYLSNFAKTGNPNQST 698
            :|:.....:|...|...|.::.|..|||:.|..  |||.:||...:.:::|.:|||:||:||
  Rat   462 EHRASTLTWPLWMGVPHGYEIEFIFGLPLDPSL--NYTVEERIFAQRLMKYWTNFARTGDPN--- 521

  Fly   699 AKSVLPNPNEVLETALHQQKKRSTSLTHPNLSEALNLAVLYNQRRSNAMHEKRSYIRRRLRSNDA 763
                  :|.:            |.|...|..:.|....|        :::.|...:||.||:...
  Rat   522 ------DPRD------------SKSPRWPPYTTAAQQYV--------SLNLKPLEVRRGLRAQTC 560

  Fly   764 AF 765
            ||
  Rat   561 AF 562

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg2	NP_001245916.1	COesterase	182..712	CDD:278561	169/568 (30%)
Ache	XP_038945765.1	COesterase	37..563	CDD:395084	181/615 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910