Protein Alignment Nlg2 and Ces1h

DIOPT Version :10

• Sequence 1: NP_523496.1
• Gene: Nlg2 / 33962
• FlyBaseID: FBgn0031866
• Length: 1248
• Species: Drosophila melanogaster
• Sequence 2: NP_001357759.1
• Gene: Ces1h / 75704
• MGIID: 1922954
• Length: 562
• Species: Mus musculus
• Alignment Length: 684
• Identity: 183/684 - (26%)
• Similarity: 283/684 - (41%)
• Gaps: 198/684 - (28%)

  Fly   160 ALLVLLLLTSLW------PDCCECLHGGSNTVKTKYGLLRGIVVRSSPLVEAFLGIPYASPPVGS 218
            ||::|.|....|      |......||   .|..||..|.|.   :.| |..|||:|:|.||:||
Mouse     5 ALILLSLSAMAWGGYPSSPPVVNTTHG---KVLGKYISLEGF---TQP-VAVFLGVPFAKPPLGS 62

  Fly   219 LRFMPPITPSTWKTVRSADRFSPVCPQNIPIPPNGPEALLEVPRARLAQLRRLLPLLKNQ----- 278
            |||.||..|..|..|::|..:.|:|.|:                |.|.|:...| ::.|:
Mouse    63 LRFAPPQPPEPWSFVKNATSYPPMCSQD----------------AVLGQMVNDL-IINNKEKIRL 110

  Fly   279 --SEDCLYLNIYVPYETRRQRRNTDDTTGEPKTKLSTVVFIHGESYDWNSGNPYDGSELAAHGNV 341
              ||||||||:|.|.:.   .:||:        :|..:|:|||........:.|||..|:||.||
Mouse   111 RFSEDCLYLNVYTPVDL---MKNTN--------RLPVMVWIHGGGLVVGGASAYDGRTLSAHENV 164

  Fly   342 IVVTINFRLGIFGFLKTGGKESAQGNFGLMDLVAGLHWLKENLPAFGGDPQSITLLGYGTGAVLA 406
            :||||.:||.|:||..| |.|.::||:|.:|.:|.|||:::|:..|||||.|:|:.|...|....
Mouse   165 VVVTIQYRLAIWGFFST-GDEHSRGNWGHLDQLAALHWIQDNIANFGGDPGSVTIFGQSAGGESV 228

  Fly   407 NILVVSPVASDLIQRTVLVSGSALSPWAIQKNPLFVKRRVAEQTGC---------HGDMLYDDLA 462
            ::||:||:|.:|..|.:..||...:.....::...|..::|...||         |
Mouse   229 SVLVLSPLAKNLFHRAISQSGVVFTSGLFMEDASSVTEQIAVTAGCKTTTSAVIVH--------- 284

  Fly   463 PCLRTKSVAELLAV---------------KVDHPRFLVGFAPFV-DGTVISPGANPL----GSTT 507
             |||.|:..|||.:               |.::|     |.|.| ||.|:......:    ...|
Mouse   285 -CLRQKTEEELLEIMQKMNLFKLDAQENTKKNYP-----FLPTVLDGVVLPKAPEAILAEKNFNT 343

  Fly   508 LPLGSAIVSTSGIEYANFPKRDLIFCLTSVESYLDLSAQDLEFGFNETRRD-RILRTFVRNNFHY 571
            :|.   ||   ||.     |::..:.|..:          :||...:.:.| :::..|:| ...|
Mouse   344 VPY---IV---GIN-----KQEFGWTLPMI----------MEFPPTDVKLDKKVISLFLR-KLAY 386

  Fly   572 HLN---EIFAVLKNEYTDWEKAIRNPLSSRDATLQFLSDGHTASPLIKLGYMHSLRGGRAYFLHF 633
            ..|   :...|...:|:   |...:|:.:|...||.:.|.....|.:.:...|...|...|...|
Mouse   387 FFNIPEDGIPVAIEKYS---KGTDDPIQNRVWLLQLIGDVMFGIPSVIVSRGHRDAGAPTYMYEF 448

  Fly   634 ----------KHKTIEEEYPQRSGSVRGEDVPFWLGLPMSPLFPHNYTTQERQIGRLMLRYLSNF 688
                      |.||:..::.....||.|           :|:.....:.:|..:.::|:::.:||
Mouse   449 QSRPSFSSELKPKTVTGDHGDEVYSVFG-----------APILREGSSEEEINLSKMMMKFWANF 502

  Fly   689 AKTGNPNQSTAKSVLPNPNEVLETALHQQKKRSTSLTHPNLSEALNLAVLYNQRRSNAMHEKRSY 753
            |:.||||...    ||:..|                              |||        |:.|
Mouse   503 ARNGNPNGQG----LPHWPE------------------------------YNQ--------KKGY 525

  Fly   754 IRRRLRSNDAAFTQLGISSERDVGSYDGDELPFW 787
            :            |:|.::::..|..| .|:..|
Mouse   526 L------------QIGATTQQAQGLKD-KEVSLW 546

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg2	NP_523496.1	COesterase	182..729	CDD:395084	164/596 (28%)
Ces1h	NP_001357759.1	COesterase	22..546	CDD:395084	177/665 (27%)