Protein Alignment Nlg2 and Ces2g

DIOPT Version :10

• Sequence 1: NP_523496.1
• Gene: Nlg2 / 33962
• FlyBaseID: FBgn0031866
• Length: 1248
• Species: Drosophila melanogaster
• Sequence 2: NP_932116.2
• Gene: Ces2g / 72361
• MGIID: 1919611
• Length: 560
• Species: Mus musculus
• Alignment Length: 725
• Identity: 183/725 - (25%)
• Similarity: 283/725 - (39%)
• Gaps: 222/725 - (30%)

  Fly   144 HYPGHSAVQPGHPEACALLVLLLLTSLWPDCCECLHGGS------NTVKTKYGLLRGIVVRSSPL 202
            |..||.:     ||...:              ...|.|.      :...||.|
Mouse    23 HVQGHDS-----PETSPI--------------RSTHSGQVQGRLIHVKDTKAG------------ 56

  Fly   203 VEAFLGIPYASPPVGSLRFMPPITPSTWKTVRSADRFSPVCPQNIPIPPNGPEALLEVPRARLAQ 267
            |..|||||:|.||||.|||.||..|..|..||.......:||||:.:...|           |.:
Mouse    57 VHTFLGIPFAKPPVGPLRFAPPEAPEPWSGVRDGTSQPAICPQNVTMNMEG-----------LKE 110

  Fly   268 LRRLLPLLKNQSEDCLYLNIYVPYETRRQRRNTDDTTGEPKTKLSTVVFIHGESYDWNSGNPYDG 332
            |:..||.: :.||||||||||.|            ...:..:.|..:|:|||.:......:.|||
Mouse   111 LKLTLPPV-SMSEDCLYLNIYTP------------AHAQEGSNLPVMVWIHGGALTVGMASMYDG 162

  Fly   333 SELAAHGNVIVVTINFRLGIFGFLKTGGKESAQGNFGLMDLVAGLHWLKENLPAFGGDPQSITLL 397
            |.|||..:|:||.|.:|||:.||..| |.|.|:||:|.:|.||.|.|:::|:..|||:|..:|:.
Mouse   163 SVLAATEDVVVVAIQYRLGVLGFFST-GDEHARGNWGFLDQVAALRWVQQNIAHFGGNPDRVTIF 226

  Fly   398 GYGTGAVLANILVVSPVASDLIQRTVLVSGSALSPWAIQKNPLFVKRRVAEQTGCHGDMLYDDLA 462
            |...|.:..:..||||::..|..|.::.||.||.|..|......|.:.||:.:||.. |..:.|.
Mouse   227 GESAGGISVSSHVVSPMSKGLFHRAIMESGVALLPGTIFSFSEVVYQTVAKLSGCEA-MDSEALV 290

  Fly   463 PCLRTKSVAELLAVK---------VD------HPRFLVGFAPFVDGTVISPGANPLGSTTLPLGS 512
            .|||.||..|:||:.         ||      ||:.|:..|.|          :|:.|
Mouse   291 RCLRGKSEEEILAISKNFQMIPGVVDGEFLPKHPQELLASADF----------HPVPS------- 338

  Fly   513 AIVSTSGIEYA-NFPKRDLIFCLTSVESYLDLSAQDLEFGFNETRRDRILRTFVRNNFHYHLNEI 576
             |:..:..||. ..||     .:.|.::...::.::|:....:|....:|..           |.
Mouse   339 -IIGFNNDEYGWIVPK-----VIGSTQTIKGITRENLQAVLKDTAPQMMLPP-----------EC 386

  Fly   577 FAVLKNEYTDWEKAIRNPLSSRDATLQFLSDGHTASPLIKLGYMHSLRGGRAYFLHFKHKT--IE 639
            ..:|..||.:   .|.:|.:.:....:.:.|.....|.:::.|..... ...||..|:|::  ::
Mouse   387 SDLLMEEYME---DIEDPKTLQIQFTEMMEDFMFVIPSLQVAYFQRSH-APVYFYEFQHQSSFLK 447

  Fly   640 EEYPQRSGSVRGEDVP------FWLGLPMSPLFPHNYTTQERQIGRLMLRYLSNFAKTGNPNQST 698
            :..|....:..|::||      || |:.:      |.|.:|:.:.|.|::|.:|||:.||||
Mouse   448 DVRPPHVNADHGDEVPFVFGSFFW-GMKL------NLTEEEKLLNRRMMKYWANFARHGNPN--- 502

  Fly   699 AKSVLPNPNEVLETALHQQKKRSTSLTHPNLSEALNLAVLYNQRRSNAMHEKRSYIRRRLRSNDA 763
                                                                             
Mouse   503 ----------------------------------------------------------------- 502

  Fly   764 AFTQLGISSERDVGSYDGDELPFWDAYDVVNQLYVELGNKANIQSHYRGHKLSMWLNLIP----Q 824
                             .:.||:|..:|...| |::|..:..:....:..||..|...:|    :
Mouse   503 -----------------SESLPYWPVFDHDEQ-YLQLNIQPAVGQFQKARKLQFWTKTLPRKIEE 549

  Fly   825 LHRHFNINDQ 834
            |.|..|::.:
Mouse   550 LKRSQNVHKE 559

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg2	NP_523496.1	COesterase	182..729	CDD:395084	162/576 (28%)
Ces2g	NP_932116.2	COesterase	33..539	CDD:395084	173/688 (25%)