Protein Alignment Nlg2 and Ces2f

DIOPT Version :9

• Sequence 1: NP_001245916.1
• Gene: Nlg2 / 33962
• FlyBaseID: FBgn0031866
• Length: 1248
• Species: Drosophila melanogaster
• Sequence 2: NP_001073334.2
• Gene: Ces2f / 71903
• MGIID: 1919153
• Length: 561
• Species: Mus musculus
• Alignment Length: 705
• Identity: 190/705 - (26%)
• Similarity: 278/705 - (39%)
• Gaps: 210/705 - (29%)

  Fly   158 ACALLVLLL-LTSLWPDCCECLHGGSNTVKTKYGLLRGIVVRSSPL---VEAFLGIPYASPPVGS 218
            ||.|||||| :..|  |..|    .|....|..|.:||..|..:.:   ...|||||:|.||||.
Mouse    14 ACGLLVLLLHVKGL--DSSE----ASPIRNTHTGQVRGKFVHLTDIKAGAHNFLGIPFAKPPVGP 72

  Fly   219 LRFMPPITPSTWKTVRSADRFSPVCPQNIPIPPNGPEALLEVPRARLAQLRRLLPLLKNQSEDCL 283
            |||.||..|..|..||.......:|.||..|          |....|..::.:||.. :.|||||
Mouse    73 LRFAPPEAPEPWSGVRDGTSQPAMCLQNDDI----------VNLEGLKIIKMILPPF-SMSEDCL 126

  Fly   284 YLNIYVPYETRRQRRNTDDTTGEPKTKLSTVVFIHGESYDWNSGNPYDGSELAAHGNVIVVTINF 348
            |||||.|            ...:..:.|..:|::||........:.||||.|||..:|:||...:
Mouse   127 YLNIYTP------------AHAQEGSNLPVMVWLHGGGLVAGMASMYDGSVLAATEDVVVVVTQY 179

  Fly   349 RLGIFGFLKTGGKESAQGNFGLMDLVAGLHWLKENLPAFGGDPQSITLLGYGTGAVLANILVVSP 413
            ||||.||..| |.|.|:||:|.:|..|.|||:::|:..|||:|.|:||.|...|....:..|:||
Mouse   180 RLGIPGFYST-GDEQARGNWGFLDQTAALHWVQQNIANFGGNPDSVTLFGQSAGGTSVSFHVLSP 243

  Fly   414 VASDLIQRTVLVSGSALSPWAIQKNPLFVKRRVAEQTGCHGDMLYDDLAPCLRTKSVAELLAVK- 477
            |:..|..|.::.||.||.|..|..:|..:..:||..:||.... .:.|..|||.||.||:||:.
Mouse   244 VSQGLFHRAIMESGVALLPTIIPDSPEMIFTKVANLSGCETSN-SEALVRCLRGKSEAEILAMSK 307

  Fly   478 --------VD------HPRFLVGFAPFVDGTVISPGANPLGSTTLPLGSAIVSTSGIEYA-NFPK 527
                    ||      ||:.|:..|.|          :|:.|        |:..:..||. ..||
Mouse   308 AFRFMPAVVDGKFLPRHPKKLLASADF----------HPVPS--------IIGVNNDEYGWIIPK 354

  Fly   528 RDLIFCLTSVESYLDLSAQDLEFGFNETRRDRILRTFVRNNFHYHLNEIFAV------LKNEYTD 586
                                 .|.|::|     :|...|||    |..|..:      |.:|..|
Mouse   355 ---------------------IFKFSQT-----IRKINRNN----LKAIMKITTEQMMLPSECGD 389

  Fly   587 W--EKAIRNPLSSRDATLQF---LSDGHTASPLIKLGYMHSLRGGRAYFLHFKHKTIEEEY--PQ 644
            .  |:.:|:........:||   :.|.....|.:::....... ...||..|:|::...:|  |.
Mouse   390 LLIEEYLRDTEDPWTLQMQFREMIGDFLIIIPALQVARFQRSH-APVYFYEFQHRSSLLKYFRPW 453

  Fly   645 RSGSVRGEDV-----PFWLGLPMSPLFPHNYTTQERQIGRLMLRYLSNFAKTGNPNQSTAKSVLP 704
            ...:..|:::     .|:.||..|      :|.:|:.:.|.|::|.:|||:.||||
Mouse   454 HVKADHGDELYLIFGSFFWGLKFS------FTAEEKLLSRKMMKYWANFARYGNPN--------- 503

  Fly   705 NPNEVLETALHQQKKRSTSLTHPNLSEALNLAVLYNQRRSNAMHEKRSYIRRRLRSNDAAFTQLG 769
                                                                             
Mouse   504 ----------------------------------------------------------------- 503

  Fly   770 ISSERDVGSYDGDELPFWDAYDVVNQLYVELGNKANIQSHYRGHKLSMWLNLIPQ 824
                       .::||:|.|.: .:.||::|....::....:..:|..|...:||
Mouse   504 -----------SEDLPYWPASN-QDDLYLQLDIHPSVGHALKARRLPFWTKTLPQ 546

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg2	NP_001245916.1	COesterase	182..712	CDD:278561	168/566 (30%)
Ces2f	NP_001073334.2	COesterase	32..540	CDD:395084	176/673 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810