Protein Alignment Nlg2 and ces2a

DIOPT Version :10

• Sequence 1: NP_523496.1
• Gene: Nlg2 / 33962
• FlyBaseID: FBgn0031866
• Length: 1248
• Species: Drosophila melanogaster
• Sequence 2: NP_001070720.1
• Gene: ces2a / 566132
• ZFINID: ZDB-GENE-061013-99
• Length: 555
• Species: Danio rerio
• Alignment Length: 566
• Identity: 167/566 - (29%)
• Similarity: 243/566 - (42%)
• Gaps: 107/566 - (18%)

  Fly   188 KYGLLRG--IVVRSSP-LVEAFLGIPYASPPVGSLRFMPPITPSTWKTVRSADRFSPVCPQNIPI 249
            |:|.:||  :..:.|| :||.:||||:|.||||..|...|.....|:.:|:|.....:|.||..|
Zfish    32 KHGSVRGQYVKAKGSPAVVEQYLGIPFAQPPVGPHRLAAPQPVQGWEGIRNATEHPLMCLQNPDI 96

  Fly   250 PPNGPEAL-LEVPRARLAQLRRLLPLLKNQSEDCLYLNIYVPYETRRQRRNTDDTTGEPKTKLST 313
            .|...:|: |||....:             ||||||||:|.|    .||..::        ||..
Zfish    97 LPAIAKAIDLEVTAIGV-------------SEDCLYLNVYTP----SQRAESE--------KLPV 136

  Fly   314 VVFIHGESYDWNSGNP------YDGSELAAHGNVIVVTINFRLGIFGFLKTGGKESAQGNFGLMD 372
            :::|||..........      |||:.|||:..|:||.|.:||||.|:..| |.:.|:||:|.:|
Zfish   137 MIWIHGGGLAMGGACMFKELCLYDGTPLAAYEKVVVVVIQYRLGILGYFST-GDQHAKGNWGFLD 200

  Fly   373 LVAGLHWLKENLPAFGGDPQSITLLGYGTGAVLANILVVSPVASDLIQRTVLVSGSALSPWAIQK 437
            .:|.|.|:::|:.||||||||:|:.|...|.:.|::|.:||:...|.||.:..||.|.......|
Zfish   201 QIAALQWVQQNIEAFGGDPQSVTIAGESAGGISASLLTLSPMTKGLFQRAIFQSGVATVKGYFVK 265

  Fly   438 NPLFVKRRVAEQTGCHGDMLYDD-LAPCLRTKSVAELLAVKVDHPRFLVGFAP--FVDGTVISPG 499
            :|....:.:|..|.|  |....: |..|:|  .:.|...:|....:   |..|  .|||..|.
Zfish   266 DPSTHAQVIANITEC--DFSSSEVLVKCIR--EMTEEQIIKAAQKK---GIFPGAAVDGEFIK-- 321

  Fly   500 ANP---LGSTTLPLGSAIVSTSGIEYA-NFPKRDLIFCLTSVESYLDLSAQDLEFGFNETRRDRI 560
            |.|   |.|........::.|:..|:. ..|:   ||........:|..|.....|.
Zfish   322 AQPEEILKSKDFQKVPILIGTTNHEFGWMLPQ---IFLPKEWVKGMDTKAAKDRLGL-------- 375

  Fly   561 LRTFVRNNFHYHLNEIFA-----VLKNEYTDWEKAIRNPLSSRDATLQFLSDGHTASPLIKLGYM 620
                        ||...|     ::.:||.   |..:.|...|||..:.|.|.....|.|.:...
Zfish   376 ------------LNADGASGANGIIADEYF---KNAKTPEEIRDAFTELLGDIFMVIPSITVASY 425

  Fly   621 HSLRGGRAYFLHFKH--KTIEEEYPQRSGSVRGEDVP------FW------LGLPMSPLFPHNYT 671
            |...|...|...|:|  .|..:..|....:...:||.      ||      ||         ..|
Zfish   426 HREAGVPVYMYEFQHGPSTANKFRPSFVKADHADDVGFVFGACFWDVHVKGLG---------TLT 481

  Fly   672 TQERQIGRLMLRYLSNFAKTGNPNQSTAK-SVLPNPNEVLETALHQ 716
            .:|.|:.|.:::|.:||.:||:||.:... .|....|:.|...|.|
Zfish   482 EEENQLCRTVMKYRANFIRTGSPNPAPVPWPVYDQSNKYLNLGLQQ 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg2	NP_523496.1	COesterase	182..729	CDD:395084	167/566 (30%)
ces2a	NP_001070720.1	COesterase	25..541	CDD:395084	167/566 (30%)