Protein Alignment Nlg2 and ces3

DIOPT Version :9

• Sequence 1: NP_001245916.1
• Gene: Nlg2 / 33962
• FlyBaseID: FBgn0031866
• Length: 1248
• Species: Drosophila melanogaster
• Sequence 2: NP_001038401.1
• Gene: ces3 / 560651
• ZFINID: ZDB-GENE-030131-9563
• Length: 549
• Species: Danio rerio
• Alignment Length: 578
• Identity: 174/578 - (30%)
• Similarity: 263/578 - (45%)
• Gaps: 85/578 - (14%)

  Fly   161 LLVLLLLTSLWPDCCECLHGGSNTVKTKYGLLRG--IVVRSSP-LVEAFLGIPYASPPVGSLRFM 222
            |.:.|.:..:|  |..........|..|:|.:||  :..:.|| :||.:||||:|.||||..|..
Zfish     7 LCLCLFVAPIW--CAPVKEDSGPVVVLKHGSVRGQYVKAKGSPAVVEQYLGIPFAQPPVGPHRLA 69

  Fly   223 PPITPSTWKTVRSADRFSPVCPQNIPIPPNGPEAL-LEVPRARLAQLRRLLPLLKNQSEDCLYLN 286
            .|.....|:.:|:|..:|.:|.|:..|.|...::: ||:|...:             ||||||||
Zfish    70 APQPVQGWEGIRNATEYSSMCLQDPNIVPKYAKSMTLELPPTGV-------------SEDCLYLN 121

  Fly   287 IYVPYETRRQRRNTDDTTGEPKTKLSTVVFIHGESYDWNSGNPYDGSELAAHGNVIVVTINFRLG 351
            :|.|    .||..:|        |...:|:|||.:........|||:.|||:..|:||.|.:|||
Zfish   122 VYTP----SQRSESD--------KFPVMVWIHGGALVIGGACMYDGTPLAAYEKVVVVVIQYRLG 174

  Fly   352 IFGFLKTGGKESAQGNFGLMDLVAGLHWLKENLPAFGGDPQSITLLGYGTGAVLANILVVSPVAS 416
            |.|:|.| |.:.||||:|.:|.:|.|.|:::|:.||||||||:|:.|...|.:.|::|.:||:..
Zfish   175 ILGYLST-GDQHAQGNWGFLDQIAALQWVQQNIEAFGGDPQSVTIAGESAGGISASLLTLSPMTK 238

  Fly   417 DLIQRTVLVSGSALSPWAIQKNPLFVKRRVAEQTGCHGDMLYDD-LAPCLRTKSVAELLAVKVDH 480
            .|.||.:..||.|.......|:||...:.:|..|.|  |....: |..|:|  .:.|...:|...
Zfish   239 GLFQRAIFQSGVATVKGYSFKDPLTYAKVIANITEC--DFSSSEVLVKCIR--EMTEEQIIKAAQ 299

  Fly   481 PRFLVGFAPFVDGTVISPGANP---LGSTTLPLGSAIVSTSGIEY------ANFPKRDLIFCLTS 536
            .::.:..|. |||..|.  |.|   |.|...|....:|.|:..|:      |..||        .
Zfish   300 KKYRLPGAT-VDGEFIK--AQPEEILKSKDFPKIPILVGTTNHEFGWTLSHAILPK--------D 353

  Fly   537 VESYLDLSA--QDLEFGFNETRRDRILRTFVRNNFHYHLNEIFAVLKNEYTDWEKAIRNPLSSRD 599
            ....:|..:  |.|:|.:|.                 ..:|...::.:||.   |..:.|...||
Zfish   354 WAKGMDAKSAKQTLDFFYNA-----------------GASEANGIIADEYF---KNAKTPEEIRD 398

  Fly   600 ATLQFLSDGHTASPLIKLGYMHSLRGGRAYFLHFKH-KTIEEEY-PQRSGSVRGEDVPFWLGLPM 662
            |..:.|.|.....|.||:...|...|...|...|:| .:|..:: |....:..|:::.|..|...
Zfish   399 AFTELLGDIIMVIPSIKVASYHRDAGAPVYMYEFQHGPSIANKFRPSFVKADHGDEIGFMFGACF 463

  Fly   663 ---SPLFPHNYTTQERQIGRLMLRYLSNFAKTGNPNQSTAK-SVLPNPNEVLETALHQ 716
               ........|.:|.|:.|.:::|.:||.:||:||.:... .|....|:.|...|.|
Zfish   464 WDGQVKVTGTLTEEENQLCRTVMKYWANFVRTGSPNPAPVPWPVYDQSNKYLNLGLQQ 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg2	NP_001245916.1	COesterase	182..712	CDD:278561	168/551 (30%)
ces3	NP_001038401.1	COesterase	24..535	CDD:278561	170/559 (30%)
		Aes	<122..>235	CDD:223730	51/125 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910