Protein Alignment Nlg2 and Ces2h

DIOPT Version :9

• Sequence 1: NP_001245916.1
• Gene: Nlg2 / 33962
• FlyBaseID: FBgn0031866
• Length: 1248
• Species: Drosophila melanogaster
• Sequence 2: NP_001258974.1
• Gene: Ces2h / 436059
• MGIID: 3648740
• Length: 558
• Species: Mus musculus
• Alignment Length: 722
• Identity: 177/722 - (24%)
• Similarity: 278/722 - (38%)
• Gaps: 219/722 - (30%)

  Fly   159 CALLVLLLLTSLWPDCCECLHGGSNTVKTKY-GLLRGIVVRSSPL---VEAFLGIPYASPPVGSL 219
            |.||:||.:..         ...::.::|.: |.:.|.::....|   |.:|||||:|.||||.|
Mouse    15 CGLLLLLRVQG---------QDSTSPIRTTHTGQILGSLIHMKDLDVGVHSFLGIPFAKPPVGPL 70

  Fly   220 RFMPPITPSTWKTVRSADRFSPVCPQNIPIPPNGPEALLEVPRARLAQLRRLLPLLKNQSEDCLY 284
            ||.||..|..|..||.......:|.|:|        ..:.:...:|  |:..||... .||||||
Mouse    71 RFAPPEPPEPWGGVRDGTSHPAMCLQDI--------TAMNMQAFKL--LKLTLPPFP-MSEDCLY 124

  Fly   285 LNIYVPYETRRQRRNTDDTTGEPKTKLSTVVFIHGESYDWNSGNPYDGSELAAHGNVIVVTINFR 349
            ||||.|           |...| .:.|..:|:|||.|......:.||||.|||..||:||||.:|
Mouse   125 LNIYAP-----------DHAHE-GSNLPVMVWIHGGSLVIGMASMYDGSMLAAMENVVVVTIQYR 177

  Fly   350 LGIFGFLKTGGKESAQGNFGLMDLVAGLHWLKENLPAFGGDPQSITLLGYGTGAVLANILVVSPV 414
            ||:.||..| |.|.|:||:|.:|.||.|.||::|:..|||:|..:|:.|...|....:.|||||:
Mouse   178 LGVLGFFST-GDERARGNWGYLDQVAALRWLQQNIAYFGGNPDRVTIFGTSAGGTSVSSLVVSPM 241

  Fly   415 ASDLIQRTVLVSGSALSPWAIQKNPLFVKRRVAEQTGCHGDMLYDDLAPCLRTKSVAELLAVK-- 477
            :..|.:..::.||.||....|..:...|.:.||..:||. .:..:.|..|||.||..|::|:.
Mouse   242 SQGLFRGAIMESGVALISSLISVSSDVVYQTVANLSGCE-QVDSEALVNCLRGKSEEEIMAINKA 305

  Fly   478 -------VD------HPRFLVGFAPFVDGTVISPGANPLGSTTLPLGSAIVSTSGIEYANFPKRD 529
                   ||      ||:.|:..|.|          :|:.|        |:..:..||.
Mouse   306 FKIIPGIVDGIFLPRHPQELMASADF----------HPVPS--------IIGVNNDEYG------ 346

  Fly   530 LIFCLTSVESYLDLSAQDLEFGFNETRRDRILRTFVRNNFHYHLNEIFAVLKNEYTD--WEKAIR 592
              :.:.|..|.:|          ::...||.:              :.|:|:...|.  |...:.
Mouse   347 --WIIPSSMSMID----------SKKGMDRQM--------------VQAILQRRATQMMWPPEVS 385

  Fly   593 NPLSSR----DATLQFL--------SDGHTASPLIKLGYMHSLRGGRAYFLHFKHKT--IEEEYP 643
            :.|...    :...|||        .|.....|.:::....... ...:|..|:|:.  .::..|
Mouse   386 DLLMEEYMGDNEDPQFLQVQFKEMMKDFTFVIPALQVAQFQRSH-APVFFYEFQHRPSFFKDSKP 449

  Fly   644 QRSGSVRGEDV-----PFWLGLPMSPLFPHNYTTQERQIGRLMLRYLSNFAKTGNPNQSTAKSVL 703
            ....:..|:::     .||.|..:      ::|.:|..:.|.|::|.:|||:..|||
Mouse   450 SHVKADHGDEILFIFRSFWGGTQV------DFTEEEELLSRRMMKYWANFARQRNPN-------- 500

  Fly   704 PNPNEVLETALHQQKKRSTSLTHPNLSEALNLAVLYNQRRSNAMHEKRSYIRRRLRSNDAAFTQL 768
                                                                             
Mouse   501 ----------------------------------------------------------------- 500

  Fly   769 GISSERDVGSYDGDELPFWDAYDVVNQLYVELGNKANIQSHYRGHKLSMWLNLIPQLHRHFNIND 833
                        .:.||:|..:|...| |::|..:..:....:..:|..|...:|:  :...:.|
Mouse   501 ------------SEGLPYWPMFDQDEQ-YLQLDTQPAVGRALKTRRLQFWTKTLPE--KIQELKD 550

  Fly   834 QSMRHHQ 840
            ...||.:
Mouse   551 IEDRHKE 557

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg2	NP_001245916.1	COesterase	182..712	CDD:278561	159/569 (28%)
Ces2h	NP_001258974.1	COesterase	30..537	CDD:278561	167/674 (25%)
		Aes	<127..>230	CDD:223730	49/115 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810