Protein Alignment Nlg2 and alpha-Est2

DIOPT Version :9

• Sequence 1: NP_001245916.1
• Gene: Nlg2 / 33962
• FlyBaseID: FBgn0031866
• Length: 1248
• Species: Drosophila melanogaster
• Sequence 2: NP_001262345.1
• Gene: alpha-Est2 / 40908
• FlyBaseID: FBgn0015570
• Length: 566
• Species: Drosophila melanogaster
• Alignment Length: 618
• Identity: 151/618 - (24%)
• Similarity: 234/618 - (37%)
• Gaps: 152/618 - (24%)

  Fly   180 GGSNTVKTKYGLLRGI----VVRSSPLVEAFLGIPYASPPVGSLRFMPPITPSTWKTVRSADRFS 240
            |.:..:.||||.:||:    |....|.. ||.|||||.||||.|||..|..|..|:.|.:
  Fly    30 GHTVILDTKYGQVRGLQRKTVYDKEPYF-AFEGIPYAKPPVGDLRFRAPQPPEPWQGVLN----- 88

  Fly   241 PVCPQNIPIPPNGPEALLEVPRARLAQLRRLLPLLKNQSEDCLYLNIYVPYETRRQRRNTDDTTG 305
              |..|               |::..|...||.:::. |||||:||:||             ...
  Fly    89 --CTTN---------------RSKPMQRNMLLGIVEG-SEDCLHLNVYV-------------KAL 122

  Fly   306 EPKTKLSTVVFIHGESY------------DWNSGNPYDGSELAAHGNVIVVTINFRLGIFGFLK- 357
            :.:..|..:|:|:|..:            |:....|           |:.|.||:||...|||.
  Fly   123 KSEKPLPVIVWIYGGGFQKGEASRDIYSPDYFMKKP-----------VVFVAINYRLAALGFLSL 176

  Fly   358 TGGKESAQGNFGLMDLVAGLHWLKENLPAFGGDPQSITLLGYGTGAVLANILVVSPVASDLIQRT 422
            ...|....||.||.|.|..|.|:.:|:..|.|||.:|||:|...|:...::::.:.....|..:.
  Fly   177 KDPKLDVPGNAGLKDQVMALRWISQNIAHFNGDPNNITLMGESAGSASVHVMMTTEQTRGLFHKA 241

  Fly   423 VLVSGSALSPW--AIQKNPLFVKRRVAEQTGCHGDMLYDDLAP-----CLRTKSVAELLAVKVDH 480
            ::.||.|||.|  :...|..|   |:|:..|..||....|:..     |.|..:..:...:.:|.
  Fly   242 IMQSGCALSEWVESPDNNWAF---RLAQNLGYKGDEKDADVLSFLSKVCARQIAAIDQDVINLDE 303

  Fly   481 PRFLVGFAPFVDGTVISPGANPLGSTTLPLGSAIVSTSGIEYANFPKR--DLIFCLTSVESYLDL 543
            .|   .|..|..|.||.|...                   ::...|||  ||:......:..:.:
  Fly   304 VR---SFLLFAFGPVIEPYET-------------------DHCVVPKRHKDLLSEAWGNDIPVIV 346

  Fly   544 SAQDLE--FGFNETRRDRILRTFVRNNFH--------------------------YHLNEIFAVL 580
            .....|  |.:...|:|    .:...|||                          |..||:
  Fly   347 GGNSFEGLFSYQLVRKD----PWALKNFHNILPREVRETSSLEGQDLLVRRLKQLYFNNEM---- 403

  Fly   581 KNEYTDWEKAIRNPLSSRDA---TLQFLSDGHTASPLIKLGYMHSLRGGRAYFLHFKHKTIEEEY 642
             .|..:..:|: |..|.|..   |.:|:....:.:|.... |::.......:|..|:.....:..
  Fly   404 -QESMEMFEAL-NIFSHRQIWHDTHRFILARQSYAPKTPT-YLYRFDFDSPHFNQFRRLVCGDRI 465

  Fly   643 PQRSGSVRGEDVPF-WLGLPMSPLFPHN--YTTQERQIGRLMLRYLSNFAKTGNPNQSTAKSVLP 704
               .|....:::.: :..:..|.|...:  |.|.||.:|     ..::||.:||||.....|...
  Fly   466 ---RGVAHADELSYLFYNIIASKLDKSSMEYKTIERMVG-----MWTSFASSGNPNCPELGSAKW 522

  Fly   705 NPNEVLETALHQQKKRSTSLTHPNLSEALNLAV 737
            ...::.|.|:.:....|..|...:|.|:..|||
  Fly   523 EAVQLKENAVEKCFNISHDLEMRDLPESDCLAV 555

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg2	NP_001245916.1	COesterase	182..712	CDD:278561	141/589 (24%)
alpha-Est2	NP_001262345.1	COesterase	32..523	CDD:278561	141/582 (24%)
		Aes	<117..>221	CDD:223730	35/127 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810