Protein Alignment Nlg2 and alpha-Est6

DIOPT Version :9

• Sequence 1: NP_001245916.1
• Gene: Nlg2 / 33962
• FlyBaseID: FBgn0031866
• Length: 1248
• Species: Drosophila melanogaster
• Sequence 2: NP_524262.1
• Gene: alpha-Est6 / 40902
• FlyBaseID: FBgn0015574
• Length: 568
• Species: Drosophila melanogaster
• Alignment Length: 589
• Identity: 149/589 - (25%)
• Similarity: 224/589 - (38%)
• Gaps: 159/589 - (26%)

  Fly   174 CC------ECLHGG---SNTVKTKYGLLRGIVVRSSPL----VEAFLGIPYASPPVGSLRFMPPI 225
            ||      .|...|   |..||...|.::|  .|.|.:    ..:|.|||:|.||:|..||:...
  Fly    23 CCPGFKRFSCQSAGDADSKVVKLSVGSVKG--RRLSGIYGDEFYSFEGIPFAKPPLGKARFVASQ 85

  Fly   226 TPSTWKTVRSADRFSPVCPQNIPIPPNGPEALLEVPRARLAQLRRLLPLLKNQSEDCLYLNIYVP 290
            ....|.:...|       .|..|||              |...||...::  .||||||||:|..
  Fly    86 LADPWNSELDA-------RQERPIP--------------LQMDRRSGKVV--GSEDCLYLNVYTK 127

  Fly   291 YETRRQRRNTDDTTGEPKTKLSTVVFIHGESYDWNSGNPYD---GSELAAHGNVIVVTINFRLGI 352
            :            ..|.:..|..:|:|:|.::  .:|....   |.:.....:|:.|..|:||..
  Fly   128 H------------FNESEPPLPVMVYIYGGAF--RTGGAVKSKYGPDYLMSRDVVYVLFNYRLCS 178

  Fly   353 FGFLK-TGGKESAQGNFGLMDLVAGLHWLKENLPAFGGDPQSITLLGYGTGAVLANILVVSPVAS 416
            .|||. ..||....||.||.|.:..|.|:.:::..|.||||:|||.|...||...:.::..|.|.
  Fly   179 LGFLSMPSGKLDVPGNAGLHDQLLALQWVSQHIRNFNGDPQNITLFGESAGAASVHFMMCLPQAK 243

  Fly   417 DLIQRTVLVSGSALSPW--AIQKNPLFVKRRVAEQTGCHGDMLYDDLAPCLRTKSVAELLAVKVD 479
            .|..:.:::|||.||||  |...:.:|.  |:|...|..|......:...||..:..:|:.....
  Fly   244 GLFHKAIMMSGSMLSPWVNAPDSDGIFC--RLATSAGYEGPAEEVPILEFLRNVNAEKLIGHDFI 306

  Fly   480 HPR-----FLVGFAPFVDGTVISPGANPL---GSTTLPLGSAIVSTSGIEYANFPKRDLIFCLTS 536
            .||     ||..|||.|.|.|.:|....:   .|..:||.....|..|:.|..|.:.|..:.|..
  Fly   307 SPRDRCFGFLNPFAPVVGGLVAAPFQQLMKEAWSCEVPLLLGGTSFEGLVYYPFCQLDNGYMLEL 371

  Fly   537 V----------ESYLDLSAQDLEFGFNETRRDRILR-------------TFVRNNFHYHL--NEI 576
            :          |.|..:|.::     ..|..|.:::             |.:.:.|.|.|  :.|
  Fly   372 LKHEPAMVLPHELYQSMSVEE-----RNTAADVLVKYHYGPRGITKSNITQILDLFSYKLFWHGI 431

  Fly   577 FAVLKNEYT-----------DWE----KAIRNPLSSRDATLQFLSDGHTASPLIKLGYMHSLRGG 626
            ..|:.:..:           |::    ..:||.|...|               ||.|..|:...|
  Fly   432 HRVVLSRLSHAQAPTYLYRFDFDSPKLNLMRNQLCGDD---------------IKRGVCHADDLG 481

  Fly   627 RAYFLHFKHKTIEEEYPQRSGSVRGEDVPFWLGLPMSPLFPHNYTTQERQIGRLMLRYLSNFAKT 691
            ..:     ||..:.:.|.        |.|             .:.|.:|.:|     .|:.||:|
  Fly   482 YIF-----HKQAQAKQPL--------DSP-------------EFLTIQRMVG-----ILTTFART 515

  Fly   692 GNPN 695
            |:||
  Fly   516 GDPN 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg2	NP_001245916.1	COesterase	182..712	CDD:278561	145/572 (25%)
alpha-Est6	NP_524262.1	COesterase	35..534	CDD:278561	146/577 (25%)
		Aes	<133..325	CDD:223730	61/195 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810