Protein Alignment Nlg2 and Gli

DIOPT Version :9

• Sequence 1: NP_001245916.1
• Gene: Nlg2 / 33962
• FlyBaseID: FBgn0031866
• Length: 1248
• Species: Drosophila melanogaster
• Sequence 2: NP_476602.1
• Gene: Gli / 34927
• FlyBaseID: FBgn0001987
• Length: 956
• Species: Drosophila melanogaster
• Alignment Length: 940
• Identity: 219/940 - (23%)
• Similarity: 349/940 - (37%)
• Gaps: 318/940 - (33%)

  Fly   185 VKTKYGLLRGIVV--------------------RSSPLVEAFLGIPYASPPVGSLRFMPPITPST 229
            |.|.||.::|..|                    |.......|||||||.||....||.||.....
  Fly   137 VTTNYGQVQGFKVYMYDNPDPKSFYRPYHSTVDRVMGECSVFLGIPYALPPTFEGRFKPPRVHRG 201

  Fly   230 WKTVRSADRFSPVCPQNIPIPPNG-PEALLEVPRARLAQLRRLLPLLKNQSEDCLYLNIYVPYET 293
            |:.:::.| |.|.|||  |:...| .:.::::                  .|||||||:|
  Fly   202 WQLLQAVD-FGPACPQ--PVRYTGATKGIMDM------------------DEDCLYLNVY----- 240

  Fly   294 RRQRRNTDDTTGEPKT------KLSTVVFIHGESYDWNSGNPYDGSELAAHGNVIVVTINFRLGI 352
                        .|||      |...:|:|||..:...:.|.:.|..||:..:|:|||:|:|||.
  Fly   241 ------------SPKTGAGVAQKYPVMVYIHGGEFIRGASNLFQGHILASFYDVVVVTLNYRLGA 293

  Fly   353 FGFLKTGGKESAQGNFGLMDLVAGLHWLKENLPAFGGDPQSITLLGYGTGAVLANILVVSPVASD 417
            .|||.| |.|::.||:|::|....|.|:.:|:..|.||..||||.|.|.|...|.:|:|:|...:
  Fly   294 LGFLST-GDENSPGNYGILDQAMALRWVYDNIEFFNGDRNSITLFGPGAGGASAGLLMVAPQTRN 357

  Fly   418 LIQRTVLVSGSALSPWAIQKNPLFVK---RRVAEQTGCHGDMLYDDLAPCLRT-KSVAELLAVKV 478
            :::|.:..|||||:.||:.::....:   |.:.:..||..:..: .|..|||| :|..||
  Fly   358 IVRRVIAQSGSALADWALIQDKYRAQNTSRVLGQLLGCSIESSW-KLVNCLRTGRSFYEL----- 416

  Fly   479 DHPRFLVGFAPFVDGTVISP--GANPLG-----STTLPLGSAIVSTSGIE-YANFPKRDLIFCLT 535
                   |.|.|      ||  |:.|.|     :.|||         |.: |..:.::|..|...
  Fly   417 -------GNAEF------SPQVGSFPWGPVLDHNFTLP---------GDDWYEGWREKDWRFLTQ 459

  Fly   536 SVESYL-------------DLSAQDLEF--GFNETRR----------DRILRTFV-RNNFHYHLN 574
            :.|:.:             .::.|:..|  ..||:..          |:.:|..| |.|:..:.|
  Fly   460 TPETLIRAGKFNRNIQYMTGVTTQEAAFFVAQNESLSPYYELDGRFFDQKIREHVFRYNYTLNPN 524

  Fly   575 EIFAVLKNEYTDWEKAIRNPLSSRDATLQFLSDGHTASP---LIKLGYMHSLRGGRAYFLHFKHK 636
            .::..:|..||.|.....|.: .||..:..|||.:..:|   ::||    .|......:::..:.
  Fly   525 GVYEAIKYIYTFWPDPNNNTI-IRDQYINMLSDLYYRAPVDQMVKL----MLEQKVPVYMYVLNT 584

  Fly   637 TIE-------EEYPQRSGSVRGEDVP--FWLGLPM--SPLFP-------HNYTTQERQIGRLMLR 683
            |:|       .:||        .|:.  |..|.|.  :..||       :.:|..:|.:....::
  Fly   585 TVEALNLPQWRKYP--------HDIERYFLTGAPFMDTEFFPKKEHLQRNMWTDNDRNMSHFFMQ 641

  Fly   684 YLSNFAKTGNPNQSTAKSVLPNPNEVLETALHQQKKRSTSLTHPNLSEALNLAVLYNQRRSNAMH 748
            ..:|||:.||          |.|.:||  .:|.|:.....:.:.|::...|.::|.|.|::
  Fly   642 TYTNFARYGN----------PTPQQVL--GMHFQRAYQGEIRYLNINTTYNSSILLNYRQT---- 690

  Fly   749 EKRSYIRRRLRSNDAAF------TQLGISSERDVGSYDGDELPFWDAYDVVNQLYVELGNKANIQ 807
                         :.||      |.:|:.    |.:|......:|:.             |..:|
  Fly   691 -------------ECAFWTQYLPTVIGVL----VPTYPPTTEYWWEP-------------KEPLQ 725

  Fly   808 SHYRGHKLS-------------MWLNLIPQLHRHFN----INDQSM----------------RHH 839
            ..:....::             ||.|...|..|.::    ||.:.:                .||
  Fly   726 IAFWSMSVACFFLIVLVVICCIMWRNAKRQSDRFYDEDVFINGEGLEPEQDTRGVDNAHMVTNHH 790

  Fly   840 QFQDDMNNRD-LYEGVVRPQLQT-------------KPA---------------------EDDNI 869
            .    :.:|| :||....|..:|             .|:                     |.:..
  Fly   791 A----LRSRDNIYEYRDSPSTKTLASKAHTDTTSLRSPSSLAMTQKSSSQASLKSGISLKETNGH 851

  Fly   870 IIMQRSRTTTPPPPSK-------NPSTNATQALNPLGTGTPTT-----------TECGIDGAMSV 916
            ::.|..|..||.....       :|.....:.|.|| :.||.|           |...:.|
  Fly   852 LVKQSERAATPRSQQNGSTAKVASPPVEEKRLLQPL-SSTPVTQLQAEPAKRVPTAASVSG---- 911

  Fly   917 SELTTTQSPKDNRTGIVRVETQKDLATAST 946
            |..:||..|....|     .|....||.|:
  Fly   912 SSRSTTPVPSARST-----TTHTTTATLSS 936

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg2	NP_001245916.1	COesterase	182..712	CDD:278561	164/612 (27%)
Gli	NP_476602.1	COesterase	134..695	CDD:278561	172/666 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D80457at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR43903
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.920