Protein Alignment Nlg2 and LOC3291355

DIOPT Version :10

• Sequence 1: NP_523496.1
• Gene: Nlg2 / 33962
• FlyBaseID: FBgn0031866
• Length: 1248
• Species: Drosophila melanogaster
• Sequence 2: XP_557411.3
• Gene: LOC3291355 / 3291355
• VectorBaseID: AGAMI1_002579
• Length: 559
• Species: Anopheles gambiae
• Alignment Length: 701
• Identity: 176/701 - (25%)
• Similarity: 270/701 - (38%)
• Gaps: 209/701 - (29%)

  Fly   159 CALLVL--LLLTSLWPDCC----ECLHGGSNTVKTKYGLLRGIVVRSSPLVEAFLGIPYASPPVG 217
            ||:|:|  ..::|:..:|.    :...|...|..|         ..|:|.. |:.|:.|..||.|
Mosquito     4 CAVLLLCHFFISSVQANCLVQYEQAATGVGETKAT---------FNSTPYC-AYYGVRYGEPPTG 58

  Fly   218 SLRFMPPIT--PSTWKTVRSADRFSP--VCPQ-NIPIPPN---GPEALLEVPRARLAQLRRLLPL 274
            ||||...|.  ||     .|.:..:|  ||.| |.|...:   |
Mosquito    59 SLRFRHSIVHQPS-----GSLNYTTPGSVCAQYNNPFTRDFVIG--------------------- 97

  Fly   275 LKNQSEDCLYLNIYVPYETRRQRRNTDDTTGEPKTKLSTVVFIHGESYDWNSG-NPYDGSELAAH 338
                |||||:.|||.|    |.:.:|:      ......:||:||.||....| ...:|::|...
Mosquito    98 ----SEDCLFANIYTP----RVKESTE------AAAYPVLVFVHGGSYAVGHGEKDINGADLLID 148

  Fly   339 GNVIVVTINFRLGIFGFLKTGGKESAQGNFGLMDLVAGLHWLKENLPAFGGDPQSITLLGY--GT 401
            ..|:|||.|:||.:.||||| .|.:..|||||.|....|.|::..:..|||||..:||||:  |.
Mosquito   149 SGVVVVTFNYRLNVLGFLKT-NKFNISGNFGLKDQTTLLRWVQRYIGNFGGDPAQVTLLGHSAGA 212

  Fly   402 GAVLANILVVSPVASDLIQRTVLVSGSALSPWAIQKNP----------LFVKRRVAEQTGCHGDM 456
            |:|..::.:  |.:.||..|.:::|||.|:.|:...||          |..|..|..:|....|.
Mosquito   213 GSVTHHLYI--PQSKDLFHRVIVLSGSLLASWSFMYNPRLCTESYLSDLQPKTAVEFRTRAVEDF 275

  Fly   457 LYDD------------LAPCLRTKSVAELLAVKVDHPRFLVGFAPFVDGTVISPGANPLGSTTLP 509
            ...:            ..|||    :.||...:::...:.|. ||.|  :|:||   |:  |.:|
Mosquito   276 FIQNGTTGFAFGFASMGTPCL----IPELEQEEIERDNYTVN-APHV--SVLSP---PI--TKVP 328

  Fly   510 LGSAIVSTSGIEYANFPKRDLIFCLTSVESYLDLSAQDLEFGFNETRRDRILRTFVRNNFHYHLN 574
            :   ::|.:..|:.:..|            :||        ||      |......:|.....:.
Mosquito   329 I---LISETAREFVDQLK------------HLD--------GF------RFYPNIPQNWTAQKVG 364

  Fly   575 EIFAVLKNEYTDWEKAIRNPLSSRDATLQFLSDGHTASPLIKLG--YMHSLRGGR-AYFLHFKH- 635
            .:.:.:.| :|....|..:..||.:...|.....:...|:.:|.  ...:|.|.. .|:|.|:.
Mosquito   365 ALISFVHN-FTSQLVAAGHVNSSEEVFQQIADVANLRYPMRRLAQDLAQTLHGTMPVYYLRFEFD 428

  Fly   636 ----KTIEEEY-----PQRSGSVRGEDVPFWLGLPMSP------LFPHNYTTQERQIGRLMLRYL 685
                |...:||     ..:.|::.|:|    ||...||      |...:...:|.:|.|..:..:
Mosquito   429 GQFGKAKYKEYISYLPNSQYGAIHGDD----LGYIFSPYNLEEALAKADQYREEWRIHRWTVELI 489

  Fly   686 SNFAKTGNPNQSTAKSVLPNPNEVLETALHQQKKRSTSLTHPNLSEALNLAVLYNQRRSNAMHEK 750
            :||.|.|||.        |.|:          |..:.:.|..|
Mosquito   490 ANFIKHGNPT--------PTPS----------KLSNITWTPWN---------------------- 514

  Fly   751 RSYIRRRLRSNDAAFTQLGISSERDVGSYDGDEL-PFWDAYDVVNQLYVEL 800
                     .||:|...|.|....|:..:..|.: .||  .:|.|.||.::
Mosquito   515 ---------GNDSANPYLNIDKTFDMREFKDDRIFRFW--AEVYNCLYYKV 554

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg2	NP_523496.1	COesterase	182..729	CDD:395084	155/598 (26%)
LOC3291355	XP_557411.3	None