Protein Alignment Nlg2 and Ces5a

DIOPT Version :10

• Sequence 1: NP_523496.1
• Gene: Nlg2 / 33962
• FlyBaseID: FBgn0031866
• Length: 1248
• Species: Drosophila melanogaster
• Sequence 2: NP_001012056.2
• Gene: Ces5a / 307660
• RGDID: 1549717
• Length: 575
• Species: Rattus norvegicus
• Alignment Length: 674
• Identity: 173/674 - (25%)
• Similarity: 269/674 - (39%)
• Gaps: 201/674 - (29%)

  Fly   187 TKYGLLRG----IVVRSSPLVEAFLGIPYASPPVGSLRFMPPITPSTWKTVRSADRFSPVCPQNI 247
            |:.|.::|    ::.|..| |..|||||:|:||:|.|||..|..|..|..:|.|..:..||.||:
  Rat    35 TRLGWVQGKQATVLGRLEP-VNVFLGIPFAAPPLGPLRFSNPQPPIPWHDLREATTYPNVCFQNL 98

  Fly   248 P---IPPNGPEALLEVPRARLAQLRRLLPLLKNQSEDCLYLNIYVPYETRRQRRNTDDTTGEPKT 309
            .   |..|    ||:|...:|           ..||||||||||.|            ......:
  Rat    99 EWLFIYQN----LLKVHYPKL-----------GVSEDCLYLNIYAP------------AYANDGS 136

  Fly   310 KLSTVVFIHGESYDWNSGNPYDGSELAAHGNVIVVTINFRLGIFGFLKTGGKESAQGNFGLMDLV 374
            :|..:::|.|..::..|.:.:|||.|||:.:|::|||.:|||||||..| ..:.|.||:...|.:
  Rat   137 RLPVMMWIPGGGFETGSASIFDGSALAAYEDVLIVTIQYRLGIFGFFNT-QNQHAPGNWAFQDQL 200

  Fly   375 AGLHWLKENLPAFGGDPQSITLLGYGTGAVLANILVVSPVASDLIQRTVLVSGSALSPWAIQ--- 436
            |.|.|::||:..|||:|.|:|:.|...||:..:.|::||:::.|..|.::.||.|:.| :::
  Rat   201 AALQWVRENINYFGGNPDSVTIFGGSAGAISISSLILSPLSAGLFHRAIMQSGVAIIP-SLKNFD 264

  Fly   437 ---KNPLFVKRRVAEQTGCHGDMLYDD--LAPCLRTKSVAELLAVKVDHPRFLVGFAPFVDGTVI 496
               |:.|.|   ||:...|:   :.|.  |..|||.||..|||::    .:....|...|||:..
  Rat   265 DELKHGLQV---VADVCKCN---VSDSKVLLKCLREKSSLELLSL----GQKTKAFTRVVDGSFF 319

  Fly   497 SPGANP---LGSTTLPLGSAIVSTSGIEYAN-FPKRDLIFCLTSVESYLDLSAQDLEFGFNETRR 557
            .  ..|   |...|.....:|:..:..|... .|.|:               |.::.||.||:..
  Rat   320 P--EEPMELLSQKTFKTVPSIIGVNNQECGYILPMRE---------------APEILFGSNESTA 367

  Fly   558 DRILRTFV-----------RNNFHYHLNEIFAVLKNEYTDWEKAIRNPLSSRDATLQFLSDGHTA 611
            ..::...:           ::.||.         |:..||          .||..|....|....
  Rat   368 LTLIHVLLHIPPQYMHIVAKDYFHG---------KHSLTD----------IRDTLLDLFGDVFFV 413

  Fly   612 SPLIKLGYMHSLRGGRAYFLHFKHK--TIEEEYPQRSGSVRGEDVPFWLGLPM---SPLFPHNYT 671
            .|.:.....|...||..||..|:|:  ..:...|....:...:::.|..|.|.   ..:.....|
  Rat   414 VPGLVTARNHRDAGGPVYFYEFQHRPNCFQNTRPAFVKADHTDEIRFVFGGPFLEGDVVMFEEAT 478

  Fly   672 TQERQIGRLMLRYLSNFAKTGNPNQSTAKSVLPNPNEVLETALHQQKKRSTSLTHPNLSEALNLA 736
            ..|:.:.|.|:.|.:|||::|:||
  Rat   479 EDEKLLSRKMMSYWANFARSGDPN----------------------------------------- 502

  Fly   737 VLYNQRRSNAMHEKRSYIRRRLRSNDAAFTQLGISSERDVGSYDGDELPFWDAYDVVNQLYVELG 801
                                                        ||:||.|.||| .|:.|::|
  Rat   503 --------------------------------------------GDDLPLWPAYD-QNESYLKL- 521

  Fly   802 NKANIQSHYR--GHKLSMWLNLIP 823
             ..||.:.:|  ..::..|.:.:|
  Rat   522 -DVNISTGWRLKDRRVEFWTDTLP 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg2	NP_523496.1	COesterase	182..729	CDD:395084	157/576 (27%)
Ces5a	NP_001012056.2	COesterase	29..539	CDD:395084	171/667 (26%)