Protein Alignment Nlg2 and Ces2g

DIOPT Version :9

• Sequence 1: NP_001245916.1
• Gene: Nlg2 / 33962
• FlyBaseID: FBgn0031866
• Length: 1248
• Species: Drosophila melanogaster
• Sequence 2: NP_001099645.1
• Gene: Ces2g / 291952
• RGDID: 1308358
• Length: 560
• Species: Rattus norvegicus
• Alignment Length: 679
• Identity: 172/679 - (25%)
• Similarity: 271/679 - (39%)
• Gaps: 188/679 - (27%)

  Fly   187 TKYGLLRGIVVRSSPL---VEAFLGIPYASPPVGSLRFMPPITPSTWKTVRSADRFSPVCPQNIP 248
            |..|.::|.:..|...   |..|||||:|..|||.|||.||..|..|..||.....|.:||||:.
  Rat    38 THTGQVQGKLTHSKDFKSGVHTFLGIPFAKAPVGPLRFAPPEAPEPWSGVRDGTSQSNICPQNVR 102

  Fly   249 IPPNGPEALLEVPRARLAQLRRLLPLLKNQSEDCLYLNIYVPYETRRQRRNTDDTTGEPKTKLST 313
            :...|           |.:::..||.: :.||||||||||.|.....            .:.|..
  Rat   103 MNMEG-----------LKEMKLTLPPV-SMSEDCLYLNIYAPAHAHE------------GSHLPV 143

  Fly   314 VVFIHGESYDWNSGNPYDGSELAAHGNVIVVTINFRLGIFGFLKTGGKESAQGNFGLMDLVAGLH 378
            :|:|||.:......:.||||.|||..:|:||||.:|||:.||..| |...|:||:|.:|.||.|.
  Rat   144 MVWIHGGALTVGMASMYDGSMLAATEDVVVVTIQYRLGVLGFFST-GDHHARGNWGYLDQVAALR 207

  Fly   379 WLKENLPAFGGDPQSITLLGYGTGAVLANILVVSPVASDLIQRTVLVSGSALSPWAIQKNPLFVK 443
            |:::|:..|||:|..:|:.|...|.:..:..||||::..|..|.::.||.||.|..|......|.
  Rat   208 WVQQNIAHFGGNPDCVTIFGESAGGLSVSSHVVSPMSKGLFHRAIMESGVALMPGTIFNFSEMVY 272

  Fly   444 RRVAEQTGCHGDMLYDDLAPCLRTKSVAELLAVK---------VD------HPRFLVGFAPFVDG 493
            :.|.:.:||.. |..:.|..|||.||..::..:.         ||      ||:.|:..|.|
  Rat   273 QMVVKLSGCEA-MDPESLVHCLRGKSEEQITVISKEFQMIPAVVDGEFLPNHPQELLASADF--- 333

  Fly   494 TVISPGANPLGSTTLPLGSAIVSTSGIEYA-NFPKRDLIFCLTSVESYLDLSAQDLEFGFNETRR 557
                   :|:.|        |:..:..||. ..||     .:.|.::...::.::|:....:|..
  Rat   334 -------HPVPS--------IIGFNNDEYGWIVPK-----VIGSAQTIKGITRENLQAFLKDTAP 378

  Fly   558 DRILRTFVRNNFHYHLNEIFAVLKNEYTDWEKAIRNPLSSRDATLQFLSDGHTASPLIKLGYMHS 622
            ..:|..           |...:|..||..   .|.:|.:.:....:.:.|.....|.:::.....
  Rat   379 QMMLPP-----------ECSDLLMEEYMG---DIEDPQTLQAQFTEMMEDFMFVIPSLQVARFQR 429

  Fly   623 LRGGRAYFLHFKHKT--IEEEYPQRSGSVRGEDVP------FWLGLPMSPLFPHNYTTQERQIGR 679
            .. ...||..|:|::  :::..|....:..|::||      || |:.:      |.|..|:.:.|
  Rat   430 SH-APVYFYEFQHQSSFLKDIRPPHVKADHGDEVPFVFGSFFW-GMKL------NLTEGEKLLNR 486

  Fly   680 LMLRYLSNFAKTGNPNQSTAKSVLPNPNEVLETALHQQKKRSTSLTHPNLSEALNLAVLYNQRRS 744
            .|::|.:|||:.||||.::
  Rat   487 RMMKYWANFARYGNPNSNS---------------------------------------------- 505

  Fly   745 NAMHEKRSYIRRRLRSNDAAFTQLGISSERDVGSYDGDELPFWDAYDVVNQLYVELGNKANIQSH 809
                                                   ||:|..:|...| |::|..:..:...
  Rat   506 ---------------------------------------LPYWPVFDYDEQ-YLQLNTQPAVGRI 530

  Fly   810 YRGHKLSMWLNLIPQ----LHRHFNINDQ 834
            .:..||..|...:||    |.|..|::.:
  Rat   531 QKARKLQFWTKTLPQKIEELKRSQNMHKE 559

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg2	NP_001245916.1	COesterase	182..712	CDD:278561	157/551 (28%)
Ces2g	NP_001099645.1	COesterase	31..539	CDD:278561	166/657 (25%)
		Aes	<129..>232	CDD:223730	43/115 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810