Protein Alignment Nlg2 and Ces1c

DIOPT Version :9

• Sequence 1: NP_001245916.1
• Gene: Nlg2 / 33962
• FlyBaseID: FBgn0031866
• Length: 1248
• Species: Drosophila melanogaster
• Sequence 2: XP_006255234.2
• Gene: Ces1c / 24346
• RGDID: 2571
• Length: 551
• Species: Rattus norvegicus
• Alignment Length: 690
• Identity: 176/690 - (25%)
• Similarity: 285/690 - (41%)
• Gaps: 184/690 - (26%)

  Fly   154 GHPEACALLVLLLLTSLWPDCCECLHGGSNTVKTKYGLLRGIVVRSSPLVEAFLGIPYASPPVGS 218
            |||.:             |...:...|   .|..||..|.|.   :.| |..|||:|:|.||:||
  Rat    20 GHPSS-------------PPVVDTTKG---KVLGKYVSLEGF---TQP-VAVFLGVPFAKPPLGS 64

  Fly   219 LRFMPPITPSTWKTVRSADRFSPVCPQNIPIPPNGPEALLEVPRARLAQLRRLLPLLKNQSEDCL 283
            |||.||.....|..|::...:.|:|.|:..:    .:.|.::    |:..:..:||  ..|||||
  Rat    65 LRFAPPEPAEPWSFVKNTTTYPPMCSQDGVV----GKLLADM----LSTGKENIPL--EFSEDCL 119

  Fly   284 YLNIYVPYETRRQRRNTDDTTGEPKTKLSTVVFIHGESYDWNSGNPYDGSELAAHGNVIVVTINF 348
            |||||.|.:..:..|            |..:|:|||........:||.|..|:||.||:||||.:
  Rat   120 YLNIYSPADLTKNSR------------LPVMVWIHGGGLIIGGASPYSGLALSAHENVVVVTIQY 172

  Fly   349 RLGIFGFLKTGGKESAQGNFGLMDLVAGLHWLKENLPAFGGDPQSITLLGYGTGAVLANILVVSP 413
            ||||:|...| |.|.::||:..:|.:|.|.|:::|:..|||:|.|:|:.|...|.|..::||:||
  Rat   173 RLGIWGLFST-GDEHSRGNWAHLDQLAALRWVQDNIANFGGNPDSVTIFGESAGGVSVSVLVLSP 236

  Fly   414 VASDLIQRTVLVSGSALSPWAIQKNPLFVKRRVAEQTGCHGDMLYDDLAPCLRTKSVAEL--LAV 476
            :|.:|..|.:..||..|:....:||...|.:.:|..:||: :.....:..|||.|:.|||  |.|
  Rat   237 LAKNLFHRAISESGVVLTTNLDKKNTQAVAQMIATLSGCN-NTSSAAMVQCLRQKTEAELLELTV 300

  Fly   477 KVDHPRFLVGFAPFVDGTVISPGANPL----GSTTLPLGSAIVSTSGIEYANFPKRDLIFCLTSV 537
            |:|:    ...:..:||.|:......:    ...|:|.           ...|.|::..:.:.::
  Rat   301 KLDN----TSMSTVIDGVVLPKTPEEILTEKSFNTVPY-----------IVGFNKQEFGWIIPTM 350

  Fly   538 ESYLDLSAQDLEFGFNETRRDRILRTFVRNNFHYHLNE--IFAVLKNEYTDWEKAIR---NPLSS 597
            ...| ||    |...||.....:||.|..|   .:::|  |.|::       ||.:|   :|...
  Rat   351 MGNL-LS----EGRMNEKMASSLLRRFSPN---LNISESVIPAII-------EKYLRGTDDPAKK 400

  Fly   598 RDATLQFLSDGHTASPLIKLGYMHSLR--GGRAYFLHFKHKT--IEEEYPQRSGSVRGEDVPFWL 658
            ::..|...||.....|.:.:.  .|||  |...|...|:::.  :.::.||......|:::....
  Rat   401 KELLLDMFSDVFFGIPAVLMS--RSLRDAGAPTYMYEFQYRPSFVSDQRPQTVQGDHGDEIFSVF 463

  Fly   659 GLPMSPLFPHNYTTQERQIGRLMLRYLSNFAKTGNPNQSTAKSVLPNPNEVLETALHQQKKRSTS 723
            |   :|......:.:|..:.:|::::.:|||:.||||
  Rat   464 G---TPFLKEGASEEETNLSKLVMKFWANFARNGNPN---------------------------- 497

  Fly   724 LTHPNLSEALNLAVLYNQRRSNAMHEKRSYIRRRLRSNDAAFTQLGISSERDVGSYDGDELPFWD 788
                                                                     |:.||.|.
  Rat   498 ---------------------------------------------------------GEGLPHWP 505

  Fly   789 AYDVVNQLYVELGNKANIQSHYRGHKLSMWLNLI----PQ 824
            .|| ..:.|:::|.........:|.:::.|..|:    ||
  Rat   506 EYD-QKEGYLQIGATTQQAQKLKGEEVAFWTELLAKNPPQ 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg2	NP_001245916.1	COesterase	182..712	CDD:278561	158/544 (29%)
Ces1c	XP_006255234.2	COesterase	24..534	CDD:395084	169/674 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810