Protein Alignment Nlg2 and Ces4a

DIOPT Version :9

• Sequence 1: NP_001245916.1
• Gene: Nlg2 / 33962
• FlyBaseID: FBgn0031866
• Length: 1248
• Species: Drosophila melanogaster
• Sequence 2: NP_666325.2
• Gene: Ces4a / 234677
• MGIID: 2384581
• Length: 563
• Species: Mus musculus
• Alignment Length: 697
• Identity: 183/697 - (26%)
• Similarity: 286/697 - (41%)
• Gaps: 194/697 - (27%)

  Fly   162 LVLLLLTSLWPDCCECLHGGSNTVKTKYGLLRG--IVVRSSPLVEAFLGIPYASPPVGSLRFMPP 224
            |.|::.|:|     ..||.....:.||:|:|:|  :.|..:| ::.|||||::.||||:.||.||
Mouse    18 LCLVVQTAL-----GALHTKEPLLITKHGILQGKQVHVGDTP-IQVFLGIPFSKPPVGTRRFAPP 76

  Fly   225 ITPSTWKTVRSADRFSPVCPQNIPIPPNGPEALLEVPRARLAQLRRLLPLLKNQ---------SE 280
            ..|..|..:|.|..:.|.|.|.                    ...::|.:..|.         ||
Mouse    77 EPPLPWNGIRDATTYPPSCLQE--------------------SWGQILSMYLNTRKQYKWLHFSE 121

  Fly   281 DCLYLNIYVPYETRRQRRNTDDTTGEPKTKLSTVVFIHGESYDWNSGNPYDGSELAAHGNVIVVT 345
            ||||||:|.|..          ..|.|  .|..:|:..|.::...|.:.|:||||||.|.|::|.
Mouse   122 DCLYLNVYAPVL----------APGAP--LLPVMVWFPGGAFLAGSASTYEGSELAARGKVVLVF 174

  Fly   346 INFRLGIFGFLKTGGKESAQGNFGLMDLVAGLHWLKENLPAFGGDPQSITLLGYGTGAVLANILV 410
            :.:||||.||..||... |:||:||:|.:|.|.|::||:.||||||.|:||.|...||:..:.|:
Mouse   175 LQYRLGILGFFSTGNSH-ARGNWGLLDQIAALRWVQENIEAFGGDPDSVTLFGQSAGAMSVSGLM 238

  Fly   411 VSPVASDLIQRTVLVSGSALSPWAIQKNPLFVKRRVAEQTGC-HGDMLYDDLAPCLRTKSVAELL 474
            |||:|..|..:.:..||:|:....|..:||...:::|...|| |.....  :..|||:.|..|:.
Mouse   239 VSPLAQGLFHQAISQSGTAVLKAFITPDPLTSAKKIAHLAGCDHNSTKV--MVECLRSLSAEEVT 301

  Fly   475 AVKV--------DH--PRFLVGF-APFVDGTVISPGANPLGSTTLPLGSAIVSTSGIEYANFPKR 528
            .|..        .|  |:.:|.| :|.|||.|..  .:|:...|......:....|:..|.| :.
Mouse   302 LVSKRMSFFQANSHKDPKEIVWFLSPVVDGVVFP--EDPVVLLTRGQVKPVPYLLGVNNAEF-EW 363

  Fly   529 DLIFCLTSVESYLDLSAQDLEFGFNETRRDRILRTFVRNNFHYHLN---EIFAVLKNEYT----- 585
            :|.|.:.     :.|:.:.:    |:|..::||.     :|:..||   |...|:..||.
Mouse   364 NLPFLMK-----IQLNQRMM----NQTNINKILW-----SFNVLLNITKEQVPVVAREYLNDAIS 414

  Fly   586 --DWEKAIRNPLSSRDATLQFLSDGHTASPLIKLGYMHSLRGGRAYFLHFKHKT----IEEEYPQ 644
              || |..||.|      :..:.|.......::....|...|...|...|||..    |.:.|
Mouse   415 NHDW-KMFRNRL------IDLIGDATFVYATLQAARYHRDAGSPVYLYEFKHHASSGIIIKPY-- 470

  Fly   645 RSGSVRGEDVPFWLGLPMSPLFPHNYTTQERQIGRLMLRYLSNFAKTGNPNQSTAKSVLPNPNEV 709
             :|:..|:::.:..|   ||....:...:|::....|::|.:|||.|||||
Mouse   471 -NGADHGDELSYLFG---SPFSKGSSAGEEKEFSLQMMKYWANFAHTGNPN-------------- 517

  Fly   710 LETALHQQKKRSTSLTHPNLSEALNLAVLYNQRRSNAMHEKRSYIRRRLRSNDAAFTQLGISSER 774
                                                                             
Mouse   518 ----------------------------------------------------------------- 517

  Fly   775 DVGSYDGDELPFWDAYDVVNQLYVELGNKANIQSHYRGHKLSMWLNL 821
                  |::||:|..:| .::.|::|.....:....:..|::.|..|
Mouse   518 ------GEKLPYWPRFD-KDEKYLQLDFDTRVGVKLKEKKMAFWSQL 557

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg2	NP_001245916.1	COesterase	182..712	CDD:278561	167/566 (30%)
Ces4a	NP_666325.2	COesterase	30..554	CDD:278561	176/675 (26%)
		Aes	<128..>272	CDD:223730	61/156 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810