Protein Alignment Nlg2 and Ces2e

DIOPT Version :9

• Sequence 1: NP_001245916.1
• Gene: Nlg2 / 33962
• FlyBaseID: FBgn0031866
• Length: 1248
• Species: Drosophila melanogaster
• Sequence 2: NP_001157228.1
• Gene: Ces2e / 234673
• MGIID: 2443170
• Length: 559
• Species: Mus musculus
• Alignment Length: 715
• Identity: 176/715 - (24%)
• Similarity: 273/715 - (38%)
• Gaps: 232/715 - (32%)

  Fly   158 ACALLVLLLLTSLWPDCCECLH-----GGSNTVKTKYGLLRGIVVR---SSPLVEAFLGIPYASP 214
            ||.:|:|:            ||     ..|....|..|.:||.:|.   :...|..|||||:|.|
Mouse    14 ACGVLLLV------------LHVQGQDSASPIRNTHTGQVRGSLVHVKDTDIAVHTFLGIPFAKP 66

  Fly   215 PVGSLRFMPPITPSTWKTVRSADRFSPVCPQNIPIPPNGPEALLEVPRARLAQLRRLLPLLKNQS 279
            |||.|||.||..|..|..||.......:|.||..:  .|.|        .|..:..:||.: :.|
Mouse    67 PVGPLRFAPPEAPEPWSGVRDGTSHPNMCLQNDNL--MGSE--------DLKMMNLILPPI-SMS 120

  Fly   280 EDCLYLNIYVPYETRRQRRNTDDTTGEPKTKLSTVVFIHGESYDWNSGNPYDGSELAAHGNVIVV 344
            |||||||||||.....            .:.|..:|:|||.:......:.||||.|||..:|:||
Mouse   121 EDCLYLNIYVPAHAHE------------GSNLPVMVWIHGGALTVGMASMYDGSMLAATEDVVVV 173

  Fly   345 TINFRLGIFGFLKTGGKESAQGNFGLMDLVAGLHWLKENLPAFGGDPQSITLLGYGTGAVLANIL 409
            .|.:|||:.||..| |.:.|:||:|.:|.||.|.|:::|:..|||:|..:|:.|...|....:..
Mouse   174 AIQYRLGVLGFFST-GDQHAKGNWGYLDQVAALRWVQQNIVHFGGNPDRVTIFGESAGGTSVSSH 237

  Fly   410 VVSPVASDLIQRTVLVSGSALSPWAIQKNPLFVKRRVAEQTGCHGDMLYDDLAPCLRTKSVAELL 474
            ||||::..|....::.||.|:.|..|..:...|.|.||..:|| ..:..:.|..|||.|:.||:|
Mouse   238 VVSPMSQGLFHGAIMESGVAVLPDLISSSSEMVHRIVANLSGC-AAVNSETLMCCLRGKNEAEML 301

  Fly   475 AVK---------VD------HPRFLVG---FAP-------------FVDGTVISPG--ANPLGST 506
            |:.         ||      ||:.|:.   |.|             ::..|::.|.  ...:...
Mouse   302 AINKVFKIIPGVVDGEFLPKHPQELMASKDFHPVPSIIGINNDEYGWILPTIMDPAQKIEEITRK 366

  Fly   507 TLPLGSAIVSTSGIEYANFPK-RDLIFCLTSVESYLDLSAQD---LEFGFNETRRDRILRTFVRN 567
            |||   |::.::.::....|: .||:     :|.|:. ..:|   |:..|.|.:.|
Mouse   367 TLP---AVLKSTALKMMLPPECGDLL-----MEEYMG-DTEDPETLQAQFREMKGD--------- 413

  Fly   568 NFHYHLNEIFAVLKNEYTDWEKAIRNPLSSRDATLQFLSDGHTASPLIKLGYMHSLRGGRAYFLH 632
                   .:|.:                    ..||......:.:|:              ||..
Mouse   414 -------FMFVI--------------------PALQVAHFQRSHAPV--------------YFYE 437

  Fly   633 FKHKT--IEEEYPQRSGSVRGEDVPFWLGLPMSPL-FPHNYTTQERQIGRLMLRYLSNFAKTGNP 694
            |:|:.  .::..|....:..|:::....|.....: .|  ||.:|.|:.|.:::|.:|||:.|||
Mouse   438 FQHRPSFFKDFRPPYVKADHGDEIFLVFGYQFGNIKLP--YTEEEEQLSRRIMKYWANFARHGNP 500

  Fly   695 NQSTAKSVLPNPNEVLETALHQQKKRSTSLTHPNLSEALNLAVLYNQRRSNAMHEKRSYIRRRLR 759
            |
Mouse   501 N---------------------------------------------------------------- 501

  Fly   760 SNDAAFTQLGISSERDVGSYDGDELPFWDAYDVVNQLYVELGNKANIQSHYRGHKLSMWLNLIPQ 824
                                 .:.||:|...|...| |::|..:.::....:..:|..|...:||
Mouse   502 ---------------------SEGLPYWPVMDHDEQ-YLQLDIQPSVGRALKARRLQFWTKTLPQ 544

  Fly   825  824
            Mouse   545  544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg2	NP_001245916.1	COesterase	182..712	CDD:278561	159/572 (28%)
Ces2e	NP_001157228.1	COesterase	30..538	CDD:278561	167/679 (25%)
		Aes	<128..>231	CDD:223730	43/115 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810