Protein Alignment Nlg2 and Ces1f

DIOPT Version :10

• Sequence 1: NP_523496.1
• Gene: Nlg2 / 33962
• FlyBaseID: FBgn0031866
• Length: 1248
• Species: Drosophila melanogaster
• Sequence 2: NP_659179.1
• Gene: Ces1f / 234564
• MGIID: 2142687
• Length: 561
• Species: Mus musculus
• Alignment Length: 579
• Identity: 161/579 - (27%)
• Similarity: 254/579 - (43%)
• Gaps: 118/579 - (20%)

  Fly   162 LVLLLLTSLWPDCCECLHGGS-NTVKTKYGLLRGIVVR----SSPLVEAFLGIPYASPPVGSLRF 221
            |..|.|.|| ..|..|.:..| ..|.|.:|.:.|..|.    |.| |..|||||:|.||:|||||
Mouse     3 LSTLFLVSL-ATCVICGNPSSPPVVDTAHGKVLGKHVNVEGFSQP-VAVFLGIPFAKPPLGSLRF 65

  Fly   222 MPPITPSTWKTVRSADRFSPVCPQNIPIPPNGPEALLEVPRARLAQLRRLLPLLKNQ-----SED 281
            .||.....|.:|::|..:.|:|.|:               .||...:..|:...|.:     |||
Mouse    66 APPQPAEPWSSVKNATTYPPMCSQD---------------AARGQAVNDLITNRKEKIHLEFSED 115

  Fly   282 CLYLNIYVPYETRRQRRNTDDTTGEPKTKLSTVVFIHGESYDWNSGNPYDGSELAAHGNVIVVTI 346
            |||||||.|.:..:..|            |..:|:|||........:.:||..|:|:.||:||.|
Mouse   116 CLYLNIYTPADFSKNSR------------LPVMVWIHGGGLKLGGASSFDGRALSAYENVVVVAI 168

  Fly   347 NFRLGIFGFLKTGGKESAQGNFGLMDLVAGLHWLKENLPAFGGDPQSITLLGYGTGAVLANILVV 411
            .:||.|:||..| |.|.::||:|.:|.||.|||:::|:..|||||.|:|:.|...|....:||::
Mouse   169 QYRLSIWGFFST-GDEHSRGNWGHLDQVAALHWVQDNIANFGGDPGSVTIFGESAGGYSVSILIL 232

  Fly   412 SPVASDLIQRTVLVSGSALSPWAIQKNPLFVKRRVAEQTGC---------HGDMLYDDLAPCLRT 467
            ||::.:|..|.:..||.|..|....|:...:..::|...||         |          |:|.
Mouse   233 SPLSKNLFHRAISESGVAFIPGMFTKDVRPITEQIAVTAGCKTTTSAVIVH----------CMRQ 287

  Fly   468 KSVAELLAV--------------KVDHPRFLVGFAPFVDGTVISPGANPL----GSTTLPLGSAI 514
            |:..|||.:              ..:..:|:..   .:||.|:......:    ...|:|.   |
Mouse   288 KTEEELLEIMHKLNLYKLSLQGDTKNSDQFVTS---VLDGVVLPKDPKEILAEKNFNTVPY---I 346

  Fly   515 VSTSGIEYANFPKRDLIFCLTSVESYLDLSAQDLEFGFNETRRDRILRTFVRNNFHYHLNEIFAV 579
            |   ||.     |::..:.|.::..:|....:     .::.:...:|..|.  :......:|..|
Mouse   347 V---GIN-----KQECGWLLPTMTGFLPADVK-----LDKKKAIALLEQFA--SMTGIPEDIIPV 396

  Fly   580 LKNEYTDWEKAIRNPLSSRDATLQFLSDGHTASPLIKLGYMHSLRGGRAYFLHFKHKTIEEEY-- 642
            ...:||   |...:|...|:..|..:.|.....|.:.:...|...|...|...:::      |
Mouse   397 AVEKYT---KGSDDPDQIREGVLDAMGDVAFGVPSVIVSRGHRDTGAPTYMYEYQY------YPS 452

  Fly   643 ---PQRSGSVRG---EDVPFWLGLPMSPLFPHNYTTQERQIGRLMLRYLSNFAKTGNPN 695
               |||..:|.|   :||....|   :|:.....:.:|..:.::::::.:|||:.||||
Mouse   453 FSSPQRPKNVVGDHADDVYSVFG---APILREGASEEEINLSKMVMKFWANFARNGNPN 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg2	NP_523496.1	COesterase	182..729	CDD:395084	154/559 (28%)
Ces1f	NP_659179.1	COesterase	22..545	CDD:395084	154/559 (28%)
		Prevents secretion from ER. /evidence=ECO:0000255|PROSITE-ProRule:PRU10138	558..561