Protein Alignment Nlg2 and Ces2e

DIOPT Version :9

• Sequence 1: NP_001245916.1
• Gene: Nlg2 / 33962
• FlyBaseID: FBgn0031866
• Length: 1248
• Species: Drosophila melanogaster
• Sequence 2: NP_001093947.1
• Gene: Ces2e / 192257
• RGDID: 621563
• Length: 557
• Species: Rattus norvegicus
• Alignment Length: 704
• Identity: 179/704 - (25%)
• Similarity: 276/704 - (39%)
• Gaps: 200/704 - (28%)

  Fly   153 PGHPEACALLVLLLLTSLWPDCCECLHGGSNTV----KTKYGLLRGIVVR---SSPLVEAFLGIP 210
            ||...|....:|||.         |...|.::.    .|..|.:||..|.   :...|..|||||
  Rat     7 PGWLNAVVWGLLLLF---------CQVQGQDSASPIRNTHTGQVRGSFVHVKDTKSGVHTFLGIP 62

  Fly   211 YASPPVGSLRFMPPITPSTWKTVRSADRFSPVCPQNIPIPPNGPEALLEVPRARLAQLRRLLPLL 275
            :|.||:|.|||.||..|..|..||.......:|.|||    :|    |.:...::...|.  |:
  Rat    63 FAKPPIGPLRFAPPEPPEPWSGVRDGTSHPAMCLQNI----DG----LNLENLKIKMSRS--PV- 116

  Fly   276 KNQSEDCLYLNIYVPYETRRQRRNTDDTTGEPKTKLSTVVFIHGESYDWNSGNPYDGSELAAHGN 340
             :.|||||||:||.|..|.:.            :.|..:|:|||....|...:.||||.|||..:
  Rat   117 -SMSEDCLYLSIYTPAHTHKD------------SNLPVMVWIHGGGLCWGMASTYDGSMLAAIED 168

  Fly   341 VIVVTINFRLGIFGFLKTGGKESAQGNFGLMDLVAGLHWLKENLPAFGGDPQSITLLGYGTGAVL 405
            |:||||.:||||.||..| |.|.|:||:|.:|.||.|.|:::|:..|||:|..:|:.|...|.:.
  Rat   169 VVVVTIQYRLGILGFFST-GDEHARGNWGYLDQVAALRWVQQNIVHFGGNPDRVTIFGESAGGIS 232

  Fly   406 ANILVVSPVASDLIQRTVLVSGSALSPWAIQKNPLFVKRRVAEQTGCHGDMLYDDLAPCLRTKSV 470
            .:..||||::..|....::.||.||.|..|......:...||..:||. .:..:.|..|||.||.
  Rat   233 VSSHVVSPMSQGLFHGAIMESGVALLPNLISNTSEVIYTMVANLSGCE-PVDSEALMSCLREKSE 296

  Fly   471 AELLAVKVDHPRFLVGFAPFVDGTVISPGANPLGSTTLPLGSAIVST-SGIEYANFPKRDLIFCL 534
            .|:||:                                   :.||.| ||:....|..|..:..|
  Rat   297 EEMLAI-----------------------------------NNIVRTISGVVDGKFLPRHPLELL 326

  Fly   535 TSVE-----SYLDLSAQDLEFGFNETRRDRILRTFVRNNFHYHLNEIFAVLKN---------EYT 585
            .||:     |.:.:::.:..:.......|..::...|....       |||||         |.:
  Rat   327 ASVDFHPVPSIIGINSDEYGWIIPMLHPDSTMKEINRETMR-------AVLKNTAVQMMLPPECS 384

  Fly   586 D--WEKAIRNPLSSRDATLQF---LSDGHTASPLIKLGYMHSLRGGRAYFLHFKHKT--IEEEYP 643
            |  .|:.:.:...|:...:||   :.|.....|.:::.:..... ...||..|:|::  :::..|
  Rat   385 DLLMEEYMGDTEDSKTLQIQFNEMMGDFIFVIPALQVAHFQRSH-APVYFYEFQHQSNFLKDIRP 448

  Fly   644 QRSGSVRGEDVPFWLGLPMSPLF---PHNYTTQERQIGRLMLRYLSNFAKTGNPNQSTAKSVLPN 705
            ....:..|:::|:.:|.    ||   ...:|.:|:.:.|.|::|.:|||:.||||
  Rat   449 PHVKADHGDELPYVIGY----LFWDMKFVFTEEEKLLSRKMIKYWANFARHGNPN---------- 499

  Fly   706 PNEVLETALHQQKKRSTSLTHPNLSEALNLAVLYNQRRSNAMHEKRSYIRRRLRSNDAAFTQLGI 770
                                                                             
  Rat   500 ----------------------------------------------------------------- 499

  Fly   771 SSERDVGSYDGDELPFWDAYDVVNQLYVELGNKANIQSHYRGHKLSMWLNLIPQ 824
                      .:.||:|.|.|...| |::|..:..:....:..:|..|...:||
  Rat   500 ----------SEGLPYWPALDHDEQ-YLQLDIQPVVGRALKARRLKFWTKTLPQ 542

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg2	NP_001245916.1	COesterase	182..712	CDD:278561	159/561 (28%)
Ces2e	NP_001093947.1	COesterase	30..536	CDD:278561	168/664 (25%)
		Aes	<127..>230	CDD:223730	47/115 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810