Protein Alignment Nlg2 and cest-28

DIOPT Version :9

• Sequence 1: NP_001245916.1
• Gene: Nlg2 / 33962
• FlyBaseID: FBgn0031866
• Length: 1248
• Species: Drosophila melanogaster
• Sequence 2: NP_504691.2
• Gene: cest-28 / 187305
• WormBaseID: WBGene00019654
• Length: 548
• Species: Caenorhabditis elegans
• Alignment Length: 619
• Identity: 151/619 - (24%)
• Similarity: 254/619 - (41%)
• Gaps: 142/619 - (22%)

  Fly   182 SNTVKTKYGLLRGIVVR-SSPLVEAFLGIPYASPPVGSLRFMPPITPSTWKTVRSADRFSPVCPQ 245
            |..:....|.::|.|.| ....|:.:||||:|.|.|   ||..|....||:.||...::.|.|||
 Worm    14 SEKLNATCGPIQGNVYRIGDKTVDGYLGIPFAKPLV---RFKKPEPAGTWEEVRDCTKYGPRCPQ 75

  Fly   246 NIPIPPNGPEALL----EVPRARLAQLRRLLPLLKNQSEDCLYLNIYVPYETRRQRRNTDDTTGE 306
            :.|.    .||:.    ::|                ...:||.||::         ....|:...
 Worm    76 SGPF----AEAINFQKDDIP----------------DEANCLTLNVF---------SKISDSKNF 111

  Fly   307 PKTKLSTVVFIHGESYDWNSGNPYDGSELAAH---GNVIVVTINFRLGIFGFLKTGGKESAQGNF 368
            .||: ..:|:|||..|:.::...|....:|..   .:|:|||:|:|:||.||..| |.....|||
 Worm   112 NKTR-PVMVYIHGGGYECSASRDYCDYSVAGTLPLKDVVVVTLNYRVGILGFFTT-GDTVCPGNF 174

  Fly   369 GLMDLVAGLHWLKENLPAFGGDPQSITLLGYGTGAVLANILVVSPVASDLIQRTVLVSGSALSPW 433
            .|.||..||:|:::::.:|||||.:||:.|...||...::|.:||.:.||..|.:::||.||..:
 Worm   175 ALWDLTLGLNWIQKHIESFGGDPGNITIFGQSAGAACVDLLALSPHSRDLFNRVIVMSGGALCEY 239

  Fly   434 AI-----QKNPLFVKRRVAEQTGCHGDMLYDDLAPCLRTKSVAELLAVKVDHPRFLVGFAPFVDG 493
            |:     |....:...|.....|.:...|::    .:::|.:.|:..:.        ||
 Worm   240 AVRTANSQAKVCYEFARHLGYDGTNSQTLFN----WMKSKPLEEIEKMN--------GF------ 286

  Fly   494 TVISPGANPLGSTTLPLGSAIVSTSGIEYANFPKRDLIFCLTSVESYLDLSAQDLEFGFNETRRD 558
                         .:|....:..|..::...|||       :..|..:....:|:..||.|  .:
 Worm   287 -------------QVPASGILAWTPNLDDDFFPK-------SLDELRIGAPKKDIMMGFAE--HE 329

  Fly   559 RILRTFVRNN-------FHYHLNEIFAVLKNEYTDWEKAIRNPL--------------SSRDATL 602
            .:...|:..:       ...::||.:   |.:..|..:|.||.:              |:::..:
 Worm   330 GLFFEFLIKDPTPPLEALKLYVNEYY---KKDTGDHFEATRNKIIEFYSRNVEDTDEKSTKERLI 391

  Fly   603 QFLSDGHTASPLIKLGYM----HSLRGGRAYFLH---------FKHKTIEEEYPQRSGSVRGEDV 654
            .|:.|.     |...|..    :.|:.|...:|:         |.:   :||:..........|:
 Worm   392 DFVGDA-----LFTAGVFDNAKNCLKHGNNVWLYIFDYCNPSGFGN---QEEFMTFVAPTHCTDL 448

  Fly   655 PFWLGLPM-SPLFPHNYTTQERQIGRLMLRYLSNFAKTGNPNQSTA----KSVLPNPNEVLETAL 714
            .:.||..: |...|   |.:|.::...|....|||||.||||:..:    |..|.||....:.:.
 Worm   449 RYVLGEGLYSDFQP---TEEEHKMIEKMTTIYSNFAKYGNPNEHGSSEWEKFTLDNPRRHFQISY 510

  Fly   715 HQQKKRSTSLTHPNLSEALNLAVLYNQRRSNAMH 748
            .:.|.|:.  .||:..:.|.|....||...|.::
 Worm   511 PRGKMRND--YHPDRMKFLELIRAKNQNLENVVY 542

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg2	NP_001245916.1	COesterase	182..712	CDD:278561	142/581 (24%)
cest-28	NP_504691.2	COesterase	17..516	CDD:278561	142/586 (24%)
		Aes	<112..>222	CDD:223730	43/111 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810