Protein Alignment Nlg2 and cest-31

DIOPT Version :9

• Sequence 1: NP_001245916.1
• Gene: Nlg2 / 33962
• FlyBaseID: FBgn0031866
• Length: 1248
• Species: Drosophila melanogaster
• Sequence 2: NP_504692.3
• Gene: cest-31 / 187304
• WormBaseID: WBGene00019653
• Length: 541
• Species: Caenorhabditis elegans
• Alignment Length: 554
• Identity: 150/554 - (27%)
• Similarity: 230/554 - (41%)
• Gaps: 124/554 - (22%)

  Fly   183 NTVKTKYGLLRGIVVR-SSPLVEAFLGIPYASPPVGSLRFMPPITPSTWKTVRSADRFSPVCP-- 244
            |.:.:..|.::|.:.| .:..|..:||||||.||:|.|||..|::...|...|...::.|.||
 Worm    15 NVLNSTCGPVQGNLYRHGNEEVHGYLGIPYAQPPIGILRFKKPVSADVWTETRDCTKYGPRCPPS 79

  Fly   245 ----QNIPIPPNGPEALLEVPRARLAQLRRLLPLLKNQSEDCLYLNIYVPYETRRQRRNTDDTTG 305
                :|:.:|..      ::|                ...:||.||::.|....:|
 Worm    80 GMLYENLQLPNT------DIP----------------DEANCLSLNVFCPQWEIKQ--------- 113

  Fly   306 EPKTKLSTVVFIHGESYDWNSGNPYDGSELAAH---GNVIVVTINFRLGIFGFLKTGGKESAQGN 367
              ..|...::||||..::.::...|....|:..   .:|||||:|:|:|..|||.| |.:|.:||
 Worm   114 --SAKHPVMIFIHGGGFELSASKDYCDYSLSGTLPLKDVIVVTVNYRVGALGFLTT-GDDSCRGN 175

  Fly   368 FGLMDLVAGLHWLKENLPAFGGDPQSITLLGYGTGAVLANILVVSPVASDLIQRTVLVSGSALSP 432
            |||.||...|.|:..::.:|||||:::||.|...|||.|::|.:||.:.||..:.:::||||..|
 Worm   176 FGLWDLTLALKWVSTHISSFGGDPKNVTLFGQSAGAVCADLLNLSPYSRDLFHKLIIMSGSAHVP 240

  Fly   433 WAI--QKNPLFVKRRVAEQTGCHGDMLYDDLAPCLRTKSVAELL-------AVKVDHPRFLVGFA 488
            :||  ::|...|....|...|..|.. ..:|........:.:||       .|.:|     :.||
 Worm   241 FAIRTEENQALVCMEYARSRGFSGSG-SAELLEFFENLPIEKLLEKTGLKHTVSID-----LSFA 299

  Fly   489 PFVDGTVISPGANPLGSTT--LPLGSAIVSTSGIEYANFPKRDLIFCLTSVESYLDLSAQDLEFG 551
            |.:||.........|...|  .|:...::...|:..| |...|...|..:.:..::
 Worm   300 PNLDGDFFPKPLEELRRETRKKPVIVGMMEDEGLITA-FADGDFTTCEENFKRRVE--------- 354

  Fly   552 FNETRRDRILRTFVRNNFHYHLNEIFAVLKNEYTDW--EKAIRNPLSSRDATLQFLSD--GHTAS 612
             :|.|.|     .|.|..:...|     :.|.||::  |...|.           |.|  ||:
 Worm   355 -SEYRGD-----VVENPENVQKN-----IMNFYTNYCDESEERK-----------LVDYIGHS-- 395

  Fly   613 PLIKLGYMHSLR-----GGRAYFLHFKHKTIEEEYPQRSGSVRGEDVPFWLGLPMSPL------- 665
             :...|.:.|..     |...||..|....     |...|.| |..|||......|.|
 Worm   396 -VYNAGVLLSAESLARAGNCVYFYVFDFWN-----PDGFGPV-GSIVPFKGAAHCSELRYIIGEG 453

  Fly   666 FPHNYTTQERQIGRLMLRYL----SNFAKTGNPN 695
            ....:...|:.:  .|:.|:    :||||.||||
 Worm   454 VYSKFDANEKDL--KMMEYMTTMFTNFAKYGNPN 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg2	NP_001245916.1	COesterase	182..712	CDD:278561	150/554 (27%)
cest-31	NP_504692.3	COesterase	16..522	CDD:278561	149/553 (27%)
		Aes	<112..>211	CDD:223730	39/110 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810