Protein Alignment Nlg2 and cest-8

DIOPT Version :9

• Sequence 1: NP_001245916.1
• Gene: Nlg2 / 33962
• FlyBaseID: FBgn0031866
• Length: 1248
• Species: Drosophila melanogaster
• Sequence 2: NP_001359583.1
• Gene: cest-8 / 182818
• WormBaseID: WBGene00007691
• Length: 605
• Species: Caenorhabditis elegans
• Alignment Length: 748
• Identity: 153/748 - (20%)
• Similarity: 250/748 - (33%)
• Gaps: 255/748 - (34%)

  Fly   161 LLVLLLLTSLWPDCCECLHGGSNTVK---TKYGLLRGIVVRSSPLVE--AFLGIPYASPPVGSLR 220
            |:.:|||.||..:        ..|:|   |.||.|||:...|.....  .|..:|:|.||:|:||
 Worm     2 LVSILLLCSLLYE--------FQTLKIINTSYGKLRGMAEWSDDANHKFTFKSVPFAKPPIGNLR 58

  Fly   221 FMPPITPSTWKTVRSADRFSPVCPQNIPIPPNGPEALLEVPRARLAQLRRLLPLLKNQS---EDC 282
            |.||.....|..:..|..:|..|..|                          ..|..||   |||
 Worm    59 FAPPQKLDHWDGILDASVYSAACMSN--------------------------STLTTQSYVNEDC 97

  Fly   283 LYLNIYVPYETRRQRRNTDDTTGEP--KTKLSTVVFIHGESYDWNSGNPYDGS---ELAAHGNVI 342
            ||:||:               |.|.  |:|.|.:|:.||.:|:..|...:...   :...|.:||
 Worm    98 LYINIF---------------TSEKCLKSKCSVIVYFHGGAYNTESATMFSDRFILDRYVHEDVI 147

  Fly   343 VVTINFRLGIFGFLKTGGKESAQGNFGLMDLVAGLHWLKENLPAFGGDPQSITLLGYGTGAVLAN 407
            .|....|||:||.|..|.......|..:.|.:..|.::...:..|||||:.:|::|:.:|..|..
 Worm   148 FVIPAVRLGVFGQLYFGPNAYLTENLFMFDAILALDFVHNEISNFGGDPEKVTIMGHSSGGTLVE 212

  Fly   408 ILVVSPVAS---DLIQRTVLVSGSALSPWAIQKNPLFVKR--RVAEQTGCHGDMLYD-------D 460
            .|..|.:..   .|.|:.:::|.:.:..:    :.|.:..  .:.|:.||......:       :
 Worm   213 ALGFSSMVDPELKLFQQMIMLSSTGMFGF----DDLVIDNSFTIVEKLGCFNGTKEERNTVNVAE 273

  Fly   461 LAPCLRTKSVAELLAVK-----VDHP--RFLVGFAPFVDGTVISPGANPLGSTTLPLGSAIVSTS 518
            ...|:|.....|:|.|:     :|..  ::|:..|||:   :::.....|...|.| .:||..|:
 Worm   274 TLDCMRHIDGYEILRVQQKMELMDQLSFKYLLRGAPFM---LLNGNIADLKKNTSP-RNAIFGTT 334

  Fly   519 GIEYANFPKRDLIFCLTSVESYLDLSAQDLEFGFNETRRDRILRTFVRNNFHYHLNEIFAVLKNE 583
            ..|:         |.:|....|:.::..|.|   |...        |..|:...|      :||.
 Worm   335 EHEF---------FDVTEKYLYITVTFLDYE---NPVA--------VARNYDGRL------MKNM 373

  Fly   584 YTDWEKAIRNPLSSRDATLQFLSDGHTASPLIKLG---YMHSLRGGRAYFLHFKHKTIEEEYPQR 645
            .|         :.:.|:...|:|....|:.:...|   ::...|                    :
 Worm   374 ET---------MITGDSAAIFVSTATCAAAMANAGADVFLFETR--------------------Q 409

  Fly   646 SGSVRGEDVPFWLGLPMSPLFPHNYTTQERQIGRLMLRYLSNFAKTGNPNQSTAKSVLPNPNEVL 710
            |.||...|:.:::|...:    ||.|.....:.....:.|:||.|.|.|:
 Worm   410 SYSVHVSDMQYFIGNHCA----HNRTIDIDILDSFYSKLLTNFTKHGKPS--------------- 455

  Fly   711 ETALHQQKKRSTSLTHPNLSEALNLAVLYNQRRSNAMHEKRSYIRRRLRSNDAAFTQLGISSERD 775
                                                                             
 Worm   456 ----------------------------------------------------------------- 455

  Fly   776 VGSYDGDELPFWDAYDVVNQLYVELGNKANIQS------HYRGHKLSMWLNLIPQLHRHFNINDQ 834
                     |.||..|.....|:||...:..:|      .|....:|.|:..:.:    |:.|..
 Worm   456 ---------PGWDPVDPGRMNYLELKVDSKARSGPVMLEGYHAKDVSFWVGEMTE----FDQNVS 507

  Fly   835 SMRHH-----QFQDDMNNRDLYEGVVRPQLQTK 862
            .|||.     :.||..:.|..:..:|......|
 Worm   508 KMRHSEGLPPERQDTKSQRQYWNFIVYQNFDAK 540

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg2	NP_001245916.1	COesterase	182..712	CDD:278561	126/564 (22%)
cest-8	NP_001359583.1	Abhydrolase	19..495	CDD:389770	135/672 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810