Protein Alignment Nlg2 and cest-30

DIOPT Version :10

• Sequence 1: NP_523496.1
• Gene: Nlg2 / 33962
• FlyBaseID: FBgn0031866
• Length: 1248
• Species: Drosophila melanogaster
• Sequence 2: NP_504407.1
• Gene: cest-30 / 181871
• WormBaseID: WBGene00015071
• Length: 578
• Species: Caenorhabditis elegans
• Alignment Length: 591
• Identity: 151/591 - (25%)
• Similarity: 245/591 - (41%)
• Gaps: 118/591 - (19%)

  Fly   159 CALLVLL---LLTSLWPDCCECLHGGSNTVKTKYGLLRGIVVR---SSPLVEAFLGIPYASPPVG 217
            |.||.::   .|.:|.|:      ..|..:....|.:||.:.:   .:.:|:.:||||:|..|||
 Worm    11 CLLLSIVEGGFLVNLTPE------KNSQILNAPCGPIRGNIYKHKNGTKIVDGYLGIPFAKAPVG 69

  Fly   218 SLRFMPPITPSTWKTVRSADRFSPVCPQNIPIPPNGPEALLEVPRARLAQLRRLLPLLKNQSEDC 282
            :|:|..|:....|...|....:.|.|||.     ....||.....|..|:            |:|
 Worm    70 ALKFKKPVAAEKWTEPRDCYEYGPGCPQT-----GRFAALTAKSTAAFAE------------ENC 117

  Fly   283 LYLNIYVPYETRRQRRNTDDTTGEPKTKLSTVVFIHGESYDWNSGNPYDGSELAAH---GNVIVV 344
            |.||::.|    |.:      ..|....|..:|:|:|..|:....:..|...|...   .:||||
 Worm   118 LTLNVFAP----RWK------LAEFPKGLPVLVYIYGGGYEIGFTSYMDDYSLTGTLPLKDVIVV 172

  Fly   345 TINFRLGIFGFLKTGGKESAQGNFGLMDLVAGLHWLKENLPAFGGDPQSITLLGYGTGAVLANIL 409
            |:|:|||..||| |.....|.||:||.|....|.|:::|:.:|||:|:|:||.|...||...:.|
 Worm   173 TMNYRLGPLGFL-TIADGIANGNYGLWDQTLALQWVQDNIASFGGNPESVTLSGTSAGATSTDFL 236

  Fly   410 VVSPVASDLIQRTVLVSGSALSPWAIQKNPLFVKRRVAEQ-------TGCHGDMLYDDLAPCLRT 467
            .:||.::.|.||::.:||:|...:||:  |..|:..|.::       ||.....|:|
 Worm   237 SLSPHSNQLFQRSISMSGTAFCNFAIR--PKDVEVGVCKEFAQFQGYTGTDSQSLFD-------- 291

  Fly   468 KSVAELLAVKVDHPRFLVGFAPFVDGTV-ISPGANPLGSTTLPLGSAIVSTSGIEYANFPKRDLI 531
                ..:|..|...:.:.||.....|.| ..|..:         |........|.....||:|.:
 Worm   292 ----WYMAQNVSKFKEVAGFQSTAAGAVPFIPNFD---------GDFFPKPFDILRREAPKKDAL 343

  Fly   532 FCLTSVESYLDLSAQDLEFG---FNETRRDRILRTFVRNNFHYHLNEIFAV-LKNEYTDWEKA-- 590
            ..:.::||          .|   ||.      |.....|||...:||.:.. :.:.|.|.:|.
 Worm   344 ITVVTMES----------VGMIIFNP------LFANAYNNFEGFINETYGPDVTDYYADVKKKLT 392

  Fly   591 ---IRNPLSSRDATLQFLSDGHTASPLIKLGYMHSLR-----GGRAY---FLHFKHKT---IEEE 641
               :::..:|..||:......:.:..:...|.:.:::     |.:.|   |.:|...|   :|..
 Worm   393 GFYLKDVNASDKATVNRRVVDYVSDSVFNSGTLDAVKSYVKYGNKVYLGSFNYFNDATKDMVELM 457

  Fly   642 YPQRSGSVRGEDVPFWLGLPMSPLFPHNYTTQERQIGRLMLRYLSNFAKTGNPN-QSTAKSVLP- 704
            .|.:..| ...|..::.|..:...|  ..|.:|.::..:....::||.|.|:|| :|..|...|
 Worm   458 QPFKEAS-HSSDFKYYFGSGVMANF--TPTDEEMEVMDMSGTLMANFVKYGDPNGKSGTKPWKPY 519

  Fly   705 ---NPN 707
               .||
 Worm   520 TILKPN 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg2	NP_523496.1	COesterase	182..729	CDD:395084	145/565 (26%)
cest-30	NP_504407.1	COesterase	30..547	CDD:395084	145/566 (26%)