Protein Alignment Nlg2 and cest-9.1

DIOPT Version :10

• Sequence 1: NP_523496.1
• Gene: Nlg2 / 33962
• FlyBaseID: FBgn0031866
• Length: 1248
• Species: Drosophila melanogaster
• Sequence 2: NP_001359584.1
• Gene: cest-9.1 / 181383
• WormBaseID: WBGene00007692
• Length: 614
• Species: Caenorhabditis elegans
• Alignment Length: 562
• Identity: 122/562 - (21%)
• Similarity: 212/562 - (37%)
• Gaps: 167/562 - (29%)

  Fly   185 VKTKYGLLRGIVVRSSPLVEAFL--GIPYASPPVGSLRFMPPITPSTWKTVRSADRFSPVCPQNI 247
            ::|.||.||||.|.|:.....::  .:|:|.||||:|||..|..|.:|..:..|.::||.|..|
 Worm    21 IQTSYGKLRGITVWSNDKNHRYMFKSVPFAKPPVGNLRFAKPQNPESWSGILDASKYSPACMSN- 84

  Fly   248 PIPPNGPEALLEVPRARLAQLRRLLPLLKNQSEDCLYLNIYVPYETRRQRRNTDDTTGEP--KTK 310
                   .:....|:             |:.||||||:||:               |.|.  .:|
 Worm    85 -------SSSTSTPQ-------------KHYSEDCLYINIF---------------TSEKCLNSK 114

  Fly   311 LSTVVFIHGESYDWNSGNPYDGS---ELAAHGNVIVVTINFRLGIFGFLKTGGKESAQGNFGLMD 372
            ...:|:.||.:|:.:|...::.:   :..|..:|:.|....|||:||.|..|..:....|..|.|
 Worm   115 CPVIVYFHGGAYNLDSAIMFNDTFILDRYAAEDVVFVIPAVRLGVFGQLYFGPSDLLSENLFLYD 179

  Fly   373 LVAGLHWLKENLPAFGGDPQSITLLGYGTGAVLANILVVSPVAS---DLIQRTVLVSGSALSPW- 433
            .|..|.::...:..||||.:.:|.:|:.:|..:.:.|..|.:..   .|.|:.:::|.:.:..:
 Worm   180 AVQALSFVHSEINYFGGDSKRVTAMGHSSGGTIVDALGFSKLIDPGVKLFQQMIVLSATGMFGFY 244

  Fly   434 -AIQKNPLFVKRRVAEQTGCHGDMLYD-------DLAPCLRTKSVAELLAV-----KVDHPRF-- 483
             .:..|..    .:.|:.||:.....|       ::..|:|.....|:|.:     :||...|
 Worm   245 DMVVDNSF----AIVEKFGCYNGTKDDRPNANIAEMLDCMRQIDGREMLLMQRHMEEVDDRDFRS 305

  Fly   484 LVGFAPFVD--GTVISPGANPLGSTTLPLGSAIVSTSGIEYANFPKRDLIFCLTSVESYLDLSAQ 546
            ::..|||::  |.:.....:|                       |.|:|::..|..|
 Worm   306 VLRGAPFLESNGKIADLKKSP-----------------------PSRNLLYGTTEHE-------- 339

  Fly   547 DLEFGFNETRRDRILRTFVRNNFHY--HLNEIFAVLKN-----EYTDWEKAIRN--PLSSRDATL 602
                              .||..|.  :::.||....|     .|.| |:.:.|  .:.:.||..
 Worm   340 ------------------FRNVDHMNPYISGIFLDFDNPVAVARYYD-EQLMANLETMINGDAAA 385

  Fly   603 QFLSDGHTASPLIKLG---YMHSLRGGRAYFLHFKHKTIEEEYPQRSGSVRGEDVPFWLGL---- 660
            .|:.....::.:...|   |:...|                   |:..|....|:.:::|:
 Worm   386 IFICASTFSTAMANTGADVYLFETR-------------------QKPYSFHVSDMQYFVGIHREI 431

  Fly   661 ---PMSPLFPHNYTTQERQIGRLMLRYLSNFAKTGNPNQSTA 699
               |...:....|:           :.|.||.|.|.|:...|
 Worm   432 YHRPDMDILDTFYS-----------KLLVNFTKMGVPSPEWA 462

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg2	NP_523496.1	COesterase	182..729	CDD:395084	122/562 (22%)
cest-9.1	NP_001359584.1	alpha/beta hydrolases	19..484	CDD:473884	122/562 (22%)