Protein Alignment Nlg2 and glit-1

DIOPT Version :10

• Sequence 1: NP_523496.1
• Gene: Nlg2 / 33962
• FlyBaseID: FBgn0031866
• Length: 1248
• Species: Drosophila melanogaster
• Sequence 2: NP_508807.1
• Gene: glit-1 / 180747
• WormBaseID: WBGene00018878
• Length: 730
• Species: Caenorhabditis elegans
• Alignment Length: 563
• Identity: 144/563 - (25%)
• Similarity: 232/563 - (41%)
• Gaps: 117/563 - (20%)

  Fly   179 HGGSNTVKTKYGLLRGIVVRSSPLVEAFLGIPYASPPVGSLRFMPP--ITPSTWKTVRSADRFSP 241
            |...|.:|.|..:          .|..|||:|||.||....||.||  :|....|....|..::.
 Worm    92 HFDPNPLKPKNNI----------TVFTFLGVPYAEPPTSQRRFKPPQQLTVFPGKQPYLAFNYAA 146

  Fly   242 VCPQNIPIPPNGPEALLEVPRARLAQLRRLLPLLKNQSEDCLYLNIYVPYETRRQRRNTDDTTGE 306
            .|.|::   ...|...::.|          .|.:.:  ||||||||:.|           |.:..
 Worm   147 SCAQDV---EKSPSPFVDHP----------YPFMVD--EDCLYLNIFSP-----------DISKN 185

  Fly   307 PKTKLSTVVFIHGESYDWNSGNPYDGSELAAHGNVIVVTINFRLGIFGFLKTGGKESAQGNFGLM 371
            .:|....:||.||.::...|.|.:....||:.| ::|||:|:|||.|||:..|..|:  ||:||.
 Worm   186 AQTTYPVIVFFHGGNFQTGSANEWPAHGLASRG-MVVVTVNYRLGAFGFMSMGDSET--GNYGLQ 247

  Fly   372 DLVAGLHWLKENLPAFGGDPQSITLLGYGTGAVLANILVVSPVASDLIQRTVLVSGSALS----- 431
            |....|.::|.|:..||||||::|::|:..||......:.||.:..|.:....:||:.:|
 Worm   248 DQRLALEFVKNNIVTFGGDPQAVTVVGHDAGAASIGFHMQSPYSRHLFRSAATMSGAEVSYHSYI 312

  Fly   432 -PWAIQKNPLFVKRRVAEQTGCHGDMLYDDLAPCLRTKSVAELL----AVKVDHPRFLVGFAPFV 491
             ..|:..|......|.|..|.......:|    |:.|:|..:::    .:.:::.|:|  |.|.|
 Worm   313 GKTALAFNNTMKLGRYAGCTQAVAQHRWD----CILTRSTGDIIDATRNIPIEYNRYL--FMPTV 371

  Fly   492 DGTVISPGANPLGS-TTLPLGSAIVSTSGIEYANFPKRDLIFCLTSVESYLDLSAQDLEFGFNET 555
            ||..: || |||.: ...|.|...:                  ::.|...:.::|||   |....
 Worm   372 DGKYL-PG-NPLWTLVNAPSGETSI------------------MSPVPMLIGMNAQD---GSEVV 413

  Fly   556 RRDRILRTF-------------------VRNNFHYHLNEIFAVLKNEYTDW-EKAIRNPLSSRDA 600
            ..||.|..|                   .|:|:..:.......:.::||.| ::|.  ..:.::.
 Worm   414 LEDRRLGEFSQFNDVDHEYLKSYSLEYCYRHNYSMNREATADAILSKYTFWPDRAA--AWAIKEN 476

  Fly   601 TLQFLSDGHTASPLIKLGYMHSLRGGRAYFLHFKHKTIEEEYPQR------SGSVRGEDVPFWLG 659
            .:||.:|.:..:|:....::||..|.|. |.:..:.....::|..      .|..|..|:....|
 Worm   477 FIQFATDAYYTAPMQLSSHLHSSSGSRV-FQYVNNYNFSRQHPNLLFIPDWMGVCRDCDLYLMFG 540

  Fly   660 LPMSP-------LFPHNYTTQERQIGRLMLRYLSNFAKTGNPN 695
            .|..|       |...|:|..:|...|.....:..|:...|||
 Worm   541 YPFLPDELRPIGLRGINFTDTDRNASRTFSNIIRRFSYHQNPN 583

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg2	NP_523496.1	COesterase	182..729	CDD:395084	143/560 (26%)
glit-1	NP_508807.1	alpha/beta hydrolases	98..629	CDD:473884	142/557 (25%)