Protein Alignment Nlg2 and cest-35.1

DIOPT Version :9

• Sequence 1: NP_001245916.1
• Gene: Nlg2 / 33962
• FlyBaseID: FBgn0031866
• Length: 1248
• Species: Drosophila melanogaster
• Sequence 2: NP_504400.1
• Gene: cest-35.1 / 178912
• WormBaseID: WBGene00015067
• Length: 545
• Species: Caenorhabditis elegans
• Alignment Length: 565
• Identity: 140/565 - (24%)
• Similarity: 233/565 - (41%)
• Gaps: 133/565 - (23%)

  Fly   190 GLLRG-IVVRSSPLVEAFLGIPYASPPVGSLRFMPPITPSTWKTVRSADRFSPVCPQNIPIPPNG 253
            |.:|| |......:|:.:||||:|..|:|.|||...:....|.......::.|.|||      :|
 Worm    22 GPIRGNIYEHDDKIVDGYLGIPFAKAPIGELRFKKSVEAEKWTEPLDCYKYGPGCPQ------SG 80

  Fly   254 PEALLEVPRARLAQLRRLLPLLKNQSED-CLYLNIYVPYETRRQRRNTDDTTGEPKTKLSTVVFI 317
            ....:.||:|         ..::..:|| ||.||::.|     :.::.:...|.|     .:|:.
 Worm    81 ALGAMIVPQA---------SAIREFAEDNCLTLNVFAP-----KWKSAEFPNGLP-----VIVYF 126

  Fly   318 HGESYDWNSGNPYDGSELAAH---GNVIVVTINFRLGIFGFLKTGGKESAQGNFGLMDLVAGLHW 379
            :|..::....:.:|...|...   .:||:||.|:|:|..||..| |.:.::||:||.|....|.|
 Worm   127 YGGGFEVGFSSMFDDYSLTGTLPLKDVILVTPNYRIGPLGFFAT-GDDVSRGNWGLWDQALALQW 190

  Fly   380 LKENLPAFGGDPQSITLLGYGTGAVLANILVVSPVASDLIQRTVLVSGSALSPWAIQKNPL--FV 442
            :::::.:|||||.::|:.|...|....:.|.:||.|:....:.:.:||:|..|:.|:...:  .:
 Worm   191 VQKHIKSFGGDPSNVTISGTSAGGASVDFLSLSPHANKYFHKFIPMSGAATCPFGIRSKDVEGLI 255

  Fly   443 KRRVAEQTGCHGDMLYDDLAPCLR--TKSVAELLAVKVDHPRF----LVGFAPFVDGTVISPGAN 501
            .|..|:..|..|    :|....|.  ....||:. :|.:..::    :..|.|..||.......:
 Worm   256 FREFAKHHGYAG----NDSESLLHWYQSQDAEIF-LKAEGFKYPASGMFSFVPNYDGDFFPKPFD 315

  Fly   502 PLGSTTLPLGSAIVSTS---GIEYANF------PKRDLIFCL-------------TSVESYLDLS 544
            .|.... |...||||.:   |:.:..|      |:..|...|             .:||:||:
 Worm   316 ELRKEA-PKLDAIVSVAEYEGLGFEEFYPGQKSPQEVLTAALGPEVVRNREEVVKKAVEAYLE-- 377

  Fly   545 AQDLEFGFNETRRDRILRTFVRNNFHYHLNEIFAVLKNEYTDWEKAIRNPLSSRDATLQFLSDG- 608
                  ...:...::|.:..|         |||    .:|                   :.|.|
 Worm   378 ------NIEDKSGEKIGKKLV---------EIF----GDY-------------------YFSVGV 404

  Fly   609 -HTASPLIKLG---YMHSLRGGRAYFLHFKHKT---IEEEYPQRSGSVRGEDVPFWLGLPMSPLF 666
             .|...|.|.|   |:.|       |.:|..:|   ..|..|..:.| .|.|:.:.||..:.
 Worm   405 FDTVRSLAKYGNNVYLSS-------FNYFNPETPIMFGENRPFNAAS-HGCDIRYILGDGIG--- 458

  Fly   667 PHNYTTQERQIGRLMLRYLSNFAKTGNPNQSTA-----KSVLPNP 706
              .::.::|::..:|..||:||||.||||....     |..|.||
 Worm   459 --EFSKEDRKVMDMMGTYLTNFAKYGNPNGKGVSIPWEKYSLDNP 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg2	NP_001245916.1	COesterase	182..712	CDD:278561	140/565 (25%)
cest-35.1	NP_504400.1	COesterase	14..516	CDD:278561	140/565 (25%)
		Aes	<106..>214	CDD:223730	32/118 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810