Protein Alignment Nlg2 and cest-35.2

DIOPT Version :9

• Sequence 1: NP_001245916.1
• Gene: Nlg2 / 33962
• FlyBaseID: FBgn0031866
• Length: 1248
• Species: Drosophila melanogaster
• Sequence 2: NP_504398.1
• Gene: cest-35.2 / 178910
• WormBaseID: WBGene00016863
• Length: 544
• Species: Caenorhabditis elegans
• Alignment Length: 570
• Identity: 139/570 - (24%)
• Similarity: 228/570 - (40%)
• Gaps: 144/570 - (25%)

  Fly   190 GLLRG-IVVRSSPLVEAFLGIPYASPPVGSLRFMPPITPSTWKTVRSADRFSPVCPQNIPIPPNG 253
            |.:|| :......:|..:||||:|..|:|.|||...:....|.......::.|.|||:..:   |
 Worm    22 GPIRGNVYEHGDKIVNGYLGIPFAKAPIGDLRFKKSVEAEKWTQPLDCYKYGPGCPQSAAL---G 83

  Fly   254 PEALLEVPRARLAQLRRLLPLLKNQSEDCLYLNIYVPYETRRQRRNTDDTTGEPKTKLSTVVFIH 318
            ...:.:......|:            ::||.||::.|     :.::.:...|.|     .:|:.:
 Worm    84 ALMVSQATNHDFAE------------DNCLNLNVFAP-----KWKSAEFPNGFP-----VMVYFY 126

  Fly   319 GESYDWNSGNPYDGSELAAH---GNVIVVTINFRLGIFGFLKTGGKESAQGNFGLMDLVAGLHWL 380
            |..::....:.:|...|...   .:||:||.|:|:|..||..| |.:.|:||:||.|....|.|:
 Worm   127 GGGFEVGFSSMFDDYSLTGTLPLKDVILVTPNYRIGPLGFFAT-GDDVARGNWGLWDQALALQWV 190

  Fly   381 KENLPAFGGDPQSITLLGYGTGAVLANILVVSPVASDLIQRTVLVSGSALSPWAIQKNPL--FVK 443
            ::::.:|||||.::|:.|...|....:.|.:||.|:...|:.:.:||:|..|:.|:...:  .:.
 Worm   191 QKHIKSFGGDPSNVTISGTSAGGASVDFLSLSPHANKYFQKFIPMSGAATCPFGIRSKDVEGLIF 255

  Fly   444 RRVAEQTGCHGDMLYDDLAPCLRTKSVAELLAVKVDHPRFL------------VGFAPFVDGTVI 496
            |..|...|..|:          .:||:.:....: |...||            ..|.|..||...
 Worm   256 REFANHHGYTGN----------DSKSLLQWYQSQ-DSEIFLKAEGYKCPASGMFSFVPNFDGDFF 309

  Fly   497 SPGANPLGSTTLPLGSAIVST---SGIEYANF------PKRDLIFCL-------------TSVES 539
            ....:.|......|| ||||.   .|:.:.:|      |::.|...|             .:.||
 Worm   310 PKPFDELRKEAPKLG-AIVSIGEYEGLGFEDFYAGQKTPQQMLSAALGPEVVRNREEVVKRAAES 373

  Fly   540 YLDLSAQDLEFGFNETRRDRILRTFVRNNFHYHLNEIFAVLKNEYTDWEKAIRNPLSSRDATLQF 604
            |       |:.|.|| ..:.|.:|.|         |||    .:|                   :
 Worm   374 Y-------LKNGGNE-NEENIAKTLV---------EIF----GDY-------------------Y 398

  Fly   605 LSDG--HTASPLIKLG---YMHSLRGGRAYFLHFKHKT---IEEEYPQRSGSVRGEDVPFWLGLP 661
            .|.|  .|...|:|.|   |::|       |.:|...|   ..:..|..:.: .|.|:.:..|..
 Worm   399 FSVGAFDTVRSLVKYGNTVYLYS-------FNYFNPNTPIVFGKNRPFNAAN-HGSDLRYIFGEG 455

  Fly   662 MSPLFPHNYTTQERQIGRLMLRYLSNFAKTGNPNQSTA-----KSVLPNP 706
            ..     .::.::||:..:|..|.:||||.||||....     |..|.||
 Worm   456 TG-----EFSKEDRQVMDMMGTYHTNFAKYGNPNGKGVSVPWEKYSLDNP 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg2	NP_001245916.1	COesterase	182..712	CDD:278561	139/570 (24%)
cest-35.2	NP_504398.1	COesterase	14..515	CDD:278561	139/570 (24%)
		Aes	<105..>239	CDD:223730	41/144 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810