Protein Alignment Nlg2 and ges-1

DIOPT Version :10

• Sequence 1: NP_523496.1
• Gene: Nlg2 / 33962
• FlyBaseID: FBgn0031866
• Length: 1248
• Species: Drosophila melanogaster
• Sequence 2: NP_503411.1
• Gene: ges-1 / 178633
• WormBaseID: WBGene00001578
• Length: 562
• Species: Caenorhabditis elegans
• Alignment Length: 630
• Identity: 153/630 - (24%)
• Similarity: 253/630 - (40%)
• Gaps: 121/630 - (19%)

  Fly   161 LLVLLLLTSLWPDCCECLHGGSNTVKTKYGLLRGIVVRSSPLVEAFLGIPYASPPVGSLRFMPPI 225
            |:.::|:.:.|         ....|:|.||.:.||....:   |.||.||:|.|||..|||..|:
 Worm     5 LVSVILINACW---------AGPIVETNYGKVEGIEYEGA---EVFLAIPFAKPPVDDLRFEKPV 57

  Fly   226 TPSTWKTVRSADRFSPVCPQNIPIPPNGPEALLEVPRARL-AQLRRLLPLLKNQSEDCLYLNIYV 289
            .|..|:.|..|.::...|                .|..|| ||..      ....||||.|||..
 Worm    58 APDPWEDVYPATQYRNDC----------------TPHYRLVAQFS------SYSGEDCLTLNIIK 100

  Fly   290 PYETRRQRRNTDDTTGEPKTKLSTVVFIHGESYDWNS----GNPYDGSELAAHGNVIVVTINFRL 350
            |.:..               ||..:.:|||..|:..|    |..:.....|:.| |||.|:.:||
 Worm   101 PKKAE---------------KLPVLFWIHGGGYEIGSASQHGYEFFAKRYASQG-VIVATVQYRL 149

  Fly   351 GIFGFLKTGGKESAQGNFGLMDLVAGLHWLKENLPAFGGDPQSITLLGYGTGAVLANILVVSPVA 415
            |..||...|..: .|||:||.|..|.|.::|.|:..|||||..||:.||..||...:.|.:||..
 Worm   150 GFMGFFSEGTSD-VQGNWGLFDQAAALEFVKSNIENFGGDPNQITIWGYSAGAASVSQLTMSPYT 213

  Fly   416 SDLIQRTVLVSGSALSPWAIQKNPLFVKRRVAEQTGCHGDMLYDDLAPCLRTKSVAELL-AVKV- 478
            .|...:.:::|.|:...||...|.:...:::||..||.    :.....|::.||:.|:. |::|
 Worm   214 RDSYSKAIIMSASSFVGWATGPNVVETSKQLAEILGCP----WPGAKECMKKKSLHEIFDAIEVQ 274

  Fly   479 -------DHPRFLVGFAPFVDGTVISPGANPLGSTTLPLGSAIVSTSGIEYANFPKRDLIFCLTS 536
                   |    ::.::|.:||..::.....|...: |:...::..|..|.:.|...:    :..
 Worm   275 GWTTGTID----ILRWSPVIDGDFMTKNPEELIKES-PVKPTLIGMSNKEGSYFAALN----MGR 330

  Fly   537 VESYLDLSAQDLEFGFNETRRDRILRTFVRNNFHYHLNEIFAVLKNEYTDWEKAIRNPLSSRDAT 601
            |.:...||.:|:.....|...:.|.|..:.||.:....|   .:.|:..|:......|...:|..
 Worm   331 VIADFGLSPEDMPKVDEEFISEIIGRKLLYNNRYGENRE---KVWNDILDFYVKQGKPAEVKDLN 392

  Fly   602 -------LQFLSDGHTASPLIKLGYMHSLRGGRAYFLHFKH--KTIEEEY--PQRSGSVRGEDVP 655
                   .:.|||.....|:::.......|....:.....|  |.|.:::  .|..||....:..
 Worm   393 GFYVDRYSELLSDITFNVPILREITSRVERKTPVWTYRMDHYDKNIWKKHIPEQARGSPHANEYH 457

  Fly   656 FWLGLPMSPLF-----PHNYTTQERQIGRLMLRYLSNFAKTGNPN-QSTAKSVLPNPNEVLETAL 714
            :...:|:....     |.::...:      ::..:.:|||||.|. :......:.:|::|....:
 Worm   458 YLFDMPVMAKIDMKKEPDSWIQND------LIDMVISFAKTGVPQIEDVEWRPVSDPDDVNFLNI 516

  Fly   715 HQQKKRSTSLTHPNLSEALNLAVLYNQRR-----------SNAMH 748
               :....|:.|....|.|   ..:|:.|           ::|||
 Worm   517 ---RSDGVSIEHGLFQEPL---AFWNELRQREGFDLIDPTNSAMH 555

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg2	NP_523496.1	COesterase	182..729	CDD:395084	143/577 (25%)
ges-1	NP_503411.1	COesterase	16..535	CDD:395084	145/588 (25%)