Protein Alignment Nlg2 and cest-10

DIOPT Version :9

• Sequence 1: NP_001245916.1
• Gene: Nlg2 / 33962
• FlyBaseID: FBgn0031866
• Length: 1248
• Species: Drosophila melanogaster
• Sequence 2: NP_501133.3
• Gene: cest-10 / 177493
• WormBaseID: WBGene00016595
• Length: 579
• Species: Caenorhabditis elegans
• Alignment Length: 561
• Identity: 135/561 - (24%)
• Similarity: 215/561 - (38%)
• Gaps: 145/561 - (25%)

  Fly   185 VKTKYGLLRGIVVRSSPLVEAFLGIPYASPPVGSLRFMPPITPSTWKTVRSADRFSPVCPQNIPI 249
            |:|..|.|.|..:.:..|   |..||:|.||:|.|||..|....||..||:|..:.|.|..|...
 Worm    24 VETSLGKLNGDQIGNFHL---FKKIPFAKPPLGKLRFQKPQPAETWNGVRNAKDYGPACMSNSST 85

  Fly   250 PPNGPEALLEVPRARLAQLRRLLPLLKNQSEDCLYLNIYVPYETRRQRRNTDDTTGEPKTKLSTV 314
            ...                     :.|...||||:|||:           |.:|..:.| ..:.|
 Worm    86 TKT---------------------VQKWVDEDCLHLNIF-----------TSETCLKSK-NCAVV 117

  Fly   315 VFIHGESYDWNSGNPYDGSELA---AHGNVIVVTINFRLGIFGFLKTGGKESAQGNFGLMDLVAG 376
            :::||.:..::|...::.:.|.   |...::.|....|||||.......:..|..|..|.|::..
 Worm   118 IYLHGGNLHYDSAVMFNDTFLLHTYASQEIVFVIPAVRLGIFSHFVVEDQSIAPNNLALFDMLQA 182

  Fly   377 LHWLKENLPAFGGDPQSITLLGYGTGAVLANILVVS-PVASD--LIQRTVLVSGSALSPWAIQKN 438
            :.:.|.::..|||:.:..||||:..|..:|::|..| .|.:|  |.|:.:.:|    ||......
 Worm   183 MEFAKSDIHNFGGNNKRTTLLGHSYGGTVASMLSFSTKVNTDLSLFQQYISMS----SPTNFDTL 243

  Fly   439 PLFVKR--RVAEQTGC----------HGDMLYDDLAPCLRTKSVAELLAVKVDHPRFL--VGFAP 489
            .|.|:|  |.||...|          :...:|  :..||:.||.:|||.::    |.|  .|: |
 Worm   244 ELQVERTYRFAEHANCLPKNSKFMRKNQKEVY--MRDCLKKKSASELLRIQ----RSLEEAGY-P 301

  Fly   490 FVDGTVISPGANPLGSTTLPLGSAIVSTSGIEYANFPKRDLIFCLTSVESYLDLSAQDLEFGFNE 554
            ...|:|:..          |:...::..   ::.:.|..  |..||....|..|.
 Worm   302 VYGGSVMRG----------PIFQEVLER---DFMDSPNN--ITSLTGCTKYESLV---------- 341

  Fly   555 TRRDRILRTFVRNNFHYHLNEIFAVLKNEYTDWEKAIRNPLSSRDATLQFLS-DGHTASPLIKLG 618
                          :.::.|...|:....|.:..:..|:  .|::..::|.: ...|...||::
 Worm   342 --------------YDHYRNMGKALGFENYEEVNEKYRS--DSKEGKIEFDNVKNATQIMLIQI- 389

  Fly   619 YMHSLRGGRAYFLHFKHKTI-----EEEYPQRSGSVRGEDVPFWLGLPMSPLFPHNYTTQERQI- 677
                    |........|.|     |..||:.:...  :|:.|.:|:       |.:...|.:|
 Worm   390 --------RTRVNKILKKNIPAYHYEYAYPKHANHT--DDLFFIMGV-------HPFIQDENEIK 437

  Fly   678 -GRLMLRYLSNFAKTGNP---------NQSTAKSVLPNPNE 708
             |........||.|||||         |.||...|  |.||
 Worm   438 LGNFYRSMFLNFIKTGNPGNGCDGANLNGSTYFEV--NWNE 476

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg2	NP_001245916.1	COesterase	182..712	CDD:278561	135/561 (24%)
cest-10	NP_501133.3	Abhydrolase	23..503	CDD:389770	135/561 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810