Protein Alignment Nlg2 and cest-5.2

DIOPT Version :9

• Sequence 1: NP_001245916.1
• Gene: Nlg2 / 33962
• FlyBaseID: FBgn0031866
• Length: 1248
• Species: Drosophila melanogaster
• Sequence 2: NP_501021.3
• Gene: cest-5.2 / 177428
• WormBaseID: WBGene00015284
• Length: 583
• Species: Caenorhabditis elegans
• Alignment Length: 637
• Identity: 147/637 - (23%)
• Similarity: 234/637 - (36%)
• Gaps: 166/637 - (26%)

  Fly   185 VKTKYGLLRGIVVRSSPLVEAFLGIPYASPPVGSLRFMPPITPSTWKTVRSADRFSPVCPQNIPI 249
            :||..|.|.|   :.|...:.|..||:|.||:|:|||..|.:...|..|.:|..:.|.|..|
 Worm    24 IKTSLGRLEG---KQSGKYQLFRRIPFAKPPIGTLRFQKPESAEKWNGVWNATEYGPACMSN--- 82

  Fly   250 PPNGPEALLEVPRARLAQLRRLLPLLKNQSEDCLYLNIYVPYETRRQRRNTDDTTGEPKTKLSTV 314
                 ....:.|:             |...||||::||:           |.|...:.| ..:.|
 Worm    83 -----STWTQSPQ-------------KWVDEDCLHVNIF-----------TSDKCLKSK-DCAVV 117

  Fly   315 VFIHGESYDWNSGNPYDGS---ELAAHGNVIVVTINFRLGIFGFLKTGGKESAQGNFGLMDLVAG 376
            |:|||....::|...::.:   |.....:||:|...||||||.......:..|..|..|.|::..
 Worm   118 VYIHGGEIVFDSAVMFNDTFLLESFVKQDVILVIPAFRLGIFSHFTVHDQNIAPNNLALYDIILA 182

  Fly   377 LHWLKENLPAFGGDPQSITLLGYGTGAVLANILVVSPVAS---DLIQRTVLVSGSALSPWAIQKN 438
            ..::|..:..||||.|.|||.|:..|..:|:::..|...:   .|.||.:::|.          |
 Worm   183 QEFVKSEIHNFGGDIQKITLFGHSYGGTIASMMAFSSEINQDLSLFQRIIVMSA----------N 237

  Fly   439 PLF------VKR--RVAEQTGCHGDMLYDDLA-------------PCLRTKSVAELLAVKVDHPR 482
            ..|      ::|  ||.:..||   .:..:||             .||:..|..|||:|:
 Worm   238 QYFDTLEEQIERSDRVVKHAGC---SVPTNLARKMNRSQKEKYMMKCLQKLSGMELLSVQ----- 294

  Fly   483 FLVGFAPFVDGTVISPGANPLGSTTLPLGSAIVSTSGIEYANFPKR-DLIFCLTSVESYLDLSAQ 546
                      .::...|...:|:..| .|......:.:|....||. .::...|..||    ..:
 Worm   295 ----------RSLEEAGYPDIGNLVL-RGPLFPDVTSLEMLESPKMIPMLAGCTKFES----DDE 344

  Fly   547 D------LEFGF-NETRRDRILRTFVRNNFHYHLNEIFAVLKNEYTDWEKAIRNPLSSRDATLQF 604
            |      ..||. |....|...|..:.|.       ||.  :..::|..:||..|...|
 Worm   345 DETHFIGKHFGLENPIECDEKYRKDLENG-------IFD--RQNHSDKTQAIMVPTKLR------ 394

  Fly   605 LSDGHTASPLIKLGYMHSLR--GGRAYFLHFKHKTIEEEYPQRSGSVRGEDVPFWLGLPMSPLFP 667
                           :..||  |..||...|       .||:.  :...:|:.:.:|     :.|
 Worm   395 ---------------VDQLRKHGVPAYLYEF-------TYPKH--AFHTDDLYYIMG-----IHP 430

  Fly   668 HNYTTQERQIGRLMLRYLSNFAKTGNP---------NQSTAKSVLPNPNEVLETALHQQKKRSTS 723
            ......|..:.::....|.||.|.|.|         |:||...:.  .||........:|:...:
 Worm   431 FEKDENEEHLEKVYRNMLINFIKFGEPGMGFEMSDLNESTYFEIY--WNETTGQKPRMRKRFEEN 493

  Fly   724 LTHPNLSEAL----NLA-VLYNQRRSNAMHEKRSYIRRRLRSNDAAFTQLGI 770
            :|:..|.|.:    |:. ...|||....:.:...:..:.|..||.:...:||
 Worm   494 ITNYWLKEMMEYDRNITKAKKNQRSIKPVFKTEQFYVKSLEKNDGSHEFIGI 545

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg2	NP_001245916.1	COesterase	182..712	CDD:278561	134/572 (23%)
cest-5.2	NP_501021.3	Abhydrolase	23..498	CDD:389770	136/588 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810