Protein Alignment Nlg2 and Ces2c

DIOPT Version :9

• Sequence 1: NP_001245916.1
• Gene: Nlg2 / 33962
• FlyBaseID: FBgn0031866
• Length: 1248
• Species: Drosophila melanogaster
• Sequence 2: NP_598270.2
• Gene: Ces2c / 171118
• RGDID: 621510
• Length: 561
• Species: Rattus norvegicus
• Alignment Length: 722
• Identity: 181/722 - (25%)
• Similarity: 282/722 - (39%)
• Gaps: 217/722 - (30%)

  Fly   152 QPGHPEACALL--VLLLLTSLW-PDCCECLHGGSNTVKTKY-GLLRGIV--VRSSPL-VEAFLGI 209
            || |....|:|  :||:|..:| .|..|     |::::|.: |.:||.:  ||.:.. |..||||
  Rat     5 QP-HSWLNAVLFGLLLILIHVWGQDSPE-----SSSIRTTHTGQVRGKLDHVRDTKAGVHTFLGI 63

  Fly   210 PYASPPVGSLRFMPPITPSTWKTVRSADRFSPVCPQNIPIPPNGPEALLEVPRARLAQLRRLLPL 274
            |:|..|||.|||.||..|..|..||.......:|.|||       :.|.||....:..:...:|:
  Rat    64 PFAKAPVGPLRFAPPEDPEPWSGVRDGTSHPAMCLQNI-------DMLDEVGLTDMKMILSSIPM 121

  Fly   275 LKNQSEDCLYLNIYVPYETRRQRRNTDDTTGEPKTKLSTVVFIHGESYDWNSGNPYDGSELAAHG 339
                ||||||||||.|.....            .:.|..:|.|||.:......:..|||.||.:.
  Rat   122 ----SEDCLYLNIYTPAHAHE------------GSNLPVMVCIHGGALVIGMASMCDGSLLAVNE 170

  Fly   340 NVIVVTINFRLGIFGFLKTGGKESAQGNFGLMDLVAGLHWLKENLPAFGGDPQSITLLGYGTGAV 404
            :::||.|.:|||:.||..| |.|.|:||:|.:|.||.|.|:::|:..|||:|..:|:.|...|..
  Rat   171 DLVVVAIQYRLGVLGFFST-GDEHARGNWGYLDQVAALRWVQQNIAHFGGNPNRVTIFGVSAGGT 234

  Fly   405 LANILVVSPVASDLIQRTVLVSGSALSPWAIQKNPLFVKRRVAEQTGCHG-DMLYDDLAPCLRTK 468
            ..:..|:||::..|....::.||.||.|..|.:....|...||:.:||.. |.  :.|..|||.|
  Rat   235 SVSSHVISPMSQGLFHGAIMESGVALLPDLISETSETVSTTVAKLSGCEATDS--ETLVRCLRAK 297

  Fly   469 SVAELLAVK---------VD------HPRFLVGFAPFVDGTVISPGANPLGSTTLPLGSAIVSTS 518
            |.||:|.:.         ||      ||:.|:....|          :|:.|        |:..:
  Rat   298 SGAEILVINKVFKMIPAVVDGEFLPRHPKELLASEDF----------HPVPS--------IIGVN 344

  Fly   519 GIEYANFPKRDLIFCLT------SVESYLDLSAQDLEFGFNETRRDRILRTFVRNNFHYHLNEIF 577
            ..||          |.|      :.:...:||.::|:....:|....:|..           |..
  Rat   345 TDEY----------CCTIPMVMGTAQIIKELSRENLQAVLKDTAAQMMLPP-----------ECG 388

  Fly   578 AVLKNEY---TDWEKAIRNPLSSRDATLQFLSDGHTASPLIKLGYMHSLRGGRAYFLHFKH---- 635
            .:|..||   ||      :|.:.:....:.:.|.....|.:::.:..... ...||..|:|
  Rat   389 DLLMEEYMGNTD------DPQTLQIQYAEMMGDFLFVIPALQVAHFQRSH-APVYFYEFQHAPSY 446

  Fly   636 -KTIEEEYPQRSGSVRGEDVP------FWLGLPMSPLFPHNYTTQERQIGRLMLRYLSNFAKTGN 693
             |.:.   |....:...::||      || |:.:      ::|.:|:.:.|.|::|.:|||:.||
  Rat   447 FKNVR---PPHVKADHADEVPFVFGSFFW-GIKV------DFTEEEKLLSRRMMKYWANFARHGN 501

  Fly   694 PNQSTAKSVLPNPNEVLETALHQQKKRSTSLTHPNLSEALNLAVLYNQRRSNAMHEKRSYIRRRL 758
            ||
  Rat   502 PN--------------------------------------------------------------- 503

  Fly   759 RSNDAAFTQLGISSERDVGSYDGDELPFWDAYDVVNQLYVELGNKANIQSHYRGHKLSMWLNLIP 823
                                  .:.||:|...|...| |::|..:..:....:..:|..|...:|
  Rat   504 ----------------------SEGLPYWPVLDHDEQ-YLQLDTQPAVDRALKARRLQFWTKTLP 545

  Fly   824 QLHRHFN 830
            |..:..|
  Rat   546 QKIQELN 552

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg2	NP_001245916.1	COesterase	182..712	CDD:278561	158/569 (28%)
Ces2c	NP_598270.2	COesterase	32..540	CDD:395084	166/675 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810