Protein Alignment Nlg2 and LOC1274229

DIOPT Version :10

• Sequence 1: NP_523496.1
• Gene: Nlg2 / 33962
• FlyBaseID: FBgn0031866
• Length: 1248
• Species: Drosophila melanogaster
• Sequence 2: XP_061501508.1
• Gene: LOC1274229 / 1274229
• VectorBaseID: AGAMI1_001999
• Length: 1390
• Species: Anopheles gambiae
• Alignment Length: 1216
• Identity: 346/1216 - (28%)
• Similarity: 493/1216 - (40%)
• Gaps: 334/1216 - (27%)

  Fly   185 VKTKYGLLRGIVVRSSPL-----VEAFLGIPYASPPVGSLRFMPPITPSTWKTVRSADRFSPVCP 244
            :..|.|:|||.|....|.     |:.|||||||..||||.|||||..|..|..::.|.:.|||||
Mosquito   133 IAVKQGILRGSVRVMHPQSGLKNVDQFLGIPYAEAPVGSRRFMPPSAPIPWNGLKMATKLSPVCP 197

  Fly   245 QNIPIPPNGPEALLEVPRARLAQLRRLLPLLKNQSEDCLYLNIYVPYETRRQRRNTDDTTGEPKT 309
            ||:|...|   |.....:.|..|::||||.||.:||||||||:|||         :.|..| |:|
Mosquito   198 QNLPSLNN---ANNNYSKGRYDQIKRLLPYLKVESEDCLYLNLYVP---------SYDGIG-PQT 249

  Fly   310 KLSTVVFIHGESYDWNSGNPYDGSELAAHGNVIVVTINFRLGIFGFLKTGGKESAQGNFGLMDLV 374
            |...:|:||||||:||||||||||.||::|.|||||:||||||.||:|.|..:....||||:|.:
Mosquito   250 KYPVIVYIHGESYEWNSGNPYDGSILASYGQVIVVTLNFRLGILGFMKPGISDHTTSNFGLLDQI 314

  Fly   375 AGLHWLKENLPAFGGDPQSITLLGYGTGAVLANILVVSPVASDLIQRTVLVSGSALSPWAIQKNP 439
            |.|.|:|||:.|||||.:.:|::|.||||...|.|:|||||..|..|.:|:||||||.||:.::|
Mosquito   315 AALQWIKENIGAFGGDAKLVTVMGQGTGAACVNFLMVSPVAKGLFHRAILMSGSALSDWALTQHP 379

  Fly   440 LFVKRRVAEQTGCHGDMLYDDLAPCLRTKSVAELLAVKVDHPRFLVGFAPFVDGTVISPGANPLG 504
            |....:|.:...|..:...|::..|||.|..:|:|.||...|:|...|.|.|||.||
Mosquito   380 LQSTMQVLQGLNCPLNGENDEVTACLRRKRYSEILGVKTASPQFSTRFGPIVDGLVI-------- 436

  Fly   505 STTLP---LGSAIVSTSGIEYAN-FPKRDLIFCLTSVESYLDLSAQDLEFGFNETRRDRILRTFV 565
             ..:|   :|         :|:: |...||::.:|.:|||..|:|..|.:|..|..||.:||.::
Mosquito   437 -PNMPHKVMG---------QYSDIFSGYDLLYGMTELESYHILNAVALTYGLLENERDNLLRFYM 491

  Fly   566 RNNFHYHLNEIFAVLKNEYTDW----EKAIRNPLSSRDATLQFLSDGHTASPLIKLGYMHSLRGG 626
            :|.|....:...|....||||.    .||:.:  ..||..|:.|||...|:|:::.|...|....
Mosquito   492 QNRFEIRPDLALAATLREYTDIYMDPNKALAD--EHRDNLLEILSDARVAAPMVQTGLYLSKVNP 554

  Fly   627 RAYFLHFKHKTIEEEYPQRSGSVRGEDVPFWLGLPMSPL--FPHNYTTQERQIGRLMLRYLSNFA 689
            :.|...|.|.:...||.:.|.||.|||:.:..|.|:..:  |.|:|..:||.....:::|.||||
Mosquito   555 KCYMYVFGHNSEAGEYGRLSQSVVGEDLAYVFGAPLGQVGPFQHHYNARERLFSEAVMKYFSNFA 619

  Fly   690 KTGNPNQSTAKSVLPNPNEVLETALHQQKKRSTSLTHPNLSEALNLAVLYNQRRSNAMHEKRSYI 754
            ||||| ::..|.:..|.|.                                        |..||
Mosquito   620 KTGNP-KAPWKDLFLNLNP----------------------------------------EDWSY- 642

  Fly   755 RRRLRSNDAAFTQLGISSERDVGSYDGDELPFWDAYDVVNQLYVELGNKANIQSHYRGHKLSMWL 819
                                    ||.|    |..|:.:||.|:.:|....:...||...:..|.
Mosquito   643 ------------------------YDVD----WPEYNSINQSYLHMGITPVVGHRYRQKYMKFWN 679

  Fly   820 NLIPQLHRHFNINDQSMRHHQFQDDMNNRDLYEGVVRPQLQTKPAEDDNIIIMQRSRTTTPPP-- 882
            ..:|:..:...   .|..:..:.|..:         .|....|.....:.::.:....|||.|
Mosquito   680 EELPEELKKIT---SSKAYAPYSDFFS---------PPGAGGKQGGGVSAVVGRMRGGTTPHPDY 732

  Fly   883 ----------------PSKNPSTNAT-QALNPL-GTG---TPTTT------ECGIDGA-MSVSEL 919
                            |:::|..... |..:|| |.|   .|.|:      |.|...| ::...|
Mosquito   733 PTGHINLYPIHVDIERPTEDPFRELLYQMKDPLAGPGMYNAPATSSAAAIPEKGASPAQLAAGVL 797

  Fly   920 TTTQSPK----DNRTGIVRVETQKDLATASTGIIGNLELLRRLGGKQFQSYTTALIATVAVGCFL 980
            ...:.||    ..:.|...|..:::|...:|.|:            :.:|..|.|||...|   .
Mosquito   798 EHPKHPKQLQQSGKDGPFGVTDEQELDGGATEIM------------KSESTLTILIAVAIV---F 847

  Fly   981 LILNVLIFAGIYHQREKRARDAKTKEELQEGDNSKNSSILKLNALMGGGGACGSGPGDIA----- 1040
            |:.|:::..|...:|.                             :|..|..|.|.|.:|
Mosquito   848 LLFNIVVIVGYLVRRH-----------------------------LGRPGVGGVGVGGVAGGRKV 883

  Fly  1041 ----DAYTLSGSVVDSKGGVGVVFGEYSC----------YDEKTKQLKEEKLLVELPPSSS---- 1087
                |...|..:......|||:...|..|          :......|.:|...:.|..|:|
Mosquito   884 KRKYDDTMLESAAAVVVAGVGLGEKEDGCNQLHGHHHHHHLPHGAYLLDEAATMMLRKSNSYEPV 948

  Fly  1088 ---------TGQTSLMID---------NWGACSTS--------------TLDLLKTKPG------ 1114
                     .|..|:.:|         :|...|..              .:|......|
Mosquito   949 AKQPFGGELHGPVSIGVDAVDAHTKVCDWMVASAGCRMAPAVPPHKISVAIDATPQARGNSVLRQ 1013

  Fly  1115 DPIEMV-----TYSALPSV---------------------MESTSAMSSKRGSFVDTT------- 1146
            :|||:.     .|.|...|                     ..|:|..||...|...|.
Mosquito  1014 EPIEITKAKSFEYGATDEVDCAVSGCPGEGRMGEGDASGTGSSSSGTSSSCSSSATTDELKQTMP 1078

  Fly  1147 -----LQFNSPQQFDYAVQ---------SSDQMSFKAIEDAVKAAAGHDSEITRDDDIPEPPPPP 1197
                 |.:|.|   ||.|:         ..:..||  ||.  ...||..:..:||....:.|..|
Mosquito  1079 GAGAGLYYNCP---DYPVRRFGATGEGGEEEVTSF--IEQ--DTPAGDINVTSRDKSTEKDPLSP 1136

  Fly  1198 RSFLAAQQQQQQQQ---QQQQTGILRQTGAGGTSTSGSASGSGKKR 1240
            ...|...|::...:   ...:||     |.||.:|.|:   |.|:|
Mosquito  1137 EEALRVIQRRNFPKVLPDHPRTG-----GTGGPTTVGT---SMKRR 1174

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg2	NP_523496.1	COesterase	182..729	CDD:395084	227/558 (41%)
LOC1274229	XP_061501508.1	None