Protein Alignment Nlg2 and Ces1g

DIOPT Version :9

• Sequence 1: NP_001245916.1
• Gene: Nlg2 / 33962
• FlyBaseID: FBgn0031866
• Length: 1248
• Species: Drosophila melanogaster
• Sequence 2: NP_067431.2
• Gene: Ces1g / 12623
• MGIID: 88378
• Length: 565
• Species: Mus musculus
• Alignment Length: 695
• Identity: 173/695 - (24%)
• Similarity: 271/695 - (38%)
• Gaps: 182/695 - (26%)

  Fly   159 CALLVLLLLTSL------WPDCCECLHGGSNTVKTKYGLLRGIVVRSSPLVEAFLGIPYASPPVG 217
            |||.::.|...|      .|.....:||   .|..||..|.|.   |.| |..|||:|:|.||:|
Mouse     4 CALSLISLTACLSLGHPSLPPVVHTVHG---KVLGKYVTLEGF---SQP-VAVFLGVPFAKPPLG 61

  Fly   218 SLRFMPPITPSTWKTVRSADRFSPVCPQNIPIPPNGPEALLEVPRARLAQL----RRLLPLLKNQ 278
            ||||.||.....|..|:....:.|:|.||       |||.|     |||:|    |:::|  ...
Mouse    62 SLRFAPPEPAEPWSFVKHTTSYPPLCYQN-------PEAAL-----RLAELFTNQRKIIP--HKF 112

  Fly   279 SEDCLYLNIYVPYETRRQRRNTDDTTGEPKTKLSTVVFIHGESYDWNSGNPYDGSELAAHGNVIV 343
            ||||||||||.|.:..:..|            |..:|:|||.....:..:.|||..||.|.||:|
Mouse   113 SEDCLYLNIYTPADLTQNSR------------LPVMVWIHGGGLVIDGASTYDGVPLAVHENVVV 165

  Fly   344 VTINFRLGIFGFLKTGGKESAQGNFGLMDLVAGLHWLKENLPAFGGDPQSITLLGYGTGAVLANI 408
            |.|.:||||:||..| ..|.::||:|.:|.||.|||:::|:..|||:|.|:|:.|...|....::
Mouse   166 VVIQYRLGIWGFFST-EDEHSRGNWGHLDQVAALHWVQDNIANFGGNPGSVTIFGESAGGESVSV 229

  Fly   409 LVVSPVASDLIQRTVLVSGSALSPWAIQKNPLFVKRRVAEQTGC----HGDMLYDDLAPCLRTKS 469
            ||:||:|.:|..|.:..|....:|....:....:.:::|...||    ...|::     |||.|:
Mouse   230 LVLSPLAKNLFHRAIAQSSVIFNPCLFGRAARPLAKKIAALAGCKTTTSAAMVH-----CLRQKT 289

  Fly   470 VAELLAVK-------VD---HPRFLVGFAP-FVDGTVISPGANPL----GSTTLPLGSAIVSTSG 519
            ..|||.|.       ||   .||....|.| .:||.::......:    ...|:|.   :|..:.
Mouse   290 EDELLEVSLKMKFGTVDFLGDPRESYPFLPTVIDGVLLPKAPEEILAEKSFNTVPY---MVGINK 351

  Fly   520 IEYANFPKRDLIFCLTSVESYLDLSAQDLEFGFNETRRDRILRTFVRNNFHYHLNEIFAVLKNEY 584
            .|:.           ..:..:||       |..:|.:.|:.....:....:..||....::....
Mouse   352 HEFG-----------WIIPMFLD-------FPLSERKLDQKTAASILWQAYPILNISEKLIPAAI 398

  Fly   585 TDWEKAIRNPLSSRDATLQFLSDGHTASPLIKLGYMHSLRGGRAYFLHFKHKT--IEEEYPQR-S 646
            ..:.....:|.:..|..|..:.|.....|.:.:...|...|...|...::::.  :.::.||. .
Mouse   399 EKYLGGTEDPATMTDLFLDLIGDIMFGVPSVIVSRSHRDAGAPTYMYEYQYRPSFVSDDRPQELL 463

  Fly   647 GSVRGEDVPFWLGLPMSPLFPHNYTTQERQIGRLMLRYLSNFAKTGNPNQSTAKSVLPNPNEVLE 711
            |....|....|    .:|......:.:|..:.::::::.:|||:.||||
Mouse   464 GDHADELFSVW----GAPFLKEGASEEEINLSKMVMKFWANFARNGNPN---------------- 508

  Fly   712 TALHQQKKRSTSLTHPNLSEALNLAVLYNQRRSNAMHEKRSYIRRRLRSNDAAFTQLGISSERDV 776
                                                                             
Mouse   509 ----------------------------------------------------------------- 508

  Fly   777 GSYDGDELPFWDAYDVVNQLYVELGNKANIQSHYRGHKLSMWLNL 821
                |:.||.|..|| ..:.|:::|..|......:..::..|..|
Mouse   509 ----GEGLPHWPEYD-QKEGYLQIGVPAQAAHRLKDKEVDFWTEL 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg2	NP_001245916.1	COesterase	182..712	CDD:278561	154/555 (28%)
Ces1g	NP_067431.2	COesterase	24..545	CDD:278561	165/670 (25%)
		Aes	<121..>239	CDD:223730	51/130 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810