Protein Alignment Nlg2 and Cel

DIOPT Version :9

• Sequence 1: NP_001245916.1
• Gene: Nlg2 / 33962
• FlyBaseID: FBgn0031866
• Length: 1248
• Species: Drosophila melanogaster
• Sequence 2: NP_034015.1
• Gene: Cel / 12613
• MGIID: 88374
• Length: 599
• Species: Mus musculus
• Alignment Length: 805
• Identity: 200/805 - (24%)
• Similarity: 298/805 - (37%)
• Gaps: 274/805 - (34%)

  Fly   161 LLVLLL-LTSLWPDCCECLHGGSNTVKTKYGLLRGIVVRSSPL----VEAFLGIPYASPPVGSLR 220
            |.||.| ||......|....|   .|.|:.|.:.|:..:.|.|    |:.|.|||:|
Mouse     4 LEVLFLGLTCCLAAACAAKLG---AVYTEGGFVEGVNKKLSLLGGDSVDIFKGIPFA-------- 57

  Fly   221 FMPPITPSTWKTVRSADRFSPVCPQNIPIPPNGPEALLEVPRARLAQLRRLLPLLKNQ-----SE 280
                    |.||:.:        ||..|    |.:..|:....:    :|.|.....|     .|
Mouse    58 --------TAKTLEN--------PQRHP----GWQGTLKATNFK----KRCLQATITQDNTYGQE 98

  Fly   281 DCLYLNIYVPYETRRQRRNTDDTTGEPKTKLSTVVFIHGESYDWNSGNP--------YDGSELAA 337
            |||||||:||...::...|           |..:|:|:|.::...||..        |||.|:|.
Mouse    99 DCLYLNIWVPQGRKQVSHN-----------LPVMVWIYGGAFLMGSGQGANFLKNYLYDGEEIAT 152

  Fly   338 HGNVIVVTINFRLGIFGFLKTGGKESAQGNFGLMDLVAGLHWLKENLPAFGGDPQSITLLGYGTG 402
            .|||||||.|:|:|..|||.| |..:..|||||.|....:.|:|.|:.||||||.:||:.|...|
Mouse   153 RGNVIVVTFNYRVGPLGFLST-GDANLPGNFGLRDQHMAIAWVKRNIAAFGGDPDNITIFGESAG 216

  Fly   403 AVLANILVVSPVASDLIQRTVLVSGSALSPWAIQKNPLFVKRRVAEQTGC----HGDMLYDDLAP 463
            |...::..:||....||:|.:..||.|||||||||||||..:.:|::.||    .|.|     |.
Mouse   217 AASVSLQTLSPYNKGLIRRAISQSGMALSPWAIQKNPLFWAKTIAKKVGCPTEDTGKM-----AA 276

  Fly   464 CL-----RTKSVAELLAVK-----VDHPRFLVGFAPFVDGTVISPGANPLGSTTLPLGSAIVSTS 518
            ||     |..::|..|.||     |.|   .:.|.|.:||..|..  :|:..
Mouse   277 CLKITDPRALTLAYKLPVKKQEYPVVH---YLAFIPVIDGDFIPD--DPINL------------- 323

  Fly   519 GIEYANFPKRDLIFCLTSVESYL----DLSAQDLEFGFNETRRDRILRTFVRNNFHYHLNEIFAV 579
               |.|....|.|..:.:::.:|    |:.|.           |:..:|....:| |.|.....|
Mouse   324 ---YNNTADIDYIAGINNMDGHLFATIDVPAV-----------DKTKQTVTEEDF-YRLVSGHTV 373

  Fly   580 LK---------NEYTD-W-----EKAIRNPLSSRDATLQFLSDGHTASPLIKLGYMHSLRGGRAY 629
            .|         :.||: |     ::.::..:.:.:..:.||.....|....|   .|: :..:.|
Mouse   374 AKGLKGAQATFDIYTESWAQDPSQENMKKTVVAFETDVLFLIPTEIALAQHK---AHA-KSAKTY 434

  Fly   630 FLHFKHKTIEEEYPQRSGSVRGEDVPFWLGLPMSPLFPHNYTTQERQIGRLMLRYLSNFAKTGNP 694
            ...|.|.:....||:..|:...:|:.:..|.|.:.  |..|..|:|.:.:.|:.|.:|||::|:|
Mouse   435 SYLFSHPSRMPIYPKWMGADHADDLQYVFGKPFAT--PLGYRPQDRAVSKAMIAYWTNFARSGDP 497

  Fly   695 NQSTAKSVLPNPNEVLETALHQQKKRSTSLTHPNLSEALNLAVLYNQRRSNAMHEKRSYIRRRLR 759
            |...:    |.|                  ||
Mouse   498 NMGNS----PVP------------------TH--------------------------------- 507

  Fly   760 SNDAAFTQLGISSERDVGSYDGDELPFWDAYDVVNQLYVELG---NKANIQSHYRGHKLSMW--- 818
                                       |..|.:.|..|:::.   ..|:::.|.|...|..|
Mouse   508 ---------------------------WYPYTLENGNYLDITKTITSASMKEHLREKFLKFWAVT 545

  Fly   819 LNLIPQLHRHFNINDQSMRHHQFQDDMNNRDLYEGVVRPQLQTKPAEDDNIIIMQRSRTTTPPPP 883
            ..::|.                             |...|....|.|||:.:        .|.||
Mouse   546 FEVLPT-----------------------------VTGDQDTLTPPEDDSEV--------APDPP 573

  Fly   884 SKN-------PSTNATQALNPLGTG 901
            |.:       |:.::.:|..|...|
Mouse   574 SDDSQVVPVPPTDDSVEAQMPATIG 598

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg2	NP_001245916.1	COesterase	182..712	CDD:278561	166/579 (29%)
Cel	NP_034015.1	COesterase	26..542	CDD:278561	176/685 (26%)
		Aes	<117..>247	CDD:223730	57/141 (40%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	553..599		13/54 (24%)
		4 X 11 AA tandem repeats, O-glycosylated region	559..588		9/36 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR43903
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910