Protein Alignment Nlg2 and Ces1d

DIOPT Version :9

• Sequence 1: NP_001245916.1
• Gene: Nlg2 / 33962
• FlyBaseID: FBgn0031866
• Length: 1248
• Species: Drosophila melanogaster
• Sequence 2: NP_579829.3
• Gene: Ces1d / 113902
• RGDID: 70896
• Length: 565
• Species: Rattus norvegicus
• Alignment Length: 549
• Identity: 159/549 - (28%)
• Similarity: 251/549 - (45%)
• Gaps: 103/549 - (18%)

  Fly   183 NTVK----TKYGLLRGIVVRSSPLVEAFLGIPYASPPVGSLRFMPPITPSTWKTVRSADRFSPVC 243
            ||||    .||..|.|.   :.| |..|||||:|.||:|||||.||.....|..|::...:.|:|
  Rat    27 NTVKGKVLGKYVNLEGF---AQP-VAVFLGIPFAKPPLGSLRFAPPQPAEPWNFVKNTTSYPPMC 87

  Fly   244 PQNIPIPPNGPEALLEVPRARLAQLRRLLPLLKNQSEDCLYLNIYVPYETRRQRRNTDDTTGEPK 308
            .|:..    |.:.|.|:    ....:..:||  ..||||||||:|.|.:..:..|
  Rat    88 SQDAV----GGQVLSEL----FTNRKENIPL--QFSEDCLYLNVYTPADLTKNSR---------- 132

  Fly   309 TKLSTVVFIHGESYDWNSGNPYDGSELAAHGNVIVVTINFRLGIFGFLKTGGKESAQGNFGLMDL 373
              |..:|:|||........:.|||..|:||.||:||||.:||||:||..| |.|.:|||:|.:|.
  Rat   133 --LPVMVWIHGGGLVVGGASTYDGQVLSAHENVVVVTIQYRLGIWGFFST-GDEHSQGNWGHLDQ 194

  Fly   374 VAGLHWLKENLPAFGGDPQSITLLGYGTGAVLANILVVSPVASDLIQRTVLVSGSALSPWAIQKN 438
            ||.|||:::|:..|||:|.|:|:.|...|....:.||:||:|.:|..|.:..||..|:...|..:
  Rat   195 VAALHWVQDNIANFGGNPGSVTIFGESAGGFSVSALVLSPLAKNLFHRAISESGVVLTSALITTD 259

  Fly   439 PLFVKRRVAEQTGC----HGDMLYDDLAPCLRTKSVAELLAV-------KVD---HPRFLVGFAP 489
            ...:...:|..:||    ...|::     |||.|:..|||..       |:|   :|:....|.|
  Rat   260 SKPIANLIATLSGCKTTTSAVMVH-----CLRQKTEDELLETSLKLNLFKLDLLGNPKESYPFLP 319

  Fly   490 -FVDGTVISPGANPL----GSTTLPLGSAIVSTSGIEYANFPKRDLIFCLTSVESYLDLSAQDLE 549
             .:||.|:......:    ...|:|.   ||   ||.     |::..:.:.::..| .||...|:
  Rat   320 TVIDGVVLPKTPEEILTEKSFNTVPY---IV---GIN-----KQEFGWIIPTLMGY-PLSEGKLD 372

  Fly   550 FGFNETRRDRILRTFVRNNFHYHLNEIFAVLKNEY---TDWEKAIRNPLSSRDATLQFLSDGHTA 611
               .:|.:..:.:::......   .::..|:..:|   ||      :|...:|.....::|....
  Rat   373 ---QKTAKSLLWKSYPTLKIS---EKMIPVVAEKYFGGTD------DPAKRKDLFQDLVADVMFG 425

  Fly   612 SPLIKLGYMHSLRGGRAYFLHFKH----------KTIEEEYPQRSGSVRGEDVPFWLGLPMSPLF 666
            .|.:.:...|...|...:...|::          ||:..::.....||.|           ||..
  Rat   426 VPSVMVSRSHRDAGAPTFMYEFEYRPSFVSAMRPKTVIGDHGDELFSVFG-----------SPFL 479

  Fly   667 PHNYTTQERQIGRLMLRYLSNFAKTGNPN 695
            ....:.:|..:.:::::|.:|||:.|:||
  Rat   480 KDGASEEETNLSKMVMKYWANFARNGSPN 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg2	NP_001245916.1	COesterase	182..712	CDD:278561	159/549 (29%)
Ces1d	NP_579829.3	COesterase	24..545	CDD:278561	159/549 (29%)
		Aes	<121..>239	CDD:223730	53/130 (41%)
		Prevents secretion from ER. /evidence=ECO:0000255	562..565

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910