Protein Alignment Nlg2 and ces2.6

DIOPT Version :10

• Sequence 1: NP_523496.1
• Gene: Nlg2 / 33962
• FlyBaseID: FBgn0031866
• Length: 1248
• Species: Drosophila melanogaster
• Sequence 2: XP_031756661.1
• Gene: ces2.6 / 100493652
• XenbaseID: XB-GENE-6467133
• Length: 557
• Species: Xenopus tropicalis
• Alignment Length: 581
• Identity: 170/581 - (29%)
• Similarity: 265/581 - (45%)
• Gaps: 131/581 - (22%)

  Fly   161 LLVLLLLTSLWPDCCECL--HGGSN-----TVKTKYGLLRG--IVVRSSPL-VEAFLGIPYASPP 215
            |:..|||      ||..|  :|...     .:.||||.|.|  :.||.:.. |.||:|:|:|..|
 Frog     4 LIKELLL------CCVTLEIYGAGQEDARPRLTTKYGQLLGKTVNVRGADRHVHAFMGVPFAKAP 62

  Fly   216 VGSLRFMPPITPSTWKTVRSADRFSPVCPQNIPIPPNGPEALLEVPRARLAQLRRLLPLLKNQSE 280
            ||.|||..|..|..|.::|.|....|:|.|      :|.|.|:     :|.::..:||.   .||
 Frog    63 VGHLRFADPQPPEPWSSIREASVIPPMCLQ------HGMEQLI-----KLFKIEFVLPA---SSE 113

  Fly   281 DCLYLNIYVPYETRRQRRNTDDTTGEPKTKLSTVVFIHGESYDWNSGNPYDGSELAAHGNVIVVT 345
            ||||||::.|.:.:.            .:||..:|||||........:.:|||.|:.:.||:||:
 Frog   114 DCLYLNVFTPADRKE------------NSKLPVMVFIHGGGLLMGLASMFDGSALSGYENVVVVS 166

  Fly   346 INFRLGIFGFLKTGGKESAQGNFGLMDLVAGLHWLKENLPAFGGDPQSITLLGYGTGAVLANILV 410
            |.:||||.||..||.|| ||||||.:|.||.|.|::||:..|||||:|:|:.|...|.:..:..|
 Frog   167 IQYRLGILGFFSTGDKE-AQGNFGFLDQVAALKWVQENIKEFGGDPESVTIFGQSAGGLSVSTHV 230

  Fly   411 VSPVASDLIQRTVLVSGSALSPWAI---QKNPLFVKRRVAEQTGCHGDMLYDDLAPCLRTKSVAE 472
            :||::..|..|.:..||.||.|..:   .:..|||:..||..:||:...|.|    ||:.|:..|
 Frog   231 LSPLSKGLFHRAIAESGVALLPGLVVSKTEEVLFVRDLVASLSGCNIKGLVD----CLKKKTEEE 291

  Fly   473 LLAVKVDHPRFLVGFAPFVDGTVISPGANPLGSTTLPLGSAIVSTSGIEYANFPKRDLIFCLTSV 537
            ::|:..                       .:..|.||   |.|             |.:|....|
 Frog   292 IMAISA-----------------------TMQFTALP---ACV-------------DGVFLPKPV 317

  Fly   538 ESYL-DLSAQDLEF--GFNETR--------------RDRILRTFVRNNFH-----YHLNEIFAVL 580
            |..| :..:..:.|  |||...              |:.:.|..|::...     :.::.:..:|
 Frog   318 EEILANKESNRVPFLIGFNNNEFGWMLPMALNISGFREGMGRKEVQSVLSALPLLHSVSSLVPLL 382

  Fly   581 KNEY---TDWEKAIRNPLSSRDATLQFLSDGHTASPLIKLGYMHSLRGGRAYFLHFKHK-----T 637
            ..||   |:.:..|||.....:..:.|:      .|.::....|...|...|...|:|:     .
 Frog   383 MKEYFGDTNDQTEIRNKFLELNGDILFV------IPALRTAQYHRDSGLPVYLYEFQHRPSLYDN 441

  Fly   638 IEEEYPQRSGSVRGEDVPFWLGLPM---SPLFPHNYTTQERQIGRLMLRYLSNFAKTGNPN 695
            .::::.:..   .|:::.|.||.|.   ..:|..:.|.:|:.:.:.|::|.:|||:.|:||
 Frog   442 SKDDFVKAD---HGDELYFVLGGPFLNGDAIFQSDGTDEEKNLSKTMMKYWANFARNGDPN 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg2	NP_523496.1	COesterase	182..729	CDD:395084	162/558 (29%)
ces2.6	XP_031756661.1	COesterase	27..536	CDD:395084	162/552 (29%)