Protein Alignment Nlg2 and ache

DIOPT Version :9

• Sequence 1: NP_001245916.1
• Gene: Nlg2 / 33962
• FlyBaseID: FBgn0031866
• Length: 1248
• Species: Drosophila melanogaster
• Sequence 2: XP_002940088.1
• Gene: ache / 100490673
• XenbaseID: XB-GENE-923160
• Length: 600
• Species: Xenopus tropicalis
• Alignment Length: 703
• Identity: 194/703 - (27%)
• Similarity: 267/703 - (37%)
• Gaps: 181/703 - (25%)

  Fly   159 CALLVLLLLTSLWPDCCECLHGGSNTVKTKYGLLRGIVVRSSPL---VEAFLGIPYASPPVGSLR 220
            |.|.:||:......|       |...|.|:.|.:||:  |...|   |.||||||:|.|||..:|
 Frog    12 CTLSLLLVPALTQSD-------GGLLVSTRSGKVRGL--RQPVLSTHVSAFLGIPFAEPPVDKMR 67

  Fly   221 FMPPITPSTWKTVRSADRFSPVCPQNI-PIPPNGPEALLEVPRARLAQLRRLLPLLKNQSEDCLY 284
            |........|..|..|..:...|.|.. .:.|..|...:..|.             :..||||||
 Frog    68 FRRSEPKKPWTDVWDATAYPNACYQYFDTLYPGFPGMEMWNPN-------------RPMSEDCLY 119

  Fly   285 LNIYVPYETRRQRRNTDDTTGEPKTKLSTV-VFIHGESYDWNSG--NPYDGSELAAHGNVIVVTI 346
            |||:||:               |:...:|| |:|:|..:...|.  :.|||..|....|||||::
 Frog   120 LNIWVPH---------------PRPSNATVMVWIYGGGFYSGSSSLDVYDGRYLCHAENVIVVSM 169

  Fly   347 NFRLGIFGFLK-TGGKESAQGNFGLMDLVAGLHWLKENLPAFGGDPQSITLLGYGTGAVLANILV 410
            |:|:|.||||. |.|...|.||.||.|....|.|:::|:..|||||:::|:.|...|||...:.|
 Frog   170 NYRVGAFGFLTLTPGSVDAPGNVGLFDQRLALQWVQDNIAFFGGDPRTVTIFGESAGAVSVGMHV 234

  Fly   411 VSPVASDLIQRTVLVSGSALSPWAI-------QKNPL---FVKRRVAEQTGCHGDMLYDDLAPCL 465
            :||.:..|..:..|.|||..:|||.       ::..|   |:..|:...|         :|..||
 Frog   235 LSPGSHHLFSKAALQSGSPNTPWATITPQEARRRTELLGKFLDCRMGNDT---------ELLNCL 290

  Fly   466 RTKSVAELLAVKVDHPRFLVGFAPFVDGTVISPGANPLGSTTLPLGSAIVSTSGIEYANFPKRDL 530
            |.|...||    :|| .|.|..||.|......|..:   :...|....|:...|    .|....|
 Frog   291 RVKQPQEL----IDH-EFSVLPAPSVFRFAFVPVPD---ADFFPEPPEILMNMG----RFKPCPL 343

  Fly   531 IFCLTSVE-SYLDLSAQDLEFGFNETRRDRILRTFVRNNFHYHL---NEI-FAVLKNEYTDW--- 587
            |..:...| ||..|....   ||::.....|.|..........:   |:| ...:..:||||
 Frog   344 IMGVNQNEGSYFLLYGAP---GFSKNNESLITREEFLGGVKMSVPQANDIALEAVVMQYTDWADE 405

  Fly   588 EKAIRNPLSSRDATLQFLSDGHTASPLIKLGYMHSLRGGRAYFLHFKHKTIEEEYPQRSGSVRGE 652
            ...::|    |:|..|.:.|.:...||.......:..|.|.|...|.|:.....:||..|...|.
 Frog   406 HAGVKN----REAMDQLVGDHNVICPLTYFAGKVAETGNRVYTYFFDHRASNLAWPQWMGVPHGY 466

  Fly   653 DVPFWLGLPMSPLFPHNYTTQERQIGRLMLRYLSNFAKTGNPNQSTAKSVLPNPNEVLETALHQQ 717
            ::.|..|||:....  |||.||..:.|.|:||.:|||:||:||:
 Frog   467 EIEFVFGLPLDANL--NYTPQEEALSRRMMRYWANFARTGDPNE--------------------- 508

  Fly   718 KKRSTSLTHPNLSEALNLAVLYNQRRSNAMHEKRSYIRRRLRSNDAAFTQLGISSERDVGSYDGD 782
                                                      .|||
 Frog   509 ------------------------------------------GNDA------------------- 512

  Fly   783 ELPFWDAYDVVNQLYVELGNK--ANIQSHYRGHKLSMWLNLIPQLHRHFNIND 833
            ..|.|..|....|.|:.|.||  ..:|. .|......|...:|:|   .||.|
 Frog   513 HQPRWPLYTASEQRYMALNNKPYQELQG-IRVQTCMFWNRFLPKL---LNITD 561

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg2	NP_001245916.1	COesterase	182..712	CDD:278561	169/555 (30%)
ache	XP_002940088.1	COesterase	31..549	CDD:395084	182/660 (28%)
		AChE_tetra	564..597	CDD:400834

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910