Protein Alignment Nlg2 and nlgn2

DIOPT Version :9

• Sequence 1: NP_001245916.1
• Gene: Nlg2 / 33962
• FlyBaseID: FBgn0031866
• Length: 1248
• Species: Drosophila melanogaster
• Sequence 2: XP_031755501.1
• Gene: nlgn2 / 100329187
• XenbaseID: XB-GENE-6034906
• Length: 810
• Species: Xenopus tropicalis
• Alignment Length: 1088
• Identity: 289/1088 - (26%)
• Similarity: 433/1088 - (39%)
• Gaps: 355/1088 - (32%)

  Fly   156 PEACALLVLLLLTSLWPDCCECLHGGSN------TVKTKYGLLRGIVVRSS-----PLVEAFLGI 209
            |:..|.|:|.||.:       |...|..      .|.|.||.|||:....:     |:|: :|||
 Frog     3 PDFRAPLILWLLAA-------CPAEGQKGDDKYPVVNTNYGKLRGVKKDLNNEILGPVVQ-YLGI 59

  Fly   210 PYASPPVGSLRFMPPITPSTWKTVRSADRFSPVCPQNIPIPPNGPEALLEVPRARLAQLRRLLPL 274
            |||:||:|..||..|..|::|..||:|..|:||||||:    :|....:.:|......:..:...
 Frog    60 PYATPPIGERRFQAPEAPASWTEVRNATTFAPVCPQNL----HGMLPGIMLPLWFTENMDVVAGY 120

  Fly   275 LKNQSEDCLYLNIYVPY---------ETRRQRRNTDDTTGEPKTKLSTVVFIHGESYDWNSGNPY 330
            ::||||||||||||||.         |..|:.::|.|.......|...::||||.||...:||.:
 Frog   121 VQNQSEDCLYLNIYVPLEDGPISKSREDPRKAQHTPDEDIRDSGKKPVMMFIHGGSYMEGTGNMF 185

  Fly   331 DGSELAAHGNVIVVTINFRLGIFGFLKTGGKESAQGNFGLMDLVAGLHWLKENLPAFGGDPQSIT 395
            |||.|||:|||||||:|:||||.||:.| |.::|:||:||:|.:..|.||:||:..|||||:.||
 Frog   186 DGSVLAAYGNVIVVTLNYRLGILGFMST-GDQAAKGNYGLLDQIQALRWLEENIGHFGGDPERIT 249

  Fly   396 LLGYGTGAVLANILVVSPVASDLIQRTVLVSGSALSPWAIQKNPLFVKRRVAEQTGCHGDMLY-- 458
            :.|.|.||...::|::|..:..|.|:.:..||:|:|.|::...||...|.:|.:.||.    |
 Frog   250 IFGSGAGASCVSLLILSHHSEGLFQKAIAQSGTAISSWSVNYEPLKYTRLLAAKVGCD----YQE 310

  Fly   459 -DDLAPCLRTKSVAELLAVKVDHPRFLVGFAPFVDGTVISPGANPLGSTTLPLGSAIVSTSGIEY 522
             .::..|||.|...:|:...:...|:.:.|.|.|||.|:            |....|:...| |:
 Frog   311 NSEMVMCLRRKPYRDLVDQDIQPARYHIAFGPVVDGDVV------------PDDPEILMEQG-EF 362

  Fly   523 ANFPKRDLIFCLTSVE--SYLD--LSAQDLEFGFNETRRDRILRTFVRNNFHYH-----LNEIFA 578
            .|:   |::..:...|  .:::  |.::|   |.:.:..|..:..||.|.:.:.     |.|
 Frog   363 LNY---DILMGVNQGEGLKFVEDTLESED---GISNSYFDFTVSNFVDNLYGFAEGKDVLRE--- 418

  Fly   579 VLKNEYTDWEKAIRNPLSSRDATLQFL-SDGHTASPLIKLGYMHSLRGGRAYFLHFKHKTIEEEY 642
            .:|..||||  |.|:....|..||..| :|....:|.|.....|:......||..|.|:...|..
 Frog   419 TIKFMYTDW--ADRDNGDMRRKTLLALFTDHQWVAPAIATAKFHAEYESPVYFYAFYHRCQAEGR 481

  Fly   643 PQRSGSVRGEDVPFWLGLPM---SPLFPHNYTTQERQIGRLMLRYLSNFAKTGNPNQSTAKSVLP 704
            |:...:..|::||:..|:||   :.|||.|::..:..:..:::.|.:||||||:|||       |
 Frog   482 PEWGEAAHGDEVPYVFGVPMVGATDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNQ-------P 539

  Fly   705 NPNEVLETALHQQKKRSTSLTHPNLSEALNLAVLYNQRRSNAMHEKRSYIRRRLRSNDAAFTQLG 769
            .|.:.  ..:|         |.||..|.:
 Frog   540 VPQDT--KFIH---------TKPNRFEEV------------------------------------ 557

  Fly   770 ISSERDVGSYDGDELPFWDAYDVVNQLYVELGNKANIQSHYRGHKLSMWLNLIPQLHRHFNINDQ 834
                            .|..::...:.|:.:|.|..::.:||.:|::.||.|:|.||
 Frog   558 ----------------VWTKFNPKEKQYLHIGLKPRVKDNYRANKVAFWLELVPHLH-------- 598

  Fly   835 SMRHHQFQDDMNNRDLYEGVVRPQLQTKPAEDDNIIIMQRSRTTTPPPPSKNPSTNATQALNPLG 899
                                   :|.|                                     |
 Frog   599 -----------------------ELNT-------------------------------------G 603

  Fly   900 TGTPTTTECGIDGAMSVSELTTTQSPKDNRTGIVRVETQKDLATASTGIIGNLELLRRLGGKQFQ 964
            ..|.|||.....|....|..:||:.|.......:.:|.:.|.....:...|:           .:
 Frog   604 LHTSTTTRQPTGGTRRTSSGSTTRRPPVTFPPDIDIEEEMDNRPRYSPFPGD-----------SR 657

  Fly   965 SYTTALIATVAVGCFLLILNVLIFAGIYHQREKRARDAKTKEELQEGDNSKNSSILKLNALMGGG 1029
            .|:|.|..|||||..||.||:|.||.:|::|::|       .||::..:|.           |.|
 Frog   658 DYSTELSVTVAVGASLLFLNILAFAALYYKRDRR-------HELRQRRHSP-----------GRG 704

  Fly  1030 GACGS-----GPGDIADAYTLSGSVVDSKGGVGVVFGEYSCYDEKTKQLKEEKLLVELPPSSSTG 1089
            |..|:     ||                                      ||:|:
 Frog   705 GVPGNDLAHHGP--------------------------------------EEELM---------- 721

  Fly  1090 QTSLMIDNWGACSTSTLDLLKTKPGDPIEMVTYSALPSVMESTSAMSSKRGSFVDTTLQFNSPQQ 1154
              ||.|...|...    ||...:|.|    :...|.|.                |.||...
 Frog   722 --SLQIKRAGGAP----DLEPLRPHD----ILRPACPP----------------DYTLALR---- 756

  Fly  1155 FDYAVQSSDQMSFKAIEDAVKAAAGHDSEITRDDDIPEPPPPPRSFLA 1202
                         :|.|||               .:|.|||||.|.:|
 Frog   757 -------------RAPEDA---------------PLPPPPPPPTSVMA 776

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg2	NP_001245916.1	COesterase	182..712	CDD:278561	193/565 (34%)
nlgn2	XP_031755501.1	COesterase	29..590	CDD:395084	205/664 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	367	1.000	Domainoid score	I918
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D80457at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9495
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010