Protein Alignment Nlg2 and nlgn1

DIOPT Version :10

• Sequence 1: NP_523496.1
• Gene: Nlg2 / 33962
• FlyBaseID: FBgn0031866
• Length: 1248
• Species: Drosophila melanogaster
• Sequence 2: XP_017949302.2
• Gene: nlgn1 / 100329186
• XenbaseID: XB-GENE-6041753
• Length: 859
• Species: Xenopus tropicalis
• Alignment Length: 886
• Identity: 256/886 - (28%)
• Similarity: 383/886 - (43%)
• Gaps: 268/886 - (30%)

  Fly   185 VKTKYGLLRGIVVRSS-----PLVEAFLGIPYASPPVGSLRFMPPITPSTWKTVRSADRFSPVCP 244
            |.|.||.:||.....:     |:|: |||:|||:||:|..||.||..|:.|..::::.:|:||||
 Frog    55 VLTTYGKVRGFKKELNNEILGPVVQ-FLGVPYAAPPIGERRFQPPEPPTMWGDIKNSTQFAPVCP 118

  Fly   245 QNIPIPPNGPEALLEVPRARLAQLRRLLPLLKNQSEDCLYLNIYVPYETRRQ------------- 296
            ||| :....||.:|.|....  .|..:...:::|||||||||||||.|..::
 Frog   119 QNI-VGGRLPEVMLPVWFTN--NLDVVSSYVQDQSEDCLYLNIYVPTEDVKRISKECARKPGKKI 180

  Fly   297 --------RRNTDD-------------TTGEPKTKLSTVVFIHGESYDWNSGNPYDGSELAAHGN 340
                    ::.|||             .:|.||   ..:|:|||.||...:||.:|||.||::||
 Frog   181 CRKEGPLTKKQTDDLGDNEGAEDEDIRDSGGPK---PVMVYIHGGSYMEGTGNVFDGSVLASYGN 242

  Fly   341 VIVVTINFRLGIFGFLKTGGKESAQGNFGLMDLVAGLHWLKENLPAFGGDPQSITLLGYGTGAVL 405
            |||:|:|:|||:.|||.| |.::::||:||:||:..|.|..||:..|||||..||:.|.|.||..
 Frog   243 VIVITVNYRLGVLGFLST-GDQASKGNYGLLDLIQALRWTSENIGFFGGDPLRITVFGSGAGASC 306

  Fly   406 ANILVVSPVA---------SDLIQRTVLVSGSALSPWAIQKNPLFVKRRVAEQTGCHGDMLYD-- 459
            .|:|.:|..:         ..|.||.:..||:|||.||:...|....|.:|.:.||:   :.|
 Frog   307 VNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTALSSWAVSFQPAKYARILATKVGCN---MSDSG 368

  Fly   460 DLAPCLRTKSVAELLAVKVDHPRFLVGFAPFVDGTVISPGANPLGSTTLPLGSAIVSTSGIEYAN 524
            :|..||:.|...||:...:...|:.:.|.|.:||.||            |....::...| |:.|
 Frog   369 ELVECLQKKPYRELVDQDIQPVRYHIAFGPVIDGDVI------------PDDPQVLMEQG-EFLN 420

  Fly   525 FPKRDLIF------CLTSVESYLD----LSAQDLEFGFNETRRDRILRTFVRNNFHYH-----LN 574
            :   |::.      .|..|||.:|    :|:.|.:|.         :..||.|.:.|.     |.
 Frog   421 Y---DIMLGVNQGEGLKFVESTVDHEDGVSSSDFDFA---------VSNFVDNLYGYTEGKDILR 473

  Fly   575 EIFAVLKNEYTDWEKAIRNPLSSRDATLQFLSDGHTASPLIKLGYMHSLRGGRAYFLHFKHKTIE 639
            |   .:|..||||... .||.:.|...|...:|....:|.:....:||..|...||..|.|....
 Frog   474 E---TIKFMYTDWADR-NNPETRRKTLLALFTDHQWVAPAVATADLHSNFGSPTYFYAFYHHCQT 534

  Fly   640 EEYPQRSGSVRGEDVPFWLGLPM---SPLFPHNYTTQERQIGRLMLRYLSNFAKTGNPNQSTAKS 701
            ::.|..:.:..|:::|:..|:||   :.|||.|::..:..:..:::.|.:||||||:|||
 Frog   535 DQVPAWADASHGDEIPYVFGIPMIGPTELFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNQ----- 594

  Fly   702 VLPNPNEVLETALHQQKKRSTSLTHPNLSEALNLAVLYNQRRSNAMHEKRSYIRRRLRSNDAAFT 766
              |.|.:.  ..:|         |.||                              |..:.|
 Frog   595 --PVPQDT--KFIH---------TKPN------------------------------RFEEVA-- 614

  Fly   767 QLGISSERDVGSYDGDELPFWDAYDVVNQLYVELGNKANIQSHYRGHKLSMWLNLIPQLHRHFNI 831
                                |..|...:|||:.:|.|..::.|||..|:::||.|:|:||
 Frog   615 --------------------WTRYSQKDQLYLHIGLKPRVKEHYRATKVNLWLELVPRLH----- 654

  Fly   832 NDQSMRHHQFQDDMNNRDLYEGVVRPQLQTKPAEDDNIIIMQRSRTTTPPPPSKNPSTNATQALN 896
                                                    :....|||     |.|||:.|.  .
 Frog   655 ----------------------------------------VMNDLTTT-----KGPSTDITS--K 672

  Fly   897 PLGTGT-PTTTECGIDGAMSVSELTTTQSPKDNRTGIVRVETQKDLATASTGIIGNLELLRRLGG 960
            |.|:.| |.|:     ...:|||....|.|..       :..::|
 Frog   673 PTGSNTVPVTS-----AFPTVSEDNFKQKPSS-------ISLERD-------------------- 705

  Fly   961 KQFQSYTTALIATVAVGCFLLILNVLIFAGIYHQREKRARD 1001
                 |:|.|..|:|||..||.||:|.||.:|::::||..|
 Frog   706 -----YSTELSVTIAVGASLLFLNILAFAALYYKKDKRRHD 741

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg2	NP_523496.1	COesterase	182..729	CDD:395084	199/611 (33%)
nlgn1	XP_017949302.2	COesterase	52..646	CDD:395084	213/700 (30%)