Protein Alignment Nlg2 and ces2

DIOPT Version :10

• Sequence 1: NP_523496.1
• Gene: Nlg2 / 33962
• FlyBaseID: FBgn0031866
• Length: 1248
• Species: Drosophila melanogaster
• Sequence 2: NP_001120019.1
• Gene: ces2 / 100144981
• XenbaseID: XB-GENE-6467140
• Length: 557
• Species: Xenopus tropicalis
• Alignment Length: 592
• Identity: 168/592 - (28%)
• Similarity: 254/592 - (42%)
• Gaps: 151/592 - (25%)

  Fly   160 ALLVLLLLTSLWPDCCECL--HGGSNT---VKTKYGLLRGIVV---RSSPLVEAFLGIPYASPPV 216
            :|:.:|||      ||..|  :|..:.   :.||||.|.|..|   .:..||..|:|:|:|.||:
 Frog     3 SLIKVLLL------CCATLEIYGTEDARPLLMTKYGQLLGKTVGAKETDRLVHVFMGVPFAKPPI 61

  Fly   217 GSLRFMPPITPSTWKTVRSADRFSPVCPQNIPIPPNGPEALLEVPRARLAQLRRLLPLLKNQSED 281
            |.|||..|..|..|.:||.|...||:|.|:..:    .|.|.:..:|:..        ....|||
 Frog    62 GPLRFEAPQPPEPWSSVREATAPSPMCLQDKEV----MELLADFFKAKFD--------FSRVSED 114

  Fly   282 CLYLNIYVPYETRRQRRNTDDTTGEPKTKLSTVVFIHGESYDWNSGNPYDGSELAAHGNVIVVTI 346
            |||||::.|.:           .|| ...|..:|||||........:.::||.|:|:.||:||:|
 Frog   115 CLYLNVFTPAD-----------KGE-NPGLPVMVFIHGGGLAIGGASMFEGSALSAYENVVVVSI 167

  Fly   347 NFRLGIFGFLKTGGKESAQGNFGLMDLVAGLHWLKENLPAFGGDPQSITLLGYGTGAVLANILVV 411
            .:||||.|||.||.|| .:||||.:|.||.|.|:::|:..|||||||:|:.|...|.:..:.||:
 Frog   168 QYRLGIMGFLSTGDKE-VRGNFGFLDQVAALQWVRDNIKDFGGDPQSVTIFGESAGGLSVSALVL 231

  Fly   412 SPVASDLIQRTVLVSGSALSPWAIQKN-----PLFVKRRVAEQTGCHGDMLYDDLAPCLRTKS-- 469
            ||::..|..|.:..||.|:.|......     ||.  ..|...:.|.    ..||..||:.|:
 Frog   232 SPLSEGLFHRAIAESGVAILPGLTASKTEEILPLL--DMVINVSSCS----VSDLVGCLKNKTED 290

  Fly   470 --------------------------VAELLAVKVDHP-RFLVGFAPFVDGTVISPGANPLGSTT 507
                                      ..|:||.|..|| .||:|......|:::....|..|
 Frog   291 EIIEITAAMRYVIFPAVVDGVFLPKPAEEILAAKESHPVPFLIGINNHEFGSMLPVTLNITG--- 352

  Fly   508 LPLGSAIVSTSGIEYANFPKRDL------IFCLTSVESYLDLSAQDLEFGFNETRRDRILRTFVR 566
                    ...|:|     |:|:      :..|.:|.|.:....::.   |.:|...:.|    |
 Frog   353 --------YREGME-----KKDIQAILGALPLLNTVSSVIPFIMEEY---FGDTNDPKEL----R 397

  Fly   567 NNFHYHLNEIFAVLKNEYTDWEKAIRNPLSSRDATLQFLSDGHTASPLIKLGYMHSLRGGRAYFL 631
            |||.....:|..|:                                |.::....|...|...||.
 Frog   398 NNFLDLAGDIIFVI--------------------------------PALRTAKYHRDSGFPVYFY 430

  Fly   632 HFKHK-----TIEEEYPQRSGSVRGEDVPFWLGLPM---SPLFPHNYTTQERQIGRLMLRYLSNF 688
            .|:|:     ..:|::.:..   .|:::.|..|.|.   ..||..|.|.:|:.:.:.:::|.:||
 Frog   431 EFQHRPSLYADSKEDFVKAD---HGDELYFVGGGPFLKNGILFKSNGTEEEKILSKTIMKYWANF 492

  Fly   689 AKTGNPN 695
            |:.|:||
 Frog   493 ARNGDPN 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg2	NP_523496.1	COesterase	182..729	CDD:395084	160/568 (28%)
ces2	NP_001120019.1	COesterase	25..536	CDD:395084	160/564 (28%)