Protein Alignment Nha1 and Slc9b2

DIOPT Version :10

• Sequence 1: NP_723224.2
• Gene: Nha1 / 33961
• FlyBaseID: FBgn0031865
• Length: 715
• Species: Drosophila melanogaster
• Sequence 2: NP_849208.4
• Gene: Slc9b2 / 97086
• MGIID: 2140077
• Length: 547
• Species: Mus musculus
• Alignment Length: 479
• Identity: 159/479 - (33%)
• Similarity: 260/479 - (54%)
• Gaps: 20/479 - (4%)

  Fly   203 EPPFWQKIFPYPLCPTFRTVSRLISIILIGVLIWVTAFVIIGDSAAPGGQLFGLVVLTVAANFGG 267
            ||...|.:..:..||....::|:|:...:.||:|...:.:.|....|||.|||:::|...:..||
Mouse    65 EPNGLQSLRRFLACPPRGCLARVITNGTMVVLLWAMVWSVTGPECLPGGNLFGIIILFYCSITGG 129

  Fly   268 YLI------SLTTLPRLIGMLLVGILFQNVGWADIDGDFSKV----TAHLRKFALTIILTRAGLE 322
            .|.      :|..||.|:||||.|.|.:|:   .:..|..::    ::.||..||::||.||||.
Mouse   130 KLFGLIKFPTLPPLPPLLGMLLAGFLLRNI---PVINDSVRIQHKWSSSLRSIALSVILVRAGLG 191

  Fly   323 MEPEAFKKVYKTILKLGIIPWCVEAVVMAVMSHFLLDLPWIWAFLLGSIIAAVSPAVVVPCLFRL 387
            ::.:|.:|:....::|.:.|..|||...|::||||:.|||.|.|:||.::.|||||||||.:..|
Mouse   192 LDSKALRKLKGVCVRLAMGPCIVEACASAILSHFLMGLPWQWGFILGFVVGAVSPAVVVPSMLLL 256

  Fly   388 RTKGYGVAKGIPTLVVAVAGVDDALSVAIFGIISTVMFSDKGLAYQIAQAPVCILGGLGFGVVWG 452
            :..||||.||||||::|....||.|::..|.....|.||.....:.|.:..:.::.|:..|...|
Mouse   257 QEGGYGVGKGIPTLLMAAGSFDDILAITGFNTCLGVAFSTGSTVFNIFRGILEVVIGVAAGSFLG 321

  Fly   453 SLARIFPEKGDAYVVPLRTLLLFTGGLMAIYGSEELGFEGAGPLAVVFSAFVSNLFWCKDGWDVE 517
            ...:.||.:....:|..|..|:....::|::.|....|.|:|.|..:..||::.:.|.....:||
Mouse   322 FFIQYFPSRDQDNLVWKRAFLVLGFAVLAVFSSVYFSFPGSGGLCTLVMAFLAGMRWTDKKSEVE 386

  Fly   518 DNPVSTAFEIFWMIFEPILFGLTGATIKIRELDSHTVSIGAACIFTGAILRILTTAGIAFGDRLN 582
                 ....:.|.:|:|:||||.||.:.|..|.:.||.:..|.:....::|||||..:......|
Mouse   387 -----KVIAVTWDVFQPLLFGLIGAEVSIVSLRAETVGLCVATLSIAVLIRILTTFLMVCFAGFN 446

  Fly   583 TKEKFFVGLSWMAKATVQAALGPVALKHLGDDATEEERNWANIVQTICVFSIVLTAPLGAIMISV 647
            .|||.|:..:|:.|||||||:|.|||........::..::...|.|:...:|::|||:|:::|.:
Mouse   447 IKEKIFISFAWLPKATVQAAIGSVALDTARSHGEKQLEDYGMDVLTVAFLAILITAPIGSLLIGL 511

  Fly   648 TGTKLLTKT--KQPQDLSGWRRSH 669
            .|.::|.|:  :..:::.|...:|
Mouse   512 LGPRVLQKSEHRTEEEVQGETSAH 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nha1	NP_723224.2	NhaP	253..>661	CDD:439796	143/419 (34%)
Slc9b2	NP_849208.4	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..68		2/2 (100%)
		NhaP	160..538	CDD:439796	127/381 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	522..547		2/14 (14%)