Protein Alignment Nha1 and NHA1

DIOPT Version :10

• Sequence 1: NP_723224.2
• Gene: Nha1 / 33961
• FlyBaseID: FBgn0031865
• Length: 715
• Species: Drosophila melanogaster
• Sequence 2: NP_013239.1
• Gene: NHA1 / 850829
• SGDID: S000004128
• Length: 985
• Species: Saccharomyces cerevisiae
• Alignment Length: 612
• Identity: 126/612 - (20%)
• Similarity: 214/612 - (34%)
• Gaps: 198/612 - (32%)

  Fly   207 WQKI------FPYPLCPTFRTVSRLISIILIGVLIWVTAFVIIGDSAAPGGQLFGLVVLTVAANF 265
            |:::      ..|.....|.::..|:|       ::|...:.||:|...|  :|||:|..|..|:
Yeast     4 WEQLEVSKAHVAYACVGVFSSIFSLVS-------LYVKEKLYIGESTVAG--IFGLIVGPVCLNW 59

  Fly   266 GGYLISLTTLPRLIGMLLVGILFQNVGWADIDG---DFSKVTAHLRKFALTIILTRAGLEMEPEA 327
                                  |..:.|.:.|.   :.:::...|:.||:.:.|.|
Yeast    60 ----------------------FNPLKWGNSDSITLEITRIVLCLQIFAVAVELPR--------- 93

  Fly   328 FKKVYKTILKLGIIPW-CVEAVVMAVM-SHFLLDLPWIW----------AFLLGSIIAAVSPAV- 379
                 |.:||    .| .|..:::.|| :.:|:...::|          :.|:.:.|.|..|.:
Yeast    94 -----KYMLK----HWVSVTMLLLPVMTAGWLIIGLFVWILIPGLNFSASLLISACITATDPILA 149

  Fly   380 --VVPCLFRLRTKGYGVAKGIPTLVVAVAGVDDALSVAIFGIISTVMFSDKGLAYQIAQAPVCI- 441
              ||...|..|..|:     :..|:.|.:|.:|.::.. |..:|..:....|...:|.:..:|:
Yeast   150 QSVVSGKFAQRVPGH-----LRNLLSAESGCNDGMAFP-FLFLSMNLILHPGNGREIVKDWICVT 208

  Fly   442 -----LGGLGFGVVWGSLARI---FPEKGDA---------YVVPLRTLLLFTGGLMAIYGSEELG 489
                 |.|...|...|.:.||   |.||.:.         |||    |.....|..:|.|.::|
Yeast   209 ILYECLFGCLLGCFIGYVGRITIRFAEKKNIIDRESFLAFYVV----LAFMCAGFGSILGVDDL- 268

  Fly   490 FEGAGPLAVVFSAFVSNLFWCKDGW---DVEDNPVSTAFEIFWMIFEPILFGLTGATIKIRELDS 551
                      ..:|.:...:..|||   ..:::.|||..:   ::.....|...||.|...:.::
Yeast   269 ----------LVSFAAGATFAWDGWFSQKTQESNVSTVID---LLLNYAYFIYFGAIIPWSQFNN 320

  Fly   552 --------HTVSIGAACIFTGAILRILTTAGIAFGDRLNTKEKFFVGLSWMAKATVQAALGPVAL 608
                    ..:.:....||...|..::....: ..|..:.:|..|||           ..||:.:
Yeast   321 GEIGTNVWRLIILSIVVIFLRRIPAVMILRPL-IPDIKSWREALFVG-----------HFGPIGV 373

  Fly   609 --------------KHLGDDAT--------EEERNW---ANIVQTICVF---------SIVLTAP 639
                          ....|:.|        ||.::|   |.|....|.|         |.|....
Yeast   374 GAIFAAILARGELESTFSDEPTPLNVVPSKEESKHWQLIACIWPITCFFIVTSIIVHGSSVAIIT 438

  Fly   640 LGAIMISVTGTKLLT--KTKQPQDLSGWRRSHRPSI----RDISI--ID----------EEEE-- 684
            ||..:.::|.||..|  .|......|.|.: ..||:    |..|:  :|          |.||
Yeast   439 LGRHLNTITLTKTFTTHTTNGDNGKSSWMQ-RLPSLDKAGRSFSLHRMDTQMTLSGDEGEAEEGG 502

  Fly   685 -REDPEIPEDKETHDNTLNNAHIPSIS 710
             |:.....||:|    .|||..|.|::
Yeast   503 GRKGLAGGEDEE----GLNNDQIGSVA 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nha1	NP_723224.2	NhaP	253..>661	CDD:439796	97/490 (20%)
NHA1	NP_013239.1	c_cpa1	2..923	CDD:273295	126/612 (21%)