Protein Alignment Nha1 and slc9a1b

DIOPT Version :10

• Sequence 1: NP_723224.2
• Gene: Nha1 / 33961
• FlyBaseID: FBgn0031865
• Length: 715
• Species: Drosophila melanogaster
• Sequence 2: NP_001106952.1
• Gene: slc9a1b / 795135
• ZFINID: ZDB-GENE-080225-42
• Length: 653
• Species: Danio rerio
• Alignment Length: 552
• Identity: 110/552 - (19%)
• Similarity: 196/552 - (35%)
• Gaps: 161/552 - (29%)

  Fly   228 IILIGVLIWVTAFVIIGDSAAPGGQLFGLVVLTVAANFGGYLISLTTLPRLIGMLLVGILFQNVG 292
            :|::|:|:.....|:..|......|||.|.:|.......||.:.:..            ..:|||
Zfish    75 LIVVGLLVGGLIRVLGEDPPVLDSQLFFLCLLPPIILDAGYFLPIRP------------FMENVG 127

  Fly   293 WADIDGDFSKVTAHLRKFALTIILTRAGLEMEPEAFKKVYKTILKLGIIPWC-VEAVVMAVMSHF 356
                                 .|||.|.|.....||      .:.:.:...| :|...:|.
Zfish   128 ---------------------TILTFAVLGTLWSAF------FMGVALYGACQLEGAELAG---- 161

  Fly   357 LLDLPWIWAFLLGSIIAAVSPAVVVPCLFRLRTKGYGVAKGIPTLVVAVAGVDDALSVAIFGIIS 421
             :||  :...|.|||::||.|..|:.....:.     :.:.:..||...:.::||::|.::.:..
Zfish   162 -VDL--LSCLLFGSIVSAVDPVAVLAVFQEIH-----INELLHILVFGESLLNDAVTVVLYHLFE 218

  Fly   422 TVMFSDKGLAYQIAQAPVCI----LGGLGFGVVWGSLARIFPEKGDAYVVPLRTLLLFTGGLMAI 482
            ..:...:..|..:....||.    :||:..|.|:|.|| .|..:..|:...:..|.:|....||
Zfish   219 EFVHRGEVTAGDVFLGVVCFFVVSVGGVLVGCVYGFLA-AFTSRFTAHTRVIEPLFVFLYSYMA- 281

  Fly   483 YGSEELGFEGAGPLAVVFSAFVSNLFWCKDGWDVEDNPVS----TAFEIF---W-MIFEPILFGL 539
            |.|.|: |..:|.:|::....|...:       ||.| :|    |..:.|   | .:.|.::|..
Zfish   282 YLSAEV-FHLSGIMALIACGVVMRPY-------VEAN-ISHKSYTTIKYFLKMWSSVSETLIFIF 337

  Fly   540 TGATIKIRELDSHTVSIGAACIFTGAIL--------RILTTAGIAF------GDRLNTKEKFFVG 590
            .|.:         ||:...|..:|...|        |:|...|:.|      ..:|:.|::|.|.
Zfish   338 LGVS---------TVAGPHAWNWTFVSLTLVLCLLSRVLGVVGLTFIINKYRMVKLSGKDQFIVA 393

  Fly   591 LSWMAKATVQAALGPVALK---HLGDDATEEERNWANIVQTICVFSIVLTAPLGAIMISVTGTKL 652
            ...:.        |.:|..   .|..::...:..:...|.|:..|::.:.......::.:...|
Zfish   394 YGGLR--------GAIAFSLAFLLSSESCAMKDLFLTAVITVIFFTVFVQGMTIRPLVDLLAVK- 449

  Fly   653 LTKTKQP--------------------QDLSG------WR-------------------RSHRPS 672
              |.||.                    :|:.|      ||                   ||..|.
Zfish   450 --KKKQSKFSVNEEIHTQFLEHLLTGIEDVCGHYGHHHWRDKISRFNKRYMMRFLIGGERSQEPQ 512

  Fly   673 IRDISIIDEEEEREDPEIPEDKETHDNTLNNA 704
            :  ||...:.|..:..::.|:..|  .:|::|
Zfish   513 L--ISFYKQMELEQTMKMLENNST--TSLSSA 540

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nha1	NP_723224.2	NhaP	253..>661	CDD:439796	90/457 (20%)
slc9a1b	NP_001106952.1	b_cpa1	36..591	CDD:273294	110/552 (20%)