Protein Alignment Nha1 and slc9a2

DIOPT Version :10

• Sequence 1: NP_723224.2
• Gene: Nha1 / 33961
• FlyBaseID: FBgn0031865
• Length: 715
• Species: Drosophila melanogaster
• Sequence 2: XP_068079528.1
• Gene: slc9a2 / 562904
• ZFINID: ZDB-GENE-070912-541
• Length: 785
• Species: Danio rerio
• Alignment Length: 465
• Identity: 77/465 - (16%)
• Similarity: 148/465 - (31%)
• Gaps: 190/465 - (40%)

  Fly   237 VTAFVIIGDSAAPGGQLFGLVVLTVAANFGGYLISLTTLPRLIGMLLVGILFQNVGWADIDGDFS 301
            :|.:|::...|..|..::..:.:.|..:.  .||||       |.::.|::..
Zfish    69 ITLWVLLASFAKIGFNVYHKITVWVPESC--LLISL-------GFVVGGVMHA------------ 112

  Fly   302 KVTAHLRK-------------FALTIILTRAGLEMEPEAFKKVYKTILKLGIIP--WCVEAV--- 348
                 :||             :.|..|:..:|..|....|.:...|::...::.  |....:
Zfish   113 -----VRKEPPAVISSNVFFLYMLPPIILESGYFMPTRPFFENVGTVMWFAVVGTLWNTMGIGIS 172

  Fly   349 ---VMAVMSHFLLDLPWIWAFLLGSIIAAVSPAVVV------------------PCLFRLRTKGY 392
               :..:....:.|:......|..:|::||.|..|:                  .|||
Zfish   173 LFAICQIEEFGVQDINLQENLLFAAILSAVEPVAVLSVFEDISINEQLYIVMFGECLF------- 230

  Fly   393 GVAKGIPTLVVAVAGVDDALSVAIFGIIS----------TVMFSDKGLAYQIAQAPVCILGGLGF 447
                            :||::|.::.:.:          .|:|.|.|..:.:.      |||:.|
Zfish   231 ----------------NDAVTVVLYNLFNHVAAMEVDEPAVIFMDIGGFFVVG------LGGIFF 273

  Fly   448 GVVWGSLARIFPEKGDAYVVPLRTLLLFTGGLMAIYGSEELGFEGAGPLAVVFSAFVSNLFWCKD 512
            |:::|.|......              |||.:..|           .||.:...:::|
Zfish   274 GLLFGFLTAFTTR--------------FTGKVREI-----------EPLVIFMFSYMS------- 306

  Fly   513 GWDVEDNPVSTAFEIFWMIFEPILFGLTG------ATIKIRELDSHTVSIGAACIFTGAILRILT 571
                            ::|.|  ||.|:.      .|:.::......|| ..:|.....:::::
Zfish   307 ----------------YLIAE--LFALSSIMAILICTLSMKYYVEENVS-QRSCTTIRHVIKMV- 351

  Fly   572 TAGIAFGDRLNTKEKFFVGLSWMAKATVQAALGPVALKHLGDDATEEERNWANIVQTICVFSIVL 636
                  |....|...||              ||.|::      .||.|.||..|:.|:  |..:.
Zfish   352 ------GSVSETLIFFF--------------LGVVSI------TTEHEWNWGYILFTL--FFTLF 388

  Fly   637 TAPLGAIMIS 646
            ...||.::::
Zfish   389 WRFLGILVLT 398

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nha1	NP_723224.2	NhaP	253..>661	CDD:439796	73/449 (16%)
slc9a2	XP_068079528.1	Na_H_Exchanger	60..617	CDD:470090	77/465 (17%)