Protein Alignment Nha1 and Slc9a7

DIOPT Version :10

• Sequence 1: NP_723224.2
• Gene: Nha1 / 33961
• FlyBaseID: FBgn0031865
• Length: 715
• Species: Drosophila melanogaster
• Sequence 2: NP_001387931.1
• Gene: Slc9a7 / 317170
• RGDID: 1561385
• Length: 727
• Species: Rattus norvegicus
• Alignment Length: 580
• Identity: 115/580 - (19%)
• Similarity: 189/580 - (32%)
• Gaps: 127/580 - (21%)

  Fly   170 GGGSSNGGANYVEESWMYNFCLKCRGEEPSASWEPPFWQKIFPYPLCPTFRTVSRLISIILIG-- 232
            |..:|:.||...:.|.|.....:...||....                  .:||.|..|:|:.
  Rat    39 GAAASSSGAAAEDSSAMEELATEKEAEESHRQ------------------DSVSLLTFILLLTLT 85

  Fly   233 -VLIWV-----------TAFVIIGDSAAPGGQLFGLVV------LTVAANFGGYLISLTTLPRLI 279
             :.||:           |...:|          :||:|      .|.|.:.....:|.|...|..
  Rat    86 ILTIWLFKHRRVRFLHETGLAMI----------YGLIVGVILRYGTPATSGRDKSLSCTQEDRAF 140

  Fly   280 GMLLV---GILFQNVGWADID-GDFSKVTAH--LRK----------FALTIILTRAGLEMEPEAF 328
            ..|||   |..|:.....:|. |..:.|..:  |||          ..|..|:..||..::...|
  Rat   141 STLLVNVSGKFFEYTLKGEISPGKINNVEQNDMLRKVTFDPEVFFNILLPPIIFHAGYSLKKRHF 205

  Fly   329 KKVYKTILKLGIIPWCVEAVVMAVMSHFLLDLPWIWAFL-----------LGSIIAAVSPAVVVP 382
            .:...:||....:...|...::..:.:.::.|..|...|           .|:||:|..|..|:.
  Rat   206 FRNLGSILAYAFLGTAVSCFIIGNLMYGVVKLMKIVGQLSDKFYYTDCLFFGAIISATDPVTVLA 270

  Fly   383 CLFRLRTKGYGVAKGIPTLVVAVAGVDDALSVAIFGIISTVMFSDKGLAYQIAQAPV-------- 439
            ....|...     ..:..|:...:.::||:::.:..  |.|.:...||......|..
  Rat   271 IFNELHAD-----VDLYALLFGESVLNDAVAIVLSS--SIVAYQPAGLNTHAFDAAAFFKSVGIF 328

  Fly   440 --CILGGLGFGVVWGSLARIFPEKGDAYVVP-LRTLLLFTGGLMAIYGSEELGFEGAGPLAVVFS 501
              ...|....|.|.|.:..:..:....:..| |.|.|.|.........:|..||.|.  :||:|.
  Rat   329 LGIFSGSFTMGAVTGVVTALVTKFTKLHCFPLLETALFFLMSWSTFLLAEACGFTGV--VAVLFC 391

  Fly   502 AFVSNLFWCKDGWDVEDNPVS-TAFEIFWMIFEPILFGLTGATIKIRELDSHTVS----IGA-AC 560
            . ::...:..:...||....| ..||:...:.|..:|...|  :.:.....|..|    ||| ..
  Rat   392 G-ITQAHYTYNNLSVESRSRSKQLFEVLHFLAENFIFSYMG--LALFTFQKHVFSPIFIIGAFVA 453

  Fly   561 IFTGAILRILTTAGIAFGDRLNTKEKFFVGLSWMAKATVQAALGPVALKHLGDDATEEERNWANI 625
            ||.|....|..   ::|...|..:.|  :|.::..........|.:|......|.....|.....
  Rat   454 IFLGRAAHIYP---LSFFLNLGRRHK--IGWNFQHMMMFSGLRGAMAFALAIRDTASYSRQMMFT 513

  Fly   626 VQTICVFSIVLTAPLGAIMISVTGTKLLTKTKQPQDLSGWRRSHRPSIRDISIIDEEEER 685
            ...:.||..|.....|.       |.:|:          | .:.|..:.::|..|:.|.|
  Rat   514 TTLLIVFFTVWVIGGGT-------TPMLS----------W-LNIRVGVEELSEEDQNEHR 555

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nha1	NP_723224.2	NhaP	253..>661	CDD:439796	92/457 (20%)
Slc9a7	NP_001387931.1	Na_H_Exchanger	94..>553	CDD:470090	98/503 (19%)