Protein Alignment Nha1 and Slc9a6

DIOPT Version :10

• Sequence 1: NP_723224.2
• Gene: Nha1 / 33961
• FlyBaseID: FBgn0031865
• Length: 715
• Species: Drosophila melanogaster
• Sequence 2: XP_036017816.1
• Gene: Slc9a6 / 236794
• MGIID: 2443511
• Length: 732
• Species: Mus musculus
• Alignment Length: 488
• Identity: 103/488 - (21%)
• Similarity: 164/488 - (33%)
• Gaps: 124/488 - (25%)

  Fly   253 LFGLVVLTV------AANFGGYLISLTTLPRLIGMLLVGILFQ----------NVGWA------- 294
            |..|.:||:      .|.|    :..|.|..:.| ||||::.:          ||..:
Mouse    81 LLTLTILTIWLFKHRRARF----LHETGLAMIYG-LLVGLVLRYGIHVPSDVNNVTLSCEVQSSP 140

  Fly   295 -----DIDGDF------SKVTAH----------LRK----------FALTIILTRAGLEMEPEAF 328
                 ::.|.|      .::::|          |||          ..|..|:..||..::...|
Mouse   141 TTLLVNVSGKFYEYTLKGEISSHELNNVQDNEMLRKVTFDPEVFFNILLPPIIFYAGYSLKRRHF 205

  Fly   329 KKVYKTILK---LG----------IIPWCVEAVVMAVMSHFLLDLPWIWAFLLGSIIAAVSPAVV 380
            .:...:||.   ||          |:..||  .:|.|......|..:....|.|:|::|..|..|
Mouse   206 FRNLGSILAYAFLGTAISCFVIGSIMYGCV--TLMKVTGQLAGDFYFTDCLLFGAIVSATDPVTV 268

  Fly   381 VPCLFRLR--TKGYGVAKGIPTLVVAVAGVDDALSVA---------IFGIISTVMFSDKGLAYQI 434
            :.....|:  .:.|.:..|...|..|||.|..:..||         .|.:  |.||...|:...|
Mouse   269 LAIFHELQVDVELYALLFGESVLNDAVAIVLSSSIVAYQPAGDNSHTFDV--TAMFKSIGIFLGI 331

  Fly   435 AQAPVCILGGLGFGVVWGSLARIFPEKGDAYVVPLRTLLLFTGGLMAIYG------SEELGFEGA 493
            ......:  |...|||...:.:.         ..||...|...||..:..      :|..||.|.
Mouse   332 FSGSFAM--GAATGVVTALVTKF---------TKLREFQLLETGLFFLMSWSTFLLAEAWGFTGV 385

  Fly   494 GPLAVVFSAFVSNLFWCKDGWDVEDNPVSTAFEIFWMIFEPILFGLTGATIKIRELDSH----TV 554
              :||:|.......:...:......:.....||:...:.|..:|...|.|  :....:|    |.
Mouse   386 --VAVLFCGITQAHYTYNNLSTESQHRTKQLFELLNFLAENFIFSYMGLT--LFTFQNHVFNPTF 446

  Fly   555 SIGA-ACIFTGAILRILTTAGIAFGDRLNTKEKFFVGLSWMAKATVQAALGPVALK-HLGDDATE 617
            .:|| ..||.|....|...:.:     ||...:..:|.::..........|.:|.. .:.|.||.
Mouse   447 VVGAFIAIFLGRAANIYPLSLL-----LNLGRRSKIGSNFQHMMMFAGLRGAMAFALAIRDTATY 506

  Fly   618 EERNWAN-----IVQTICVFSIVLTAPLGAIMI 645
            ..:...:     :..|:.||....||.|..:.|
Mouse   507 ARQMMFSTTLLIVFFTVWVFGGGTTAMLSCLHI 539

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nha1	NP_723224.2	NhaP	253..>661	CDD:439796	103/488 (21%)
Slc9a6	XP_036017816.1	Na_H_Exchanger	94..>540	CDD:470090	99/475 (21%)