Protein Alignment Nha1 and nhx-1

DIOPT Version :10

• Sequence 1: NP_723224.2
• Gene: Nha1 / 33961
• FlyBaseID: FBgn0031865
• Length: 715
• Species: Drosophila melanogaster
• Sequence 2: NP_510622.3
• Gene: nhx-1 / 181680
• WormBaseID: WBGene00003729
• Length: 514
• Species: Caenorhabditis elegans
• Alignment Length: 483
• Identity: 103/483 - (21%)
• Similarity: 164/483 - (33%)
• Gaps: 136/483 - (28%)

  Fly   207 WQKIFPYPLCPTFRTVSRLISIILIGVLIWVTAFVIIGDSAAPGGQLF-----GLVVLTVAANFG 266
            |.:    |..||           |:|:.:.:.....||....|..:.|     .|:||.:.|.|.
 Worm     9 WNR----PETPT-----------LLGLWLLLIVGAKIGFHRMPRARHFFPESAVLIVLGLFAGFT 58

  Fly   267 GY---LISLTTLPRLIGMLLVGILFQNVGWADIDGDFSKVTAHLRKFALTIILTRAGLEMEPEAF 328
            .|   .:.|...|.|..:.|                            |..|:..||..|..:||
 Worm    59 IYELWTVDLFLHPDLFFLYL----------------------------LPPIVLEAGYFMPNKAF 95

  Fly   329 KKVYKTILKLGIIPWCVEAVVMAVMSHFLLDLPWIWAF--------------LLGSIIAAVSPAV 379
            .....||        .:.||...||:.||... :|:||              |..::|:||.|..
 Worm    96 ISNITTI--------SLFAVAGTVMNIFLTSC-FIFAFQNFYDFNITIVDTLLFSTVISAVDPVA 151

  Fly   380 VVPCLFRLRTKGYGVAKGIPTLVVAVAG---VDDALSVAIF-GIISTVMFSDKGLAYQ---IAQA 437
            |:.....:...        ..|.:.|.|   ::||::|.:: ...|.|......|.||   ::..
 Worm   152 VLSVFEEIHVN--------KLLYITVFGESLLNDAVTVVLYHSFHSMVRIGQAHLIYQDYTMSMM 208

  Fly   438 PVCIL--GGLGFGVVWGSLARIFPEKGDAYVVPLRTLLLFTGGLMAIYGSEELGFEGAGPLAVVF 500
            ...::  ||:..|||:..:|.: ..|..:.|..|:.::..|...||...||.:...|.  |.:|.
 Worm   209 NFFLVSGGGILVGVVFAVVAAL-GVKWSSNVSVLQPIICITVPYMAYLCSEIVHVSGI--LGIVV 270

  Fly   501 SAFVSNLFWCKDGWDVEDNPVSTAFEIFWMIFEPILFGLTGATIKIRELDSHTVSIGAACI---- 561
            .......:......:..|..|....:......|.|:|...|.:|..::   |....|.|.:
 Worm   271 CGLCMKSYVTGSMEERADITVKYTLKTLSSCCEAIIFVFLGFSIFSKD---HKWDFGFAIVTVIT 332

  Fly   562 -FTGAILRILTTAGIAFGDRLNTKEKFFVGLSWMAKATVQAALGPVALKHLGDDATEEERNWANI 625
             |....|.:.|                   |:|:|.   :..:..::|:    |.|  ...:..:
 Worm   333 CFAARFLVVFT-------------------LTWVAN---KWRMQKISLR----DQT--IMAFGGL 369

  Fly   626 VQTICVFSIVLT-----APLGAIMISVT 648
            ...|| |.:|||     .|...||||.|
 Worm   370 RGAIC-FGLVLTIDGEVVPAKPIMISTT 396

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nha1	NP_723224.2	NhaP	253..>661	CDD:439796	94/437 (22%)
nhx-1	NP_510622.3	Na_H_Exchanger	28..486	CDD:470090	97/449 (22%)